Publications
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1. Olsen, C. A., and Ghadiri, M. R. "Discovery of potent and selective histone deacetylase inhibitors via focused combinatorial libraries of cyclic alpha-3-beta-tetrapeptides." J. Med. Chem. 2009, 52, 7836-7846.
http://pubs.acs.org/doi/full/10.1021/jm900850t
http://www.ncbi.nlm.nih.gov/pubmed/197058462. Ura, Y., Al-Sayah, M., Montenegro, J., Beierle, J. M., Leman, L. J., and Ghadiri, M. R. "Dynamic polythioesters via ring-opening polymerization of 1,4-thiazine-2,5-diones." Org. Biomol. Chem. 2009, 7, 2878-2884.
http://www.rsc.org/publishing/journals/OB/article.asp?doi=b903612a
http://www.ncbi.nlm.nih.gov/pubmed/195822973. Ura, Y., Beierle, J. M., Leman, L. J., Orgel, L. E., and Ghadiri, M. R. "Self-assembling sequence-adaptive peptide nucleic acids." Science 2009, 325, 73-77.
http://www.scienceonline.org/cgi/content/abstract/325/5936/73
http://www.ncbi.nlm.nih.gov/pubmed/19520909?dopt=Abstract4. Motiei, L., Rahimipour, S., Thayer, D. A., Wong, C.-H., and Ghadiri, M. R. "Antibacterial cyclic DL-alpha-glycopeptides." Chem. Commun. 2009, 3693-3695.
http://www.rsc.org/publishing/journals/CC/article.asp?doi=b902455g
http://www.ncbi.nlm.nih.gov/pubmed/195572515. Horne, W. S., Olsen, C. A., Beierle, J. M., Montero, A., and Ghadiri, M. R. "Probing the bioactive conformation of an archetypal natural product HDAC inhibitor with conformationally homogeneous triazole-modified cyclic tetrapeptides." Angew. Chem., Int. Ed. 2009, 48, 4718-4724.
http://www3.interscience.wiley.com/cgi-bin/fulltext/122243285/HTMLSTART
http://www.ncbi.nlm.nih.gov/pubmed/192673806. Beierle, J. M., Horne, W. S., van Maarseveen, J. H., Waser, B., Reubi, J. C., and Ghadiri, M. R. "Conformationally homogeneous heterocyclic pseudotetrapeptides as three-dimensional scaffolds for rational drug design: receptor-selective somatostatin analogues." Angew. Chem., Int. Ed. 2009, 48, 4725-4729.
http://www3.interscience.wiley.com/cgi-bin/fulltext/122240965/HTMLSTART
http://www.ncbi.nlm.nih.gov/pubmed/192665067. Picuri, J. M., Frezza, B. M., and Ghadiri, M. R. "Universal translators for nucleic acid diagnosis." J. Am. Chem. Soc. 2009, 131, 9368-9377.
http://pubs.acs.org/doi/full/10.1021/ja902490x
http://www.ncbi.nlm.nih.gov/pubmed/195661018. Montero, A., Beierle, J. M., Olsen, C. A., and Ghadiri, M. R. "Design, synthesis, biological evaluation, and structural characterization of potent histone deacetylase inhibitors based on cyclic alpha/beta-tetrapeptide architectures." J. Am. Chem. Soc. 2009, 131, 3033-3041.
http://pubs.acs.org/doi/full/10.1021/ja809508f
http://www.ncbi.nlm.nih.gov/pubmed/192392709. Voelcker, N. H., Alfonso, I., and Ghadiri, M. R. "Catalyzed oxidative corrosion of porous silicon used as an optical transducer for ligand-receptor interactions." ChemBioChem 2008, 9, 1776-1786.
http://www3.interscience.wiley.com/cgi-bin/fulltext/120118539/HTMLSTART
http://www.ncbi.nlm.nih.gov/pubmed/1857644910. Voelcker, N. H., Guckian, K. M., Saghatelian, A., and Ghadiri, M. R. "Sequence-addressable DNA logic." Small 2008, 4, 427-431.
