COMBINATORIAL CHEMISTRY & POLYMER SYNTHESIS
Hoon S, Zhou B, Janda KD, Brenner S, Scolnick J. Aptamer selection by high-throughput sequencing and informatic analysis. Biotechniques. 2011;51(6):413-6. PMID: 22150332.
Dickerson TJ, Beuscher AEt, Rogers CJ, Hixon MS, Yamamoto N, Xu Y, Olson AJ, Janda KD. Discovery of acetylcholinesterase peripheral anionic site ligands through computational refinement of a directed library. Biochemistry. 2005;44(45):14845-53. PMID: 16274232.
Reed NN, Dickerson TJ, Boldt GE, Janda KD. Enantioreversal in the Sharpless asymmetric epoxidation reaction controlled by the molecular weight of a covalently appended achiral polymer. J Org Chem. 2005;70(5):1728-31. PMID: 15730294.
Lee BS, Mahajan S, Clapham B, Janda KD. Suspension ring-opening metathesis polymerization: The preparation of norbornene-based resins for application in organic synthesis. J Org Chem. 2004;69(10):3319-29. PMID: 15132537.
Lee SH, Matsushita H, Koch G, Zimmermann J, Clapham B, Janda KD. Smart cleavage reactions: The synthesis of an array of ureas from polymer-bound carbamates. J Comb Chem. 2004;6(5):822-7. PMID: 15360219.
Matsushita H, Lee S-H, Joung M, Clapham B, Janda KD. Smart cleavage reactions: The synthesis of benzimidazoles and benzothiazoles from polymer-bound esters. Tetrahedron Lett. 2004;45(2):313-6.
Ahn JM, Wentworth P, Jr., Janda KD. Soluble polymer-supported convergent parallel library synthesis. Chem Commun (Camb). 2003;10.1039/b210696e(4):480-1. PMID: 12638959.
Dickerson TJ, Reed NN, Janda KD. Soluble polymers as catalyst and reagent platforms: Liquid-phase methodologies. In: Buchmeiser MR, editor. Polymeric Materials in Organic Synthesis and Catalysis. Weinheim, Germany: Wiley-VCH Verlag Gmbh; 2003. p. 241-76.
Fujimori T, Wirsching P, Janda KD. Preparation of a Kröhnke pyridine combinatorial library suitable for solution-phase biological screening. J Comb Chem. 2003;5(5):625-31.
Gambs C, Dickerson TJ, Mahajan S, Pasternack LB, Janda KD. High-resolution diffusion-ordered spectroscopy to probe the microenvironment of JandaJel and Merrifield resins. J Org Chem. 2003;68(9):3673-8. PMID: 12713377.
Lee SH, Clapham B, Koch G, Zimmermann J, Janda KD. Solid-phase rhodium carbenoid N-H insertion reactions: The synthesis of a diverse array of indoles. J Comb Chem. 2003;5(2):188-96. PMID: 12625710.
Boyle NA, Janda KD. Formats for combinatorial synthesis: Solid-phase, liquid-phase and surface. Curr Opin Chem Biol. 2002;6(3):339-46. PMID: 12023115.
Clapham B, Lee S-H, Koch G, Zimmermann J, Janda KD. The preparation of polymer bound β-ketoesters and their conversion into an array of oxazoles. Tetrahedron Lett. 2002;43(31):5407-10.
Delgado M, Janda KD. Polymeric supports for solid phase organic synthesis. Curr Org Chem. 2002;6(12):1031-43.
Dickerson TJ, Reed NN, Janda KD. Soluble polymers as scaffolds for recoverable catalysts and reagents. Chem Rev. 2002;102(10):3325-44. PMID: 12371887.
Gao C, Mao S, Kaufmann G, Wirsching P, Lerner RA, Janda KD. A method for the generation of combinatorial antibody libraries using pIX phage display. Proc Natl Acad Sci U S A. 2002;99(20):12612-6. PMID: 12239343.
Janda K. Polymer supported catalysts and reagents in synthetic organic chemistry. Bioorg Med Chem Lett. 2002;12(14):viii.
Reed NN, Delgado M, Hereford K, Clapham B, Janda KD. Preparation of soluble and insoluble polymer supported IBX reagents. Bioorg Med Chem Lett. 2002;12(15):2047-9. PMID: 12113839.
Shimomura O, Clapham B, Spanka C, Mahajan S, Janda KD. Application of microgels as polymer supports for organic synthesis: Preparation of a small phthalide library, a scavenger, and a borohydride reagent. J Comb Chem. 2002;4(5):436-41. PMID: 12217015.
Spanka C, Wentworth P, Jr., Janda KD. Developing soluble polymers for high-throughput synthetic chemistry. Comb Chem High Throughput Screen. 2002;5(3):233-40. PMID: 11966431.
