The “strain-release amination” technique emerged from the Baran lab’s efforts to help Pfizer synthesize a promising cancer drug candidate.
The findings from the Parsons, Cravatt and Roberto labs point to a way that a drug might someday make it easier for smokers to quit.
The new method from the Yu lab enables researchers to add clusters of atoms called carbon fragment or functional groups to certain organic molecules more efficiently, robustly and selectively than ever before.
Professor K. Barry Sharpless and Associate Professor Peng Wu will be investigators on the new grant.