http://www3.interscience.wiley.com/cgi-bin/fulltext/117943315/HTMLSTART
http://www.ncbi.nlm.nih.gov/pubmed/1835055411. Cheng, G., Montero, A., Gastaminza, P., Whitten-Bauer, C., Wieland, S. F., Isogawa, M., Fredericksen, B., Selvarajah, S., Gallay, P. A., Ghadiri, M. R., and Chisari, F. V. "A virocidal amphipathic alpha-helical peptide that inhibits hepatitis C virus infection in vitro." Proc. Natl. Acad. Sci. U. S. A. 2008, 105, 3088-3093.
http://www.pnas.org/content/105/8/3088.long
http://www.ncbi.nlm.nih.gov/pubmed/1828702312. Huang, Z.-Z., Leman, L. J., and Ghadiri, M. R. "Biomimetic catalysis of diketopiperazine and dipeptide syntheses." Angew. Chem., Int. Ed. 2008, 47, 1758-1761.
http://www3.interscience.wiley.com/cgi-bin/fulltext/117892450/HTMLSTART
http://www.ncbi.nlm.nih.gov/pubmed/1821366613. Cockroft, S. L., Chu, J., Amorin, M., and Ghadiri, M. R. "A single-molecule nanopore device detects DNA polymerase activity with single-nucleotide resolution." J. Am. Chem. Soc. 2008, 130, 818-820.
http://pubs.acs.org/doi/full/10.1021/ja077082c
http://www.ncbi.nlm.nih.gov/pubmed/1816605414. Frezza, B. M., Cockroft, S. L., and Ghadiri, M. R. "Modular multi-level circuits from immobilized DNA-based logic gates." J. Am. Chem. Soc. 2007, 129, 14875-14879.
http://pubs.acs.org/doi/full/10.1021/ja0710149
http://www.ncbi.nlm.nih.gov/pubmed/1799473415. Gianneschi, N. C., and Ghadiri, M. R. "Design of molecular logic devices based on a programmable DNA-regulated semisynthetic enzyme." Angew. Chem., Int. Ed. 2007, 46, 3955-3958.
http://www3.interscience.wiley.com/cgi-bin/fulltext/114209550/HTMLSTART
http://www.ncbi.nlm.nih.gov/pubmed/1742790016. Fletcher, J. T., Finlay, J. A., Callow, M. E., Callow, J. A., and Ghadiri, M. R. "A combinatorial approach to the discovery of biocidal six-residue cyclic D,L-alpha-peptides against the bacteria methicillin-resistant Staphylococcus aureus (MRSA) and E. coli and the biofouling algae ulva linza and Navicula perminuta." Chem.–Eur. J. 2007, 13, 4008-4013.
http://www3.interscience.wiley.com/cgi-bin/fulltext/114123285/HTMLSTART
http://www.ncbi.nlm.nih.gov/pubmed/1730459817. Leman, L. J., Weinberger, D. A., Huang, Z.-Z., Wilcoxen, K. M., and Ghadiri, M. R. "Functional and mechanistic analyses of biomimetic aminoacyl transfer reactions in de novo designed coiled coil peptides via rational active site engineering." J. Am. Chem. Soc. 2007, 129, 2959-2966.
http://pubs.acs.org/doi/full/10.1021/ja068052x
http://www.ncbi.nlm.nih.gov/pubmed/1730241718. Wilcoxen, K. M., Leman, L. J., Weinberger, D. A., Huang, Z.-Z., and Ghadiri, M. R. "Biomimetic catalysis of intermodular aminoacyl transfer." J. Am. Chem. Soc. 2007, 129, 748-749.
http://pubs.acs.org/doi/full/10.1021/ja067124h
http://www.ncbi.nlm.nih.gov/pubmed/1724379619. Yadav, M. K., Leman, L. J., Price, D. J., Brooks, C. L., III, Stout, C. D., and Ghadiri, M. R. "Coiled coils at the edge of configurational heterogeneity. Structural analyses of parallel and antiparallel homotetrameric coiled coils reveal configurational sensitivity to a single solvent-exposed amino acid substitution." Biochemistry 2006, 45, 4463-4473.
http://pubs.acs.org/doi/full/10.1021/bi060092q
http://www.ncbi.nlm.nih.gov/pubmed/1658418220. Ashkenasy, N., Horne, W. S., and Ghadiri, M. R. "Design of self-assembling peptide nanotubes with delocalized electronic states." Small 2006, 2, 99-102.
http://www3.interscience.wiley.com/cgi-bin/fulltext/112137030/HTMLSTART
http://www.ncbi.nlm.nih.gov/pubmed/1719356321. Leman, L. J., Orgel, L. E., and Ghadiri, M. R. "Amino acid dependent formation of phosphate anhydrides in water mediated by carbonyl sulfide." J. Am. Chem. Soc. 2006, 128, 20-21.
http://pubs.acs.org/doi/full/10.1021/ja056036e
http://www.ncbi.nlm.nih.gov/pubmed/1639010122. Nicolaou, K. C., Zak, M., Rahimipour, S., Estrada, A. A., Lee, S. H., O'Brate, A., Giannakakou, P., and Ghadiri, M. R. "Discovery of a biologically active thiostrepton fragment." J. Am. Chem. Soc. 2005, 127, 15042-15044.
http://pubs.acs.org/doi/full/10.1021/ja0552803
http://www.ncbi.nlm.nih.gov/pubmed/1624864023. Van Maarseveen, J. H., Horne, W. S., and Ghadiri, M. R. "Efficient route to C2 symmetric heterocyclic backbone modified cyclic peptides." Org. Lett. 2005, 7, 4503-4506.
http://pubs.acs.org/doi/full/10.1021/ol0518028
http://www.ncbi.nlm.nih.gov/pubmed/1617856924. Dartois, V., Sanchez-Quesada, J., Cabezas, E., Chi, E., Dubbelde, C., Dunn, C., Granja, J., Gritzen, C., Weinberger, D., Ghadiri, M. R., and Parr, T. R., Jr. "Systemic antibacterial activity of novel synthetic cyclic peptides." Antimicrob. Agents Chemother. 2005, 49, 3302-3310.
http://aac.asm.org/cgi/content/full/49/8/3302?view=long&pmid=16048940
http://www.ncbi.nlm.nih.gov/pubmed/1604894025. Horne, W. S., Wiethoff, C. M., Cui, C., Wilcoxen, K. M., Amorin, M., Ghadiri, M. R., and Nemerow, G. R. "Antiviral cyclic D, L-alpha-peptides: Targeting a general biochemical pathway in virus infections." Bioorg. Med. Chem. 2005, 13, 5145-5153.
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TF8-4GHRBY0-4&_
user=1018416&_coverDate=09%2F01%2F2005&_rdoc=19&_fmt=high&_orig=browse&_srch= doc-info(%23toc%235220% 232005%23999869982%23602846%23FLA%23display%23Volume)&_cdi=5220&_ sort=d&_docanchor=&_ ct=42&_acct=C000050428&_version=1&_urlVersion=0&_userid= 1018416&md5=72bd55cdf4dd27a7b70f9e6ad0988ed0
http://www.ncbi.nlm.nih.gov/pubmed/1599361126. Yadav, M. K., Redman, J. E., Leman, L. J., Alvarez-Gutierrez, J. M., Zhang, Y., Stout, C. D., and Ghadiri, M. R. "Structure-based engineering of internal cavities in coiled-coil peptides." Biochemistry 2005, 44, 9723-9732.
