The Mayford Laboratory

Publications

Colvis CM, Pollock JD, Goodman RH, Impey S, Dunn J, Mandel G, Champagne FA, Mayford M, Korzus E, Kumar A, Renthal W, Theobald DEH and Nestler E. (2005) Epigenetic Mechanisms and Gene Networks in the Nervous System. J. Neurosci., 25(45):10379-10389. PubMed - No Abstract

Limbäck-Stokin K, Korzus E, Nagaoka-Yasuda R and Mayford M. (2004) Nuclear Calcium/Calmodulin Regulates Memory Consolidation. J. Neurosci., 24(48):10858-10867. [PubMed Abstract]

Korzus E, Rosenfeld MG and Mayford M. (2004) CBP Histone Acetyltransferase Activity is Critical Component of Memory Consolidation. Neuron, 42, 961-972. [PubMed Abstract]

Miller S, Yasuda M, Coats JK, Jones Y, Martone ME and Mayford M. (2002) Disruption of Dendritic Translation of CaMKII Impairs Stabilization of Synaptic Plasticity and Memory Consolidation. Neuron, 36, 507-519. [PubMed Abstract]

Bejar R, Yasuda R, Krugers H, Hood K and Mayford M. (2002) Transgenic CAMKII Activation: Dose Dependent Effects on Synaptic Plasticity, Learning, and Memory in Mice. J. Neurosci., 22, 5719-5726. [PubMed Abstract]

Glazewski S, Bejar R, Mayford M and Fox K. (2001) The effect of autonomous alpha-CamKII expression on sensory responses and experience-dependent plasticity in mouse barrel cortex. Neuropharmacology . 41, 771-8. [PubMed Abstract]

Krestel HE, Mayford M, Seeburg PH and Sprengel R. (2001) A GFP-equipped bidirectional expression module well suited for monitoring tetracycline-regulated gene expression in mouse. Nucleic Acids Res, 29:E39. [PubMed Abstract]

Sandberg R, Yasuda R, Pankratz DG, Carter TA, Del Rio JA, Wodicka L, Mayford M, Lockhart DJ and Barlow C. (2000) Regional and strain-specific gene expression mapping in the adult mouse brain. Proc Natl Acad Sci U S A, 97:11038-43. [PubMed Abstract]

Wiedenmayer C, Myers M, Mayford M and Barr G. (2000) Olfactory based spatial learning in neonatal mice and its dependence on CaMKII. Neuro. 5, 1051-1055. [PubMed Abstract]

Mayford M and Kandel ER. (1999) Genetic approaches to memory storage. Trends Genet., 15, 11, 463-470. [PubMed Abstract]

Mansuy IM, Winder DG, Moallem TM, Osman M, Mayford M, Hawkins RD and Kandel ER. (1998) Inducible and reversible gene expression with the rtTA system for the study of memory. Neuron 21, 257-265. [PubMed Abstract]

Mansuy IM, Mayford M, Jacob B, Kandel ER and Bach ME. (1998) Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory. Cell 92, 39-50. [PubMed Abstract]

Mayford M, Mansuy IM, Muller RU and Kandel ER. (1997) Memory and behavior: A second generation of genetically modified mice. Curr. Biol. 7, 580-589. [PubMed Abstract]

Kojima N, Wang J, Mansuy IM, Grant SGN, Mayford M and Kandel ER. (1997) Rescuing impairment of long-term potentiation in fyn-deficient mice by introducing a Fyn transgene Proc. Natl. Acad. Sci. USA 94, 4761-4765. [PubMed Abstract]

Mayford M, Bach ME and Kandel ER. (1996) CaMKII function in the nervous system explored from a genetic perspective. Cold Spring Harbor Symp. 59, 219-223.