Spanka C, Clapham B, Janda KD. Preparation of new microgel polymers and their application as supports in organic synthesis. J Org Chem. 2002;67(9):3045-50. PMID: 11975565.
Brümmer O, Clapham B, Janda KD. Solid-phase synthesis of oligoesters using a JandaJel™ resin. Tetrahedron Lett. 2001;42(12):2257-9.
Clapham B, Reger TS, Janda KD. Polymer-supported catalysis in synthetic organic chemistry. Tetrahedron. 2001;57(22):4637-62.
Dickerson TJ, Reed NN, Janda KD. Regio-reactive resin: A platform for orthogonal loading using the polymer backbone and cross-linker. Bioorg Med Chem Lett. 2001;11(12):1507-9. PMID: 11412970.
Toy PH, Reger TS, Garibay P, Garno JC, Malikayil JA, Liu G, Janda KD. Polytetrahydrofuran cross-linked polystyrene resins for solid-phase organic synthesis. J Comb Chem. 2001;3(1):117-24. PMID: 11148072.
Brümmer O, Clapham B, Janda KD. Recent developments and applications of polymer-supported reagents in synthetic organic chemistry. Curr Opin Drug Discov Devel. 2000;3(4):462-73. PMID: 19649877.
Lopez-Pelegrin JA, Janda KD. Solution- and soluble-polymer supported asymmetric syntheses of six-membered ring prostanoids. Chem Eur J. 2000;6(11):1917-22. PMID: 10894390.
Lopez-Pelegrin JA, Wentworth P, Jr., Sieber F, Metz WA, Janda KD. Soluble polymer-supported chemoenzymatic synthesis of the C21-C27 fragment of the bryostatins. J Org Chem. 2000;65(25):8527-31. PMID: 11112572.
Manzotti R, Janda KD. Solid and liquid phase chemistry: Development of new supports for solid phase organic synthesis and for liquid phase chemistry. Chimica Oggi - Chemistry Today 2000;18(7-8):14-8.
Manzotti R, Tang S-Y, Janda KD. Improved synthesis of prostanoids on a non-cross-linked polystyrene soluble support. Tetrahedron. 2000;56(40):7885-92.
Reed NN, Janda KD. Stealth star polymers: A new high-loading scaffold for liquid-phase organic synthesis. Org Lett. 2000;2(9):1311-3. PMID: 10810735.
Reger TS, Janda KD. Polymer-supported (salen)Mn catalysts for asymmetric epoxidation: A comparison between soluble and insoluble matrices. J Am Chem Soc. 2000;122(29):6929-34.
Toy PH, Reger TS, Janda KD. Tailoring polystyrene solid-phase synthesis resins: Incorporation of flexible cross-linkers. Aldrichimica Acta. 2000;33(3):87-93.
Toy PH, Reger TS, Janda KD. Soluble polymer bound cleavage reagents: A multipolymer strategy for the cleavage of tertiary amines from REM resin. Org Lett. 2000;2(15):2205-7. PMID: 10930244.
Toy PH, Janda KD. Soluble polymer-supported organic synthesis. Acc Chem Res. 2000;33(8):546-54. PMID: 10955985.
Tremblay MR, Wentworth P, Jr., Lee GE, Jr., Janda KD. Parallel solid-phase synthesis and structural characterization of a library of highly substituted chiral 1,3-oxazolidines. J Comb Chem. 2000;2(6):698-709. PMID: 11126298.
Vaino AR, Goodin DB, Janda KD. Investigating resins for solid phase organic synthesis: The relationship between swelling and microenvironment as probed by EPR and fluorescence spectroscopy. J Comb Chem. 2000;2(4):330-6. PMID: 10891099.
Vaino AR, Janda KD. Euclidean shape-encoded combinatorial chemical libraries. Proc Natl Acad Sci U S A. 2000;97(14):7692-6. PMID: 10884401.
Vaino AR, Janda KD. Solid-phase organic synthesis: A critical understanding of the resin. J Comb Chem. 2000;2(6):579-96. PMID: 11126287.
Wentworth AD, Wentworth P, Jr., Mansoor UF, Janda KD. A soluble polymer-supported triflating reagent: A high-throughput synthetic approach to aryl and enol triflates. Org Lett. 2000;2(4):477-80. PMID: 10814355.
Wentworth P, Jr., Janda KD, editors. A tool-box of polymer matrices for the combinatorial chemist / biotechnologist. International Convention on Agriculture, Biotechnology and Chemistry; 2000; Rome, Italy.
Garibay PW, Toy PH, Hoeg-Jensen T, Janda KD. Application of a new solid-phase resin: Benzamide ortho-lithiation and the synthesis of a phthalide library. Synlett. 1999;1999:1438-40.
