Publications
| 1990-4 | 1995-9 | 2000 | 2001 | 2002 |
| 2003 | 2004 | 2005 | 2006 | 2007 |
| 2008 | 2009 | 2010 | 2011 | 2012 |
| 2013 |
1. de la Torre, J.C. , E. Wimmer and J. Holland. Very high frequency of reversion to guanidine resistance in clonal fools of guanidine-dependent type 1 poliovirus. J. Virol. 64:664-671, 1990.
2. . Holland , J.J., E. Domingo, J.C. de la Torre and D. Steinhauer. Mutations frequencies at defined single codon sites in vesicular stomatitis virus and poliovirus can be increased only slightly by chemical mutagenesis. J. Virol. 64:3960-3962, 1990.
3. de la Torre, J.C. and J. Holland. RNA virus quasispecies populations can suppress vastly superior mutant progeny. J. Virol. 64:6278-6281, 1990.
4. de la Torre JC, Carbone KM, Lipkin WI. Molecular characterization of the Borna disease agent. Virology. 1990 Dec;179(2):853-6.
5. de la Torre JC, Borrow P, Oldstone MB. Viral persistence and disease: cytopathology in the absence of cytolysis. Br Med Bull. 1991 Oct;47(4):838-51. Review.
6. Holland , J.J., J.C. de la Torre and D. Steinhauer. RNA virus populations as quasispecies. Curr. Top. Microbiol. Immunol. 176:3-20, 1992.
7. de la Torre JC, C Giachetti, B Semler and J Holland. High frequency of single base transitions and extreme frequency of precise multiple-base reversion mutations in poliovirus. Proc. Natl. Acad. Sci. USA 89:2531-2535, 1992.
8. de la Torre JC, Oldstone MB. Selective disruption of growth hormone transcription machinery by viral infection. Proc Natl Acad Sci U S A. 1992 Oct 15;89(20):9939-43.
9. Briese T, de la Torre JC, Lewis A, Ludwig H, Lipkin WI. Borna disease virus, a negative-strand RNA virus, transcribes in the nucleus of infected cells. Proc Natl Acad Sci U S A. 1992 Dec 1;89(23):11486-9.
10. Eddleston M, de la Torre JC, Oldstone MB, Loskutoff DJ, Edgington TS, Mackman N. Astrocytes are the primary source of tissue factor in the murine central nervous system. A role for astrocytes in cerebral hemostasis. J Clin Invest. 1993 Jul;92(1):349-58.
11. Oldstone MB, Tishon A, Eddleston M, de la Torre JC, McKee T, Whitton JL. Vaccination to prevent persistent viral infection. J Virol. 1993 Jul;67(7):4372-8.
12. Tishon A, Eddleston M, de la Torre JC, Oldstone MB. Cytotoxic T lymphocytes cleanse viral gene products from individually infected neurons and lymphocytes in mice persistently infected with lymphocytic choriomeningitis virus. Virology. 1993 Nov;197(1):463-7.
13. de la Torre JC, Rall G, Oldstone C, Sanna PP, Borrow P, Oldstone MB. Replication of lymphocytic choriomeningitis virus is restricted in terminally differentiated neurons. J Virol. 1993 Dec;67(12):7350-9.
14. Evans CF, Borrow P, de la Torre JC, Oldstone MB. Virus-induced immunosuppression: kinetic analysis of the selection of a mutation associated with viral persistence. J Virol. 1994 Nov;68(11):7367-73.
15. Gold LH, Brot MD, Polis I, Schroeder R, Tishon A, de la Torre JC, Oldstone MB, Koob GF. Behavioral effects of persistent lymphocytic choriomeningitis virus infection in mice. Behav Neural Biol. 1994 Sep;62(2):100-9.
16. Cubitt B, de la Torre JC. Borna disease virus (BDV), anonsegmented RNA virus, replicates in the nuclei of infected cells where infectious BDV ribonucleoproteins are present. J Virol. 1994 Mar;68(3):1371-81.
17. Cubitt B, Oldstone C, de la Torre JC. Sequence and genome organization of Borna disease virus. J Virol. 1994 Mar;68(3):1382-96.
18. Compans, R.W., L.R. Melsen and J.C. de la Torre . Virus-like particles in MDