A paper detailing ongoing research on the synthesis of vinblastine analogues in the lab of Dale Boger, chair of the Department of Chemistry at The Scripps Research Institute (TSRI), has been selected by the publishers as the best of those appearing in Organic Letters during 2012.
Vinblastine and vincristine represent one of the earliest and most important contributions that plant-derived natural products have made to cancer chemotherapy.
In addition to Boger, the paper, titled “Iron(III)/NaBH4-Mediated Additions to Unactivated Alkenes: Synthesis of Novel 200-Vinblastine Analogues,” (Vol. 14, No. 6, 1428-1431) was authored by Erick K. Leggans (now at Grinnell College in Iowa), Research Associate Timothy J. Barker and graduate student Katharine K. Duncan.
Boger will present the paper and related efforts at a symposium during the National American Chemical Society Meeting in Indianapolis next fall.
The
Scripps Research Institute’s (TSRI) Kanny Wan is one of just 550 graduate
students worldwide selected to attend the 63rd Lindau Nobel Laureate
Meeting, an international forum of Nobel scientists and the next generation of
leading scientists and researchers.
Established in 1951, the Lindau Meeting program features lectures, discussion
sessions, master classes, panel discussions and informal encounters to
facilitate scientific exchange between generations, disciplines, and
nationalities. Thirty-five Nobel Prize winners will attend the week-long 2013 meeting,
scheduled for this summer in Lindau, Germany. The meeting will focus on green
chemistry and biochemical processes and structures.
Wan, who is a member of the
Shenvi lab at TSRI, is currently working on the total syntheses of a family of
complex marine terpenoids that exhibit selective cytotoxicity against several
lines of human cancer cells. She received a travel award from the National
Science Foundation’s Mathematical and Physical Science Directorate to attend
the Lindau Meeting.
Two upcoming career workshops for postdocs and graduate students will be presented by the Career and Postdoctoral Services Office on the Florida campus.
Career Transitions
A three-session Career Transitions Workshop, designed to help participants examine
career options within and outside academia, is scheduled Thursdays, March 14
and March 21, 1:30 to 3:30 PM, and Friday, March 22, 9:30 to 11:30 AM, in Building
B, Conference Room B393.
Workshop facilitators Ryan Wheeler, manager of the Career and Postdoctoral
Services Office, and Michael Matrone, the office’s program coordinator, will lead participants
in a confidential small-group environment, examining personal skills,
interests, values and goals.
Parrticipants must register for and commit to all three workshop sessions.
Registration is available through http://hris.scripps.edu/training/class/CTW2012FPD.
Writing and Publishing Scientific
Manuscripts
Demystifying the process of scientific manuscript writing and publishing is
the goal of a workshop scheduled for Monday, March 18, 3:30 to 5 PM, in
Classroom B159.
Conducted by Mike Matrone, program coordinator for the Career and
Postdoctoral Services Office, the session aims to help participants understand
the fundamentals of effective science writing. The workshop will cover:
Reservations are required. Additional information on other Career and Postdoctoral Services Office resources is available on the department’s website.
The
annual New Faculty Happy Hour; welcoming recently arrived faculty members to
the California campus, will be held Thursday, March 14, 5 PM in the Faculty
Club Tennis room. The event is sponsored jointly by the Network for Women in
Science, the Society of Fellows and the TSRI graduate program.
Open to the entire TSRI community, the event provides an informal setting for
interaction and networking. Refreshments and Amazon gift card raffle prizes
will be offered; no RSVP required. New faculty members interested in attending
are asked to contact Laurie Gay at ljgay@scripp.edu or x4-2720.
The
two-day South Florida Academic Leadership Symposium, offering training on how
to run an innovative and productive research lab, will be held Friday, March
15, and Saturday, March 16, 8:30 AM to 4:30 PM, at the Max Planck Florida
Institute in Jupiter.
The course is designed for postdocs and junior faculty in the biomedical,
physical and life sciences from South Florida institutes, including TRSI, Max
Planck, Vaccine and Gene Therapy Institute of Florida, Florida Atlantic
University, Torrey Pines Institute for Molecular Studies, Sanford-Burnham Medical
Research Institute and University of Miami. The program is also open to
graduate students and staff scientists.
Similar to the six-year program that has been presented in San Diego, symposium
topics will include teambuilding, communications, leadership styles, time management,
lab set-up, tenure issues and science marketing.
Course fees are: $25, graduate students; $50, postdocs; $75, junior faculty and
staff scientists. Registration and additional details are available at http://sfals2013.eventbrite.com. For
further information, contact Michael Matrone at matrone@scripps.edu or (858)
784-9391.
How
to secure grants and faculty promotions is the focus of the next Academic
Careers Roundtable discussion, to be held Wednesday, March 20, noon to 1 PM, in
room B252 on the Florida campus.
Michael Farzan, TSRI professor in the Department of Infectious Diseases is the
faculty guest for the discussion, “Negotiating Grants and Academic Promotions.”
Farzan joined TRSI in 2012 from Harvard Medical School, where he served on the
faculty for 13 years.
Presented by the Career and Postdoctoral Services Office, the roundtable series
is formatted as an informal conversation with students, postdocs and a featured
guest. Lunch will be served; reservations are required.
Three
female scientists will share insights and advice from their non-research career
paths at the next Florida campus Network for Women in Science chapter meeting,
scheduled for Wednesday, March 20, 4 to 5 PM in room B158.
The speakers are Dawn Johnson, senior director of Scripps Florida operations, Deborah
Leach-Scampavia, who leads the campus’s education and outreach programs, and Rosie
Albarran Zeckle, education researcher.
For details on other Florida campus NWiS activities and resources, visit the
group’s website. To sign up
for NWiS e-mails, contact Briana Weiser, graduate student in the Tellinghuisen
lab and event organizer, at (561) 228-2444 or bweiser@scripps.edu.
Send comments to: mikaono[at]scripps.edu