http://pubs.acs.org/doi/full/10.1021/bi050742a
http://www.ncbi.nlm.nih.gov/pubmed/1600835727. Ashkenasy, N., Sanchez-Quesada, J., Bayley, H., and Ghadiri, M. R. "Recognizing a single base in an individual DNA strand: A step toward DNA sequencing in nanopores." Angew. Chem., Int. Ed. 2005, 44, 1401-1404.
http://www3.interscience.wiley.com/cgi-bin/fulltext/109869340/HTMLSTART
http://www.ncbi.nlm.nih.gov/pubmed/1566641928. Horne, W. S., Ashkenasy, N., and Ghadiri, M. R. "Modulating charge transfer through cyclic D,L-alpha-peptide self-assembly." Chem.--Eur. J. 2005, 11, 1137-1144.
http://www3.interscience.wiley.com/cgi-bin/fulltext/109861319/HTMLSTART
http://www.ncbi.nlm.nih.gov/pubmed/1562412429. Horne, W. S., Yadav, M. K., Stout, C. D., and Ghadiri, M. R. "Heterocyclic peptide backbone modifications in an alpha-helical coiled coil." J. Am. Chem. Soc. 2004, 126, 15366-15367.
http://pubs.acs.org/doi/full/10.1021/ja0450408
http://www.ncbi.nlm.nih.gov/pubmed/1556314830. Leman, L., Orgel, L., and Ghadiri, M. R. "Carbonyl sulfide-mediated prebiotic formation of peptides." Science 2004, 306, 283-286.
http://www.sciencemag.org/cgi/content/full/306/5694/283
http://www.ncbi.nlm.nih.gov/pubmed/1547207731. Ashkenasy, G., and Ghadiri, M. R. "Boolean logic functions of a synthetic peptide network." J. Am. Chem. Soc. 2004, 126, 11140-11141.
http://pubs.acs.org/doi/full/10.1021/ja046745c
http://www.ncbi.nlm.nih.gov/pubmed/1535508132. Ashkenasy, G., Jagasia, R., Yadav, M., and Ghadiri, M. R. "Design of a directed molecular network." Proc. Natl. Acad. Sci. U. S. A. 2004, 101, 10872-10877.
http://www.pnas.org/content/101/30/10872.long
http://www.ncbi.nlm.nih.gov/pubmed/1525659633. Sanchez-Quesada, J., Saghatelian, A., Cheley, S., Bayley, H., and Ghadiri, M. R. "Single DNA rotaxanes of a transmembrane pore protein." Angew. Chem., Int. Ed. 2004, 43, 3063-3067.
http://www3.interscience.wiley.com/cgi-bin/fulltext/108061229/HTMLSTART
http://www.ncbi.nlm.nih.gov/pubmed/1518848234. Horne, W. S., Stout, C. D., and Ghadiri, M. R. "A heterocyclic peptide nanotube." J. Am. Chem. Soc. 2003, 125, 9372-9376.
http://pubs.acs.org/doi/full/10.1021/ja034358h
http://www.ncbi.nlm.nih.gov/pubmed/1288996635. Saghatelian, A., Voelcker, N. H., Guckian, K. M., Lin, V. S. Y., and Ghadiri, M. R. "DNA-based photonic logic gates: AND, NAND, and INHIBIT." J. Am. Chem. Soc. 2003, 125, 346-347.
http://pubs.acs.org/doi/full/10.1021/ja029009m
http://www.ncbi.nlm.nih.gov/pubmed/1251714236. Saghatelian, A., Guckian, K. M., Thayer, D. A., and Ghadiri, M. R. "DNA detection and signal amplification via an engineered allosteric enzyme." J. Am. Chem. Soc. 2003, 125, 344-345.
http://pubs.acs.org/doi/full/10.1021/ja027885u
http://www.ncbi.nlm.nih.gov/pubmed/1251714137. Redman, J. E., Wilcoxen, K. M., and Ghadiri, M. R. "Automated mass spectrometric sequence determination of cyclic peptide library members." J. Comb. Chem. 2003, 5, 33-40.