Han H, Yoon J, Janda KD. Azatides as peptidomimetics: Solution and liquid phase syntheses. In: Kazmierski WM, editor. Peptidomimetics Protocols. Totowa, N.J.: Humana Press, Inc.; 1999. p. 87-102.
Han H, Vandersteen A, Janda KD. Combinatorics, peptide mimetics and combizymes. In: Tam JP, Kaumaya PTP, editors. Peptides: Frontiers of Peptide Science (Proceedings of the 15th American Peptide Symposium). Nashville, TN: Kluwer/Escom; 1999. p. 22-4.
Harwig CW, Gravert DJ, Janda KD. Soluble polymers: New options in both traditional and combinatorial synthesis. Chemtracts Organic Chemistry. 1999;12:1-26.
Lee KJ, Angulo A, Ghazal P, Janda KD. Soluble-polymer supported synthesis of a prostanoid library: Identification of antiviral activity. Org Lett. 1999;1(11):1859-62. PMID: 10836045.
Sieber F, Wentworth P, Toker JD, Wentworth AD, Metz WA, Reed NN, Janda KD. Development and application of a poly(ethylene glycol)-supported triarylphosphine reagent: Expanding the sphere of liquid-phase organic synthesis. J Org Chem. 1999;64(14):5188-92. PMID: 34237880.
Sieber F, Wentworth P, Jr., Janda KD. Exploring the scope of poly(ethylene glycol) (PEG) as a soluble polymer matrix for the Stille cross-coupling reaction. J Comb Chem. 1999;1(6):540-6. PMID: 10748731.
Toy PH, Janda KD. New supports for solid-phase organic synthesis: Development of polystyrene resins containing tetrahydrofuran derived cross-linkers. Tetrahedron Lett. 1999;40(35):6329-32.
Wentworth Jr P, D. Janda K. Liquid-phase chemistry: Recent advances in soluble polymer-supported catalysts, reagents and synthesis. Chem Commun. 1999;10.1039/A901955C(19):1917-24.
Yoon J, Han H, Janda KD. Solution and soluble polymer syntheses of azatides and azapeptides. In: Abell A, editor. Advances in Amino Acid Mimetics and Peptidomimetics. Stamford, CT: JAI Press, Inc.; 1999. p. 247-62.
Berg T, Vandersteen AM, Janda KD. High-throughput synthesis and direct screening for the discovery of novel hydrolytic metal complexes. Bioorg Med Chem Lett. 1998;8(10):1221-4. PMID: 9871739.
Gravert DJ, Datta A, Wentworth P, Janda KD. Soluble supports tailored for organic synthesis: Parallel polymer synthesis via sequential normal/living free radical processes. J Am Chem Soc. 1998;120(37):9481-95.
Gravert DJ, Janda KD. Bifunctional initiators for free radical polymerization of non-crosslinked block copolymers. Tetrahedron Lett. 1998;39(12):1513-6.
Hori M, Janda KD. A soluble polymer approach to the “fishing out" principle: Synthesis and purification of β-amino alcohols. J Org Chem. 1998;63(3):889-94. PMID: 11672090.
Hori M, Gravert DJ, Wentworth P, Jr., Janda KD. Investigating highly crosslinked macroporous resins for solid-phase synthesis. Bioorg Med Chem Lett. 1998;8(17):2363-8. PMID: 9873542.
Wentworth P, Janda KD. Generating and analyzing combinatorial chemistry libraries. Curr Opin Biotechnol. 1998;9(1):109-15.
Yoon J, Cho C-W, Han H, D. Janda K. Solution and soluble polymer syntheses of 3-aminoimidazoline-2,4-diones. Chem Commun. 1998;10.1039/A807067I(24):2703-4.
Zhao X-Y, Metz WA, Sieber F, Janda KD. Expanding on the purification methodology of polyethylene glycol (PEG) bound molecules: The synthesis of 3,5-pyrazolidinediones. Tetrahedron Lett. 1998;39(46):8433-6.
Zhao XY, Janda KD. Soluble polymer traceless linker investigations: Solvent effects on the desulfonylation of polyethylene glycol (PEG) substituted aryl alkyl sulfones with sodium amalgam. Bioorg Med Chem Lett. 1998;8(18):2439-42. PMID: 9873557.
Chen S, Janda KD. Synthesis of prostaglandin E2 methyl ester on a soluble-polymer support for the construction of prostanoid libraries. J Am Chem Soc. 1997;119(37):8724-5.
Gravert DJ, Janda KD. Soluble polyethylene glycol supports for liquid-phase combinatorial synthesis. Drugs of the Future. 1997;22(10):1147-50.
Gravert DJ, Janda KD. Synthesis on soluble polymers: New reactions and the construction of small molecules. Curr Opin Chem Biol. 1997;1(1):107-13. PMID: 9667833.
