PubMed Link



R. F. Pauszek, R. Lamichhane, A. Rajkarnikar Singh, D. P. Millar, "Single-molecule view of coordination in a multi-functional DNA polymerase" bioRxiv 2020.08.12.248633;
doi: https://doi.org/10.1101/2020.08.12.248633.


1. R. L. Lamichhane, J. Liu, S. Katritch, K. L. White, R. C. Stevens, K. Wüthrich and D. P. Millar, “Biased Signaling of the G Protein-Coupled Receptor β2AR is Governed by Conformational Exchange Kinetics”, Structure 28, 371-377 (2020). PMID: 31978323.


2. S. Kömürlü, M. Bradley, N. Smolin, S. Imam, R.F. Pauszek III, S. L. Robia, D. Millar, E. E. Nakayama, T. Shioda and E. M. Campbell, "Defects in Assembly Explain Reduced Antiviral Activity of the G249D Polymorphism in Human TRIM5α". PLoS One, 14, e0212888 (2019). PMID:30889178.


3. J. A. Hammond, L. Zhou, R. Lamichhane, H. Y. Chu, D. P. Millar, L. Gerace and J. R. Williamson, "A Survey of DDX21 Activity During Rev/RRE Complex Formation". J. Mol. Biol. 430, 537-553 (2018). PMID: 28705764.


4. R. L. Lamichhane, J. A., Hammond, R. Pauszek, R. Anderson, E. J. C. van der Schans, E. Pedron, J. R. Williamson and D. P. Millar, "A DEAD-Box Protein Acts Through RNA to Promote HIV-1 Rev-RRE Assembly”, Nucleic Acids Research, 45, 4632-4641 (2017). PMID: 28379444.


5. J. A., Hammond, R. L. Lamichhane, D. P. Millar and J. R. Williamson, "A DEAD-Box Helicase Mediates an RNA Structural Transition in the HIV-1 Rev Response Element”, J. Mol. Biol. 429, 697-714 (2017). PMID: 28153748.


6. R. L. Lamichhane, S. Mukherjee, N. Smolin, R. F. Pauszek III, M. Bradley, J. Sastri, S. L. Robia, D. P. Millar and E. M. Campbell, "Dynamic Conformational Changes in the Rhesus TRIM5α Dimer Dictate the Potency of HIV-1 Restriction", Virology 500, 161-168 (2017). PMID: 27821283.


7. T. Lavergne, R. Lamichhane, D.A. Malyshev, Z. Li, L. Li, E. Sperling, J. R. Williamson, D. P. Millar, and F. E. Romesberg “FRET characterization of complex conformational changes in a large 16S ribosomal RNA fragment site-specifically labeled using unnatural base pairs”, ACS Chem. Biol. 11, 1347-1353 (2016).


8. R. Lamichhane, J. J. Liu, G. Pljevaljcic, K. L. White, E. van der Schans, V. Katritch, R. C. Stevens, K. Wüthrich and D. P. Millar, “Single-Molecule View of Basal Activity and Activation Mechanisms of the G Protein-Coupled Receptor 2AR”, Proc. Natl. Acad. Sci. USA 112, 14254-14259 (2015).


9. R. Lamichhane, S.Y. Berzhna, J.P. Gill, E. Van der Schans and D.P. Millar, “Dynamics of site switching in DNA polymerase”, J. Am. Chem. Soc. 135, 4735-4742 (2013).


10. W. Ridgeway, D. P. Millar and J. R. Williamson, “Quantitation of Ten 30S Ribosomal Assembly Intermediates using Fluorescence Triple Correlation Spectroscopy”, Proc. Natl. Acad. Sci. USA, 109, 13614-13619 (2012).


11. S.Y. Berzhna, J.P. Gill, R. Lamichhane and D. P. Millar, "Single-Molecule Förster Resonance Energy Transfer Reveals an Innate Fidelity Checkpoint in DNA Polymerase I ", J. Am. Chem. Soc. 134, 11261-1268 (2012).


12. D. Hoffmann, D. Schwark, C. Banning, M. Brenner, L. Mariyanna, M. Krepstakies, M. Schindler, D.P. Millar and J.R. Hauber, "Formation of Trans-Activation Competent HIV-1 Rev:RRE Complexes Requires the Recruitment of Multiple Protein Activation Domains".  PLOS One 7, e38305-e3820 (2012).


13. W. Ridgeway, D. P. Millar and J. R. Williamson, "The Spectroscopic Basis of Fluorescence Triple Correlation Spectroscopy", Jour. of Phys. Chem. B 116, 1908-1919 (2012).


14. R. M. Robertson-Anderson, J. Wang, S. P. Edgcomb, A. B. Carmel, J. R. Williamson and D. P. Millar, "Single-Molecule Studies Reveal that DEAD Box Protein DDX1 Promotes Oligomerization of HIV-1 Rev on the Rev Response Element", Jour. Mol. Biol. 410, 959-971 (2011).


15. S. J. Pond, W. Ridgeway, R. Robertson, J. Wang and D. P. Millar, "HIV-1 Rev Protein Assembles on Viral RNA One Molecule at a Time", Proc. Natl. Acad. Sci. USA 106, 1404-1408 (2009).


16. E. W. Debler, G. F. Kaufmann, M. M. Meijler, A. Heine, J. M. Mee, G. Pljevaljcic, A. J. De Bilio, P. G. Schultz, D. P. Millar, K. D. Janda, I. A. Wilson, H. B. Gray and R. L. Lerner, "Deeply Inverted Electron-Hole Recombination in an Antibody-Stilbene Complex", Science 319, 1232-1235 (2008).