http://pubs.acs.org/doi/full/10.1021/cc0200639
http://www.ncbi.nlm.nih.gov/pubmed/1252383238. Redman, J. E., and Ghadiri, M. R. "Synthesis of photoactive p-azidotetrafluorophenylalanine containing peptide by solid-phase Fmoc methodology." Org. Lett. 2002, 4, 4467-4469.
http://pubs.acs.org/doi/full/10.1021/ol026998f
http://www.ncbi.nlm.nih.gov/pubmed/1246591439. Sanchez-Quesada, J., Isler, M. P., and Ghadiri, M. R. "Modulating ion channel properties of transmembrane peptide nanotubes through heteromeric supramolecular assemblies." J. Am. Chem. Soc. 2002, 124, 10004-10005.
http://pubs.acs.org/doi/full/10.1021/ja025983%2B
http://www.ncbi.nlm.nih.gov/pubmed/1218866140. Fernandez-Lopez, S., Kim, H.-S., Choi, E. C., Delgado, M., Granja, J. R., Khasanov, A., Kraehenbuehl, K., Long, G., Weinberger, D. A., Wilcoxen, K. M., and Ghadiri, M. R. "Antibacterial agents based on the cyclic D,L-alpha-peptide architecture." Nature 2001, 412, 452-456.
http://www.nature.com/nature/journal/v412/n6845/full/412452a0.html
http://www.ncbi.nlm.nih.gov/pubmed/1147332241. Sanchez-Quesada, J., Kim, H. S., and Ghadiri, M. R. "A synthetic pore-mediated transmembrane transport of glutamic acid." Angew. Chem., Int. Ed. 2001, 40, 2503-2506.
http://www3.interscience.wiley.com/cgi-bin/fulltext/84503191/HTMLSTART
http://www.ncbi.nlm.nih.gov/pubmed/1144367942. Bong, D. T., and Ghadiri, M. R. "Chemoselective Pd(0)-catalyzed peptide coupling in water." Org. Lett. 2001, 3, 2509-2511.
http://pubs.acs.org/doi/full/10.1021/ol016169e
http://www.ncbi.nlm.nih.gov/pubmed/1148304743. Bong, D. T., and Ghadiri, M. R. "Self-assembling cyclic peptide cylinders as nuclei for crystal engineering." Angew. Chem., Int. Ed. 2001, 40, 2163-2166.
http://www3.interscience.wiley.com/journal/82003461/abstract
http://www.ncbi.nlm.nih.gov/pubmed/1143347644. Bong, D. T., Clark, T. D., Granja, J. R., and Ghadiri, M. R. "Self-assembling organic nanotubes." Angew. Chem., Int. Ed. 2001, 40, 988-1011.
http://www3.interscience.wiley.com/cgi-bin/fulltext/78002565/HTMLSTART
http://www.ncbi.nlm.nih.gov/pubmed/1126806245. Saghatelian, A., Yokobayashi, Y., Soltani, K., and Ghadiri, M. R. "A chiroselective peptide replicator." Nature 2001, 409, 797-801.
http://www.nature.com/nature/journal/v409/n6822/full/409797a0.html
http://www.ncbi.nlm.nih.gov/pubmed/1123698846. Kennan, A. J., Haridas, V., Severin, K., Lee, D. H., and Ghadiri, M. R. "A de novo designed peptide ligase: a mechanistic investigation." J. Am. Chem. Soc. 2001, 123, 1797-1803.
http://pubs.acs.org/doi/full/10.1021/ja991266c
http://www.ncbi.nlm.nih.gov/pubmed/1145679647. Sanchez-Quesada, J., Ghadiri, M. R., Bayley, H., and Braha, O. "Cyclic Peptides as Molecular Adapters for a Pore-Forming Protein." J. Am. Chem. Soc. 2000, 122, 11757-11766.
