Tumor Immunology

Our immune system has the capability to eliminate cancer cells, and thus protect us from cancer. However, two major problems are limiting efficient elimination of cancer cells through our immune system: i) anti-tumor CD8 T cells might become exhausted or not kill sufficiently well, and ii) regulatory CD4 T cells might suppress potential protective immune responses. In order to better understand these problems, the Kirak lab is developing novel T cell models by using Somatic Cell Nuclear Transfer (SCNT or NT).

...to be continued