Research Advances from 2014

This year TSRI scientists continued to make strides in their quest to understand the fundamental processes of life and to advance human health.

Letter from the President

Acting President and CEO Jim Paulson shares his reflections about the institute’s accomplishments of the past year and his optimism for the future.

Scientists Open New Frontier of Vast Chemical ‘Space’

As proof-of-principle, a team from the Baran lab makes dozens of new chemical entities. The new method—which is extraordinarily robust—can be used to make pharmaceuticals, fabrics, dyes, plastics and other previously inaccessible materials.

Team Develops 'Cool' New Method for Probing How Molecules Fold

The technique, developed by the TSRI's Deniz lab and UC San Diego colleagues, lays the groundwork for better understanding misfolding-prone proteins that cause illnesses such as Alzheimer’s, Parkinson’s and Huntington’s disease.