http://pubs.acs.org/doi/full/10.1021/ja002436k
48. Bong, D. T., Janshoff, A., Steinem, C., and Ghadiri, M. R. "Membrane partitioning of the cleavage peptide in flock house virus." Biophys. J. 2000, 78, 839-845.
http://www.cell.com/biophysj/retrieve/pii/S0006349500766410
http://www.ncbi.nlm.nih.gov/pubmed/1065379649. Bong, D. T., Steinem, C., Janshoff, A., Johnson, J. E., and Ghadiri, M. R. "A highly membrane- active peptide in Flock House virus: implications for the mechanism of nodavirus infection." Chem. Biol. 1999, 6, 473-481.
http://www.cell.com/chemistry-biology/abstract/S1074-5521(99)80065-9
50. Vollmer, M. S., Clark, T. D., Steinem, C., and Ghadiri, M. R. "Photoswitchable hydrogen-bonding in self-organized cylindrical peptide systems." Angew. Chem., Int. Ed. 1999, 38, 1598-1601.
http://www3.interscience.wiley.com/journal/61501359/abstract
51. Granja, J. R., and Ghadiri, M. R. "Self-assembling peptide nanotubes." NATO ASI Ser., Ser. C 1999, 526, 61-66.
52. Steinem, C., Janshoff, A., Vollmer, M. S., and Ghadiri, M. R. "Reversible photoisomerization of self-organized cylindrical peptide assemblies at air-water and solid interfaces." Langmuir 1999, 15, 3956-3964.
http://pubs.acs.org/doi/full/10.1021/la981624%2B
53. Janshoff, A., Bong, D. T., Steinem, C., Johnson, J. E., and Ghadiri, M. R. "An animal virus-derived peptide switches membrane morphology: possible relevance to nodaviral transfection processes." Biochemistry 1999, 38, 5328-5336.
http://pubs.acs.org/doi/full/10.1021/bi982976i
http://www.ncbi.nlm.nih.gov/pubmed/1022031954. Clark, T. D., Kobayashi, K., and Ghadiri, M. R. "Covalent capture and stabilization of cylindrical beta-sheet peptide assemblies." Chem.--Eur. J. 1999, 5, 782-792.
http://www3.interscience.wiley.com/journal/40003319/abstract
55. Rapaport, H., Kim, H. S., Kjaer, K., Howes, P. B., Cohen, S., Als-Nielsen, J., Ghadiri, M. R., Leiserowitz, L., and Lahav, M. "Crystalline cyclic peptide nanotubes at interfaces." J. Am. Chem. Soc. 1999, 121, 1186-1191.
http://pubs.acs.org/doi/full/10.1021/ja982420i
56. Mutz, M. W., Case, M. A., Wishart, J. F., Ghadiri, M. R., and McLendon, G. L. "De novo design of protein function: predictable structure-function relationships in synthetic redox proteins." J. Am. Chem. Soc. 1999, 121, 858-859.
http://pubs.acs.org/doi/full/10.1021/ja9828612
57. Janshoff, A., Dancil, K.-P. S., Steinem, C., Greiner, D. P., Lin, V. S. Y., Gurtner, C., Motesharei, K., Sailor, M. J., and Ghadiri, M. R. "Macroporous p-type silicon Fabry-Perot layers. Fabrication, characterization, and applications in biosensing." J. Am. Chem. Soc. 1998, 120, 12108-12116.
http://pubs.acs.org/doi/full/10.1021/ja9826237
58. Hartgerink, J. D., Clark, T. D., and Ghadiri, M. R. "Peptide nanotubes and beyond." Chem.–Eur. J. 1998, 4, 1367-1372.
http://www3.interscience.wiley.com/journal/5008816/abstract
59. Clark, T. D., Buriak, J. M., Kobayashi, K., Isler, M. P., McRee, D. E., and Ghadiri, M. R. "Cylindrical beta-sheet peptide assemblies." J. Am. Chem. Soc. 1998, 120, 8949-8962.
