Erin Danielle Anderson

The Scope and the Applications of the Inverse Electron Demand Diels Alder Reactions of 1, 2, 3-Triazines

Advisor: Dale L. Boger, PhD, Professor and Chair, Department of Chemistry

Steven Michael Bischof

Developing New Methods to Functionalize C-H Bonds Using a C-H Activation/M-R Functionalization Approach

Advisor: Roy A. Periana, PhD, Professor, Department of Chemistry

Steven P. Breazzano

Synthesis and Stereochemical Determination of Complestatins: Development of a Pd(0)-Mediated Indole (Macro)cyclization Reaction

Advisor: Dale L. Boger, PhD, Professor and Chair, Department of Chemistry

Jae Won Chang

Development of Selective Chemical Probes for Functional Analysis of the Serine Hydrolase Superfamily

Advisor: Benjamin F. Cravatt, PhD, Professor and Chair, Department of Chemical Physiology

Ming Zhu Chen

Heterocycle Synthesis via Titanium-Mediated Cross-Coupling of Imineswith Alkenes and Alkynes

Advisor: Glenn C. Micalizio, PhD, Associate Professor, Department of Chemistry

Stephen Suo Chen

The Study of E. coli Ribosome Biogenesis using Quantitative Mass Spectrometry

Advisor: James R. Williamson, PhD, Professor, Department of Integrative Structural and Computational Biology and Department of Chemistry

Eugene Chun

Fusion Protein Partners for the Stabilization and Crystallization of G Protein-Coupled Receptors

Advisor: Raymond C. Stevens, PhD, Professor, Department of Integrative Structural and Computational Biology

Lorenzo deLichtervelde

Small Molecules Modulating Hematopoietic Stem Cell Differentiations

Advisor: Peter G. Schultz, PhD, Professor, Department of Chemistry

Jason David Fiedler

Enzyme Packaging with Qβ Protein Nanoparticles

Advisor: M. G. Finn, PhD, Professor, Departments of Chemistry and Biochemistry, Georgia Institute of Technology

Thomas Gaj

Genetic Engineering with Customizable Recombinases and Nucleases

Advisor: Carlos F. Barbas III, PhD, Professor, Department of Chemistry

Marin Gantner

Induction of Energy Expenditure by the Estrogen Related Receptors (ERRS): Untangling Isoform-Specific Activity

Advisor: Anastasia Kralli, PhD, Associate Professor, Department of Chemical Physiology

Weiwei He

Aminoacyl-tRNA Synthetase and Charcot-Marie-Tooth Disease

Advisor: Xiang-Lei Yang, PhD, Associate Professor, Department of Chemical Physiology

David P. Horning

Evolving Ribozymes to Make RNA Aptamers

Advisor: Gerald F. Joyce, MD, PhD, Professor, Department of Cell and Molecular Biology

Yoshihiro Ishihara

Two-Phase Approach to Terpene Total Synthesis: Demonstration of a "Cyclase-Phase" Synthesis of the Eudesmane and Taxane Families

Advisor: Phil S. Baran, PhD, Professor, Department of Chemistry

Robert C. James

Synthesis and Evaluation of Vancomycin Aglycon Analogues: Reengineering Vancomycin for Dual ᴅ-Ala-ᴅ-Ala and ᴅ-Ala-ᴅ-Lac Binding

Advisor: Dale L. Boger, PhD, Professor and Chair, Department of Chemistry

Audra J. Johnson

Vascular-Targeting Bone Marrow-Derived Progenitor Cells Isolated Using an Immobilized Small Molecular Deletion Approach

Advisor: Martin Friedlander, MD, PhD, Professor, Department of Cell and Molecular Biology

Paul M. Johnson

The Role of Brain Reward Systems in Pathological Behavior: Cellular and Molecular Deconstruction of Striatal Adaptations

Advisor: Paul J. Kenny, Associate Professor, Department of Molecular Therapeutics

Angeldeep Kaur

Decoding Stereotyped Behavior: Sensory Mechanisms Underlying Inter-Male Communication

Advisor: Lisa Stowers, PhD, Associate Professor, Department of Molecular and Cellular Neuroscience

Stephanie A. Kazane

Synthesis of Antibody Conjugates using an Expanded Genetic Code

Advisor: Peter G. Schultz, PhD, Professor, Department of Chemistry

Alexander Alexandrovich Kislukhin

Oxanorbornadiene Reagents for Labeling and Release

Advisor:  M. G. Finn, PhD, Professor, Departments of Chemistry and Biochemistry, Georgia Institute of Technology

Marina Kolesnichenko

The Role of the Polyadenylation Site of the Melanocortin 1 Receptor in Generating MC1R-TUBB3 Chimeras and Attenuation of TORC1 Delays the Onset of Replicative and Ras-Induced Cellular Senescence

Advisor: Peter K. Vogt, PhD, Professor, Department of Molecular and Experimental Medicine

James P. Lajiness

I. Synthesis and Evaluation of Duocarmycin Analogues
II. Divergent Total Synthesis of (-)-Aspidospermine and (+)-Spegazzinine

Advisor: Dale L. Boger, PhD, Professor and Chair, Department of Chemistry

Crystal L. Moyer

Functional and Biochemical Studies of Membrane Penetration by Adenovirus Protein VI

