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The Class of 2012
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The Class of 2012

aversa

Robert John Aversa


A Furan-Based Strategy Towards the Total Synthesis of Maitotoxin


Advisor: K. C. Nicolaou, PhD, Professor and Chair, Department of Chemistry


aversa

Gira Bhabha


Life in (Atomic) Motion: Protein Dynamics in Enzyme Catalysis


Advisors: Peter Wright, PhD, Chair, Department of Molecular Biology Jane Dyson, PhD, Professor, Department of Molecular Biology


blankman

Jacqueline L. Blankman


Characterization of Lipid Hydrolases in Endocannabinoid Signaling and Neurodegeneration


Academic Advisor: Benjamin F. Cravatt, PhD, Professor and Chair, Department of Chemical Physiology


chen

Ming Chen


Development of Functionalized Chiral Allylboranes via Allene Hydroboration and Applications in Natural Products Synthesis


Advisor: William R. Roush, PhD, Professor, Department of Chemistry


chitt

Johnathan R. Chittuluru


Structural Studies of the Yeast NuA4 and Piccolo-NuA4 Histone Acetyltransferases and the Human α-Synuclein Protein


Advisor: Francisco Asturias, PhD, Associate Professor, Department of Cell Biology


crumbley

Christine A. Crumbley


The Role of Retinoic Acid Receptor-Related Orphan Receptors (RORs) and REV-ERB Receptors in Regulating Circadian Rhythms and Metabolism


Advisor: Thomas Burris, PhD, Professor, Department of Molecular Therapeutics


dambacher

Cory Michael Dambacher


Mutation and Modulation of Translational Machinery in E. coli

 

Advisor:Peter G. Schultz, PhD, Professor, Department of Chemistry


dambacher

Stephen M. Dean


Chemical Glycobiology: Development and Application of Chemical and Enzymatic Methods for the Study of Glycoproteins

 

Advisor: Chi-Huey Wong, PhD, Professor, Department of Chemistry


dix

Melissa M. Dix


Development and Application of Advanced Proteomic Methods to Globally Map Protease Substrate Profiles


Advisor: Benjamin F. Cravatt, PhD, Professor and Chair, Department of Chemical Physiology


dix

Damian Charles Ekiert


Structural Basis of Influenza Virus Inhibition by Broadly Neutralizing Antibodies


Advisor: Ian A. Wilson, D. Phil., D.Sc. FRS, Professor, Department of Molecular Biology


ellery

Shelby Paige Ellery


I. Synthesis and Biological Evaluation of Bridged Nucleosides and BE-43472B Analogues II. Progress Towards the Total Synthesis and Structural Determination of Brasiliensophyllic Acid A


Advisor: K. C. Nicolaou, PhD, Professor and Chair, Department of Chemistry


elliott

Hunter Lee Elliott


Cell Shape Invariant Quantification of Morphology, Migration and Subcellular Dynamics


Advisor: Gaudenz Danuser, PhD, Professor, Department of Cell Biology, Harvard Medical School


grig

Yevgeniy Grigoryev


Post-transcriptional Mechanisms of Gene Regulation and Information Control in Immunity


Advisor: Daniel R. Salomon, MD, Professor, Department of Molecular and Experimental Medicine


halvorsen

Geoff T. Halvorsen


Studies on the Intramolecular Diels-Alder Reaction


Advisor: William R. Roush, PhD, Professor, Department of Chemistry


harris


David A. Harris


Novel Antibacterial Agents via the Inhibition of Bacterial Signal Peptidase


Advisor: Floyd E. Romesberg, PhD, Associate Professor, Department of Chemistry


hastie

Kathryn M. Hastie


The Lassa Virus Tool-kit for Replication, Packaging and Immune Evasion


Advisor: Erica Ollmann Saphire, PhD, Associate Professor, Department of Immunology and Microbial Science


heideker

Christine Johanna Heideker


New Roles for SUMO and SUMO-targeted Ubiquitin Ligases in Genome Stability


Advisor: Michael Boddy, PhD, Associate Professor, Department of Molecular Biology


kirch

Robert N. Kirchdoerfer


Components of Pathogenic Microorganisms and Applications in Human Health


Advisor: Ian A. Wilson, D. Phil., D.Sc. FRS, Professor, Department of Molecular Biology


kirch

Dong-In Koo


Part I. Functional Metabolomics and Genomics Approaches to Identifying Endogenous Regulators in Cellular Processes Part II. Towards Understanding of Mechanism of Action of a Neurite Outgrowth Promoting Compound