http://pubs.acs.org/doi/full/10.1021/ja981485i
60. Kim, H. S., Hartgerink, J. D., and Ghadiri, M. R. "Oriented self-assembly of cyclic peptide nanotubes in lipid membranes." J. Am. Chem. Soc. 1998, 120, 4417-4424.
http://pubs.acs.org/doi/full/10.1021/ja9735315
61. Severin, K., Lee, D. H., Martinez, J. A., Vieth, M., and Ghadiri, M. R. "Dynamic error correction in autocatalytic peptide networks." Angew. Chem., Int. Ed. 1998, 37, 126-128.
http://www3.interscience.wiley.com/journal/10004510/abstract
62. Lee, D. H., Severin, K., and Ghadiri, M. R. "Autocatalytic networks: the transition from molecular self-replication to molecular ecosystems." Curr. Opin. Chem. Biol. 1997, 1, 491-496.
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VRX-457KRT5-2H&_ user=1018416 &_coverDate=12%2F31%2F1997&_rdoc=12&_fmt=high&_orig=browse&_ srch=doc-info(%23toc%236246%231997%
23999989995%23286663%23FLP%23display%23Volume)&_cdi=6246&_sort= d&_docanchor=&_ct=28&_acct= C000050428&_version=1&_urlVersion=0&_userid=1018416&md5=934484bddd3210fd12
ef1f4d772ed7ba
http://www.ncbi.nlm.nih.gov/pubmed/966789263. Case, M. A., Ghadiri, M. R., Mutz, M. W., and McLendon, G. L. "Stereoselection in designed three-helix bundle metalloproteins." Chirality 1998, 10, 35-40.
http://www3.interscience.wiley.com/journal/30003335/abstract
http://www.ncbi.nlm.nih.gov/pubmed/947020764. Clark, T. D., Buehler, L. K., and Ghadiri, M. R. "Self-assembling cyclic beta-3-peptide nanotubes as artificial transmembrane ion channels." J. Am. Chem. Soc. 1998, 120, 651-656.
http://pubs.acs.org/doi/full/10.1021/ja972786f
65. Lee, D. H., Severin, K., Yokobayashi, Y., and Ghadiri, M. R. "Emergence of symbiosis in peptide self-replication through a hypercyclic network." Nature 1997, 390, 591-594.
http://www.nature.com/nature/journal/v390/n6660/full/390591a0.html
http://www.ncbi.nlm.nih.gov/pubmed/940368666. Motesharei, K., and Ghadiri, M. R. "Diffusion-limited size-selective ion sensing based on SAM-supported peptide nanotubes." J. Am. Chem. Soc. 1997, 119, 11306-11312.
http://pubs.acs.org/doi/full/10.1021/ja9727171
67. Lin, V. S. Y., Motesharei, K., Dancil, K.-P. S., Sailor, M. J., and Ghadiri, M. R. "A porous silicon-based optical interferometric biosensor." Science 1997, 278, 840-843.
http://www.sciencemag.org/cgi/content/full/278/5339/840
http://www.ncbi.nlm.nih.gov/pubmed/934647868. Severin, K., Lee, D. H., Kennan, A. J., and Ghadiri, M. R. "A synthetic peptide ligase." Nature 1997, 389, 706-709.
http://www.nature.com/nature/journal/v389/n6652/full/389706a0.html
http://www.ncbi.nlm.nih.gov/pubmed/933878069. Severin, K., Lee, D. H., Martinez, J. A., and Ghadiri, M. R. "Peptide self-replication via template-directed ligation." Chem.–Eur. J. 1997, 3, 1017-1024.
http://www3.interscience.wiley.com/journal/112298409/abstract
70. Buriak, J. M., and Ghadiri, M. R. "Self-assembly of peptide based nanotubes."
Mater. Sci. Eng., C 1997, C4, 207-212.