Gravert DJ, Janda KD. Organic synthesis on soluble polymer supports: Liquid-phase methodologies. Chem Rev. 1997;97(2):489-510. PMID: 11848880.
Han H, Janda KD. A soluble polymer-bound approach to the Sharpless catalytic asymmetric dihydroxylation (AD) reaction: Preparation and application of a [(DHQD)2PHAL-PEG-OMe] ligand. Tetrahedron Lett. 1997;38(9):1527-30.
Han H, Janda KD. Multipolymer-supported substrate and ligand approach to the Sharpless asymmetric dihydroxylation. Angew Chem Int Ed Engl. 1997;36(16):1731-3.
Janda KD, Gravert DJ. Organic reactions on soluble polymer supports as an alternative methodology for combinatorial solid-phase synthesis. Biotechnology International. 1997;169.
Janda KD. Book review on “Combinatorial Peptide and Nonpeptide Libraries. A Handbook”, edited by G. Jung. J Am Chem Soc. 1997;119(16):3848-.
Jung KW, Zhao X-y, Janda KD. Development of new linkers for the formation of aliphatic C-H bonds on polymeric supports. Tetrahedron. 1997;53(19):6645-52.
Wentworth Jr P, M. Vandersteen A, D. Janda K. Poly(ethylene glycol) (PEG) as a reagent support: The preparation and utility of a PEG–triarylphosphine conjugate in liquid-phase organic synthesis (LPOS). Chem Commun. 1997;10.1039/A608388I(8):759-60.
Zhao X-y, Janda KD. Syntheses of alkylated malonates on a traceless linker derived soluble polymer support. Tetrahedron Lett. 1997;38(31):5437-40.
Zhao X-y, Jung KW, Janda KD. Soluble polymer synthesis: An improved traceless linker methodology for aliphatic C-H bond formation. Tetrahedron Lett. 1997;38(6):977-80.
Gravert DJ, Janda KD. Developing small-molecule libraries for drug discovery. Trends Biotechnol. 1996;14(4):110-2. PMID: 8936429.
Gravert DJ, Janda KD. Liquid-phase combinatorial synthesis. In: Chaiken IM, Janda KD, editors. Molecular Diversity and Combinatorial Chemistry: Libraries and Drug Discovery (ACS Conference Proceedings): American Chemical Society; 1996. p. 118.
Han H, Janda KD. Soluble polymer-bound ligand-accelerated catalysis: Asymmetric dihydroxylation. J Am Chem Soc. 1996;118(32):7632-3.
Han H, Janda KD. Azatides: Solution and liquid phase syntheses of a new peptidomimetic. J Am Chem Soc. 1996;118(11):2539-44.
Janda KD, Han H. Combinatorial chemistry: A liquid-phase approach. In: Abelson JN, editor. Methods Enzymol. San Diego/London: Academic Press; 1996. p. 234-47.
Jung KW, Zhao X-Y, Janda KD. A linker that allows efficient formation of aliphatic C-H bonds on polymeric supports. Tetrahedron Lett. 1996;37(36):6491-4.
Lo LC, Lo C-HL, Janda KD, Kassel DB, Raushel FM. A versatile mechanism based reaction probe for the direct selection of biocatalysts. Bioorg Med Chem Lett. 1996;6(17):2117-20.
Vandersteen AM, Han H, Janda KD. Liquid-phase combinatorial synthesis: In search of small-molecule enzyme mimics. Mol Divers. 1996;2(1-2):89-96. PMID: 9238638.
Vandersteen AM, Janda KD. A re-examination of two linear pentapeptides claimed to be serine protease mimics. J Am Chem Soc. 1996;118(37):8787-90.
Han H, Wolfe MM, Brenner S, Janda KD. Liquid-phase combinatorial synthesis. Proc Natl Acad Sci U S A. 1995;92(14):6419-23. PMID: 7541541.
Jain RK, Janda KD, Saltzman WM. Drug discovery and delivery. Mol Med Today. 1995;1(1):4. PMID: 9415129.
Erb E, Janda KD, Brenner S. Recursive deconvolution of combinatorial chemical libraries. Proc Natl Acad Sci U S A. 1994;91(24):11422-6. PMID: 7972077.
Janda KD. Tagged versus untagged libraries: Methods for the generation and screening of combinatorial chemical libraries. Proc Natl Acad Sci U S A. 1994;91(23):10779-85. PMID: 7971962.
Nielsen J, Janda KD. Toward chemical implementation of encoded combinatorial libraries. Methods. 1994;6(4):361-71.
Nielsen J, Brenner S, Janda KD. Synthetic methods for the implementation of encoded combinatorial chemistry. J Am Chem Soc. 1993;115(21):9812-3.
PUBLICATIONS
PUBLICATIONS BY TOPIC: