The new study from the Ward and Saphire labs exposes how experimental drug ZMapp attacks the virus and suggests strategies to improve future therapies.
“If we can find a way to target those neurons in humans, maybe we can reduce the ‘high’ produced by the drug and reduce the withdrawal symptoms,” says Assistant Professor Olivier George.
The study from the Balch lab suggests diseases such as cystic fibrosis and Alzheimer’s can be seriously exacerbated by the body’s response, providing fundamental insights with implications for the design of new therapies.
Professor Hugh Rosen spoke to donors about his experiences with drug discovery at a recent lecture hosted by TSRI’s Office of Philanthropy.