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TXG-3VSKFS2-G&_user=
1018416&_coverDate=04%2F30%2F1997&_rdoc=2&_fmt=high&_orig=browse&_srch=doc-info(%23toc%235590%231997%
23999959995%2359151%23FLP%23display%23Volume)&_cdi= 5590&_sort=d&_docanchor=&_ct=18&_acct=
C000050428&_version=1&_urlVersion=0&_userid=1018416&md5=778c3c5aebc9b1f1ce4
a9439f1d4714e
71. Dawson, P. E., Churchill, M., Ghadiri, M. R., and Kent, S. B. H. "Modulation of reactivity in native chemical ligation through the use of thiol additives." J. Am. Chem. Soc. 1997, 119, 4325-4329.
http://pubs.acs.org/doi/full/10.1021/ja962656r
72. Lee, D. H., and Ghadiri, M. R. "Control of peptide architecture via self-assembly and self-organization processes." Compr. Supramol. Chem. 1996, 9, 451-481.
73. Lee, D. H., Granja, J. R., Martinez, J. A., Severin, K., and Ghadiri, M. R. "A self-replicating peptide." Nature 1996, 382, 525-528.
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74. Hartgerink, J. D., Granja, J. R., Milligan, R. A., and Ghadiri, M. R. "Self-assembling peptide nanotubes." J. Am. Chem. Soc. 1996, 118, 43-50.
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75. Clark, T. D., and Ghadiri, M. R. "Supramolecular design by covalent capture. Design of a peptide cylinder via hydrogen-bond- promoted intermolecular olefin metathesis." J. Am. Chem. Soc. 1995, 117, 12364-12365.
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76. Engels, M., Bashford, D., and Ghadiri, M. R. "Structure and dynamics of self-assembling peptide nanotubes and the channel-mediated water organization and self-diffusion. A molecular dynamics study." J. Am. Chem. Soc.
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77. Kobayashi, K., Granja, J. R., and Ghadiri, M. R. "Beta-sheet peptide architecture: measuring the relative stability of parallel vs. antiparallel beta-sheets." Angew. Chem., Int. Ed. Engl. 1995, 34, 95-98.
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78. Ghadiri, M. R., Kobayashi, K., Granja, J. R., Chadha, R. K., and McRee, D. E. "The structural and thermodynamic basis for the formation of self-assembled peptide nanotubes." Angew. Chem., Int. Ed. Engl. 1995, 34, 93-95.
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79. Granja, J. R., and Ghadiri, M. R. "Channel-mediated transport of glucose across lipid bilayers." J. Am. Chem. Soc. 1994, 116, 10785-10786.
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80. Ghadiri, M. R., Granja, J. R., and Buehler, L. K. "Artificial transmembrane ion channels from self-assembling peptide nanotubes." Nature 1994, 369, 301-304.
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82. Ghadiri, M. R., and Case, M. A. "De novo design of a novel hetero dinuclear metalloprotein with three parallel (bundled) helixes." Angew. Chem., Int. Ed. Engl. 1993, 32, 1594-1597.
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83. Ghadiri, M. R., Granja, J. R., Milligan, R. A., McRee, D. E., and Khazanovich, N. "Self-assembling organic nanotubes based on a cyclic peptide architecture." Nature 1993, 366, 324-327.
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85. Ghadiri, M. R., Soares, C., and Choi, C. "A convergent approach to protein design. Metal ion-assisted spontaneous self-assembly of a polypeptide into a triple-helix bundle protein." J. Am. Chem. Soc. 1992, 114, 825-831.
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86. Ghadiri, M. R., Choi, C., Fernholz, A. K., Ruan, F., Chen, Y., Hopkins, P. B., and Aube, J. "Peptide architecture: design of stabilized alpha-helical metallopeptides." Chemtracts Org. Chem. 1991, 4, 135-139.
87. Ghadiri, M. R., and Fernholz, A. K. "Peptide architecture. Design of stable alpha-helical metallopeptides via a novel exchange-inert ruthenium(III) complex." J. Am. Chem. Soc. 1990, 112, 9633-9635.
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