Tsien JZ, Chen DF, Gerber D, Tom C, Mercer E, Anderson DJ, Mayford M, Kandel ER and Tonegawa S. (1996) Subregion- and cell type-restricted gene knockout in mouse brain. Cell 87, 1317-1326. [PubMed Abstract]

Rotenberg A, Mayford M, Hawkins RD, Kandel ER and Muller R. (1996) Mice expressing activated CaMKII lack low frequency LTP and do not form stable place cells in the CA1 region of the hippocampus. Cell 87, 1351-1361. [PubMed Abstract]

Mayford M, Bach ME, Huang Y-Y, Wang L, Hawkins RD and Kandel ER. (1996) Control of memory formation through regulated expression of a CaMKII transgene. Science 274, 1678-1683. [PubMed Abstract]

Mayford M, Baranes D, Podsypanina K and Kandel ER. (1996) The 3' untranslated region of CaMKIIa is a cis-acting signal for the localization and translation of mRNA in dendrites. Proc. Natl. Acad. Sci. USA 93, 13250-13255. [PubMed Abstract]

Bach M-E, Hawkins RD, Osman M, Kandel ER and Mayford M. (1995) Impairment of spatial but not contextual memory in CaMKII mutant mice with a selective loss of hippocampal LTP in the range of the theta frequency. Cell 81, 905-915. [PubMed Abstract]

Mayford M, Wang J, Kandel ER and O'Dell T. (1995) CaMKII Regulates the frequency-response function of hippocampal synapses for the production of both long-term depression and long-term potentiation. Cell 81, 891-904. [PubMed Abstract]

Mayford M, Barzilai A, Keller F, Schacher S and Kandel ER. (1992) Modulation of an NCAM-related cell adhesion molecule with long-term synaptic plasticity in Aplysia. Science 256, 638-644. [PubMed Abstract]

Schacher S, Glanzman A, Barzilai A, Dash P, Grant SGN, Keller F, Mayford M and Kandel ER. (1991) Long-term facilitation in Aplysia: Persistent phosphorylation and structural changes. Cold Spring Harbor Symp. Quant. Biol. 55, 187-202.

Mayford M and Weisblum B. (1990) Variable efficiency of induction by macrolide-lincosamide-streptogramin antibiotics resulting from systematic alterations in the ermC leader peptide. J. Bacteriol. 172, 3772-3779.

Mayford M and Weisblum B. (1989) Conformational alterations in the ermC transcript in vivo during induction. EMBO J. 8, 4307-4314. [PubMed Abstract]

Mayford M and Weisblum B. (1989) The ermC leader peptide: Amino acid sequence critical for induction by translational attenuation. J. Mol. Biol. 206, 69-79. [PubMed Abstract]

Mayford M and Weisblum B. (1985) Messenger RNA from Staphylococcus aureus that specifies macrolide-lincosamide-streptogramin resistance: Demonstration of its conformation and of the leader peptide it encodes. J. Mol. Biol. 185, 769-780. [PubMed Abstract]

Invited Articles

Miller S and Mayford M. (1999) Cellular and molecular mechanisms of memory: The LTP connection. Curr. Opin. Genet. Dev. 9, 333-337.

Mansuy I, Mayford M and Kandel ER. (1999) Regulated temporal and spatial expression of mutants of CaMKII and calcineurin with the tetracycline-controlled transactivator (tTA) and reverse tTA (rtTA) systems. Handbook of Molecular-Genetic Techniques for Brain and Behavior Research (Techniques in the Behavioral and Neural Sciences, 13, chapter 3.1.4.

Mayford M. (1996) Genetic studies of CaMKII function in the nervous system. In Gene targeting and new developments in neurobiology, eds. S. Nakanishi, A. J. Silva, S. Aizawa and M. Katsuki, pp. 239-250. Tokyo: Karger.

Mayford M. (1996) Ca2+/Calmodulin dependent protein kinase and neuronal function. In Protein phosphorylation, ed. F. Marks, pp. 149-178. Weinheim: Verlag Chemie.

Mayford M, Able T and Kandel ER. (1995) Transgenic approaches to cognition. Curr. Opin. in Neuro. 5, 141-148.

Mayford M and Kandel ER. (1994) Molecular mechanisms of synaptic plasticity. Biomed Res. 15 Suppl. 1, 57-60.