Advisor: Advisor: Peter G. Schultz, PhD, Professor, Department of Chemistry


kraw

Paul John Krawczuk


Studies Toward the Total Synthesis of Maoecrystal V


Advisor: Phil S. Baran, PhD, Professor, Department of Chemistry


kuo

Tun-Hsun Kuo


A Functional Genomic Approach to the Cellular Events in Spinal Muscular Atrophy


Advisor: Peter G. Schultz, PhD, Professor, Department of Chemistry


kwok

Sen Wai Kwok - 2011 Graduate


Synthetic Applications and Mechanistic Studies of Rhodium(II)-Catalyzed Transformations of 1,2,3-Triazoles


Advisors: K. Barry Sharpless, PhD, Professor, Department of Chemistry and Valery Fokin, PhD, Associate Professor, Department of Chemistry


leaman

Daniel P. Leaman


Stable and Homogeneous HIV-1 Envelope Glycoprotein Trimers as Vaccine Candidates and Target of Inhibitors


Advisor: Michael B. Zwick, PhD, Assistant Professor, Department of Immunology and Microbial Science


lockner

Jonathan W. Lockner


Studies in Meroterpenoid Synthesis


Advisors: Phil S. Baran, PhD, Professor, Department of Chemistry


long

Jonathan Z. Long


Annotation of Serine Hydrolase Function in Mammalian Physiology and Behavior


Advisor: Benjamin F. Cravatt, PhD, Professor and Chair, Department of Chemical Physiology


luna

Victor Mitch M. Luna


Structural Characterization of Oxygen Pathways in Cytochrome ba3 Oxidase


Advisor: C. David Stout, PhD, Associate Professor, Department of Molecular Biology


mei

Tian-Sheng Mei


Weak Coordination as a Powerful Means for Developing Useful Palladium (II)-Catalyzed C-H Activation Reactions


Advisor: Jin-Quan Yu, PhD, Professor, Department of Chemistry


miyamoto

Takashi Miyamoto


Nitric Oxide Links Skin and Sensory Neurons to Mediate Thermosensation


Advisor: Ardem Patapoutian, PhD, Professor, Department of Cell Biology


moreno

Amira Yaazim Moreno


Immunopharmacotherapy: Towards the Creation of Effective Vaccines Against Drugs of Abuse


Advisor: Kim D. Janda, PhD, Professor, Department of Chemistry


plummer

Emily Plummer


Tracking CPMV Interactions with Systems, Diseases, and Cells


Advisor: Marianne Manchester, PhD, Professor, Skaggs School of Pharmacy and Pharmaceutical SciencesUniversity of California, San Diego


presolski

Stanislav Ivaylov Presolski


Ligand-Accelerated CuI-Catalyzed Azide-Alkyne Cycloaddition: Kinetic Studies and Reaction Mechanism


Advisor: M. G. Finn, PhD, Professor, Department of Chemistry


ridgeway

William K. Ridgeway


Principles of Parallel Assembly in Bacterial 30S Ribosomes Probed with Fluorescence Triple Correlation Spectroscopy


Advisor: James R. Williamson, PhD, Professor, Departments of Molecular Biology and Chemistry


sariah

David Sarlah


Adventurous Total Synthesis: Part I. The Chemistry and Biology of Biyouyanagins Part II. Total Synthesis of Hirsutellones A, B and C


Advisor: K. C. Nicolaou, PhD, Professor and Chair, Department of Chemistry


seiple

Ian Bass Seiple


The Pursuit of Palau’amine


Advisor: Phil S. Baran, PhD, Professor, Department of Chemistry


shi

Jun Shi


Total Synthesis of Complex Natural Products: Cortistatin A, Vinigrol and Maoecrystal V


Advisor: Phil S. Baran, PhD, Professor, Department of Chemistry


shi

James P. Solomon


Probing the Molecular Pathogenesis of Gelsolin Amyloidosis


Advisor: Jeffery W. Kelly, PhD, Professor and Chair, Department of Molecular and Experimental Medicine


shi

Anne Marie W. Turner


Transcriptional Gene Silencing of HIV-1 by Non-Coding RNAs: Progress towards a TGS- Based Genetic Therapy


Advisor: Kevin Morris, PhD, Associate Professor, Department of Molecular and Experimental Medicine


tuttle

Lisa Michelle Tuttle


NMR Studies of Side Chain Conformations and Dynamics in E. Coli and Human DHFR


Advisors: Peter Wright, PhD, Chair, Department of Molecular Biology and Jane Dyson, PhD, Professor, Department of Molecular Biology


whitby

Landon R. Whitby


Comprehensive Peptidomimetic Libraries Targeting Protein-Protein Interactions


Advisor: Dale L. Boger, PhD, Professor, Department of Chemistry


Yu

Wayne Yu


Carbon-Deuterium Bonds as Probes of Protein Thermal Unfolding & Initial Efforts Toward Studying the Effects of Somatic Evolution on Antibody Backbone Dynamics by NMR Spectroscopy


Advisor: Floyd E. Romesberg, PhD, Associate Professor, Department of Chemistry






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