Advisor: Glen R. Nemerow, PhD, Professor, Department of Immunology and Microbial Science

Amber N. Murray

Promoting Protein Folding with N-glycosylation and Amyloid Disaggregation

Advisor: Jeffery W. Kelly, PhD, Professor and Chair, Department of Molecular and Experimental Medicine

Francis Benedict Peters

Rational Protein Design with Unnatural Amino Acids

Advisor: Peter G. Schultz, PhD, Professor, Department of Chemistry

Ashley J. Pratt

Mechanistic Insights into the Roles and Consequences of Deliberate and Aberrant Oligomerization

Advisor: Elizabeth D. Getzoff, PhD, Professor, Department of Integrative Structural and Computational Biology

Hans Renata

Strategic Redox Relay Enables a Scalable Synthesis of Ouabagenin, A Bioactive Cardenolide

Advisor: Phil S. Baran, PhD, Professor, Department of Chemistry

Cory D. Rillahan

New Chemical Tools for Glycobiology and Immune Cell-Mediated Diseases

Advisor: James C. Paulson, PhD, Professor and Chair, Department of Cell and Molecular Biology

Amanda S. Rohrbach

Modulating the Immune Response:
Part I: Biochemical Activation of PAD4 and Function in Autoimmune Disease
Part II: Phage Display Tools for the Study of Protein-Protein Interactions in the Immune System

Advisor: Kerri Mowen, PhD, Assistant Professor, Department of Chemical Physiology

Lisa M. Ryno

Adapting Proteostasis through Stress-Responsive Signaling

Advisor: Jeffery W. Kelly, PhD, Professor and Chair, Department of Molecular and Experimental Medicine

Aaron C. Sather

Molecular Encapsulation and the Selective Recognition of the Uranyl Ion

Advisor: Julius Rebek Jr., PhD, Professor, Department of Chemistry

Heather Lee Schultheisz

MicroRNA Regulation of the Cell Cycle in Native Human Embryonic Stem Cells

Advisor: Jeanne F. Loring, PhD, Professor, Department of Chemical Physiology

Owen M. Siggs

Forward Genetic Analysis of Mammalian Immunity

Advisor: Bruce A. Beutler, MD, Regental Professor and Director, Center for Genetics of Host Defense, University of Texas Southwestern Medical Center

Luise Sternberg

Inositol (1,4,5) trisphosphate 3-kinase B (ItpkB) is central to thymic development by regulating Phosphoinositide 3-kinases (PI3K) downstream of mild and strong TCR signals

Advisor: Karsten Sauer, PhD, Associate Professor, Department of Immunology and Microbial Science

Bogdan Tanasa

Regulatory Genomics: HT-seq Technologies To Understand The Regulation Of Gene Expression

Advisor: M. Geoffrey Rosenfeld, MD, Professor, Department of Medicine, University of California San Diego

Ana-Florina Voica

Guided Desaturation of Unactivated Aliphatics

Advisor: Phil S. Baran, PhD, Professor, Department of Chemistry

Nathaniel S. Wang

Molecular Programming of Class-specific B Cell Memory

Advisor: Michael McHeyzer-Williams, PhD, Professor, Department of Immunology and Microbial Science

Masayuki Wasa

Part I. Pd-Catalyzed Alkyl C-H Activation
Part II. Pd-Catalyzed Aryl C-H Activation

Advisor: Jin-Quan Yu, PhD, Professor, Department of Chemistry

Peter Y. Watson

Intracellular Studies of Ribozymes and Riboswitches

Advisor: Martha J. Fedor, PhD, Professor, Department of Chemical Physiology

John Whitaker

Studies Towards the Synthesis of Sporolides A and B and Other Synthetic Efforts

Advisor: William R. Roush, PhD, Professor, Department of Chemistry

Joann Wu

Protein-Binding and RNA-Binding Properties of RNA-Binding Proteins FBF and RBM39

Advisor: James R. Williamson, PhD, Professor, Department of Integrative Structural and Computational Biology and Department of Chemistry

Jun Yin Axup

Next-Generation Antibody Therapeutics using Unnatural Amino Acids

Advisor: Peter G. Schultz, PhD, Professor, Department of Chemistry

Andrea M. Zuhl

Part I. Total Synthesis of Fendleridine and l-Acetylaspidoalbidine
Part II. Utilizing Activity-Based Protein Technologies to Develop Inhibitors for Uncharacterized Serine Hydrolases

Advisor: Benjamin F. Cravatt, PhD, Professor and Chair, Department of Chemical Physiology

Paddy Martin Barrett

Gene Expression Analysis of Circulating Endothelial Cells in Acute Myocardial Infarction

Advisor: Eric Topol, MD, Professor, Department of Molecular and Experimental Medicine and Scripps Translational Science Institute

Ravichendra Komatireddy

Design, Development, and Testing of a Novel Telemedicine Program for Rehabilitation

Advisor: Eric Topol, MD, Professor, Department of Molecular and Experimental Medicine and Scripps Translational Science Institute

Liliana Uribe-Bruce

Implications of Genomic Studies of Type 2 Diabetes in Immigrant Admixed Populations

Advisors: Athene Philis-Tsimikas, MD, Scripps Translational Science Institute, Nicholas Schork, PhD, Professor, Department of Molecular and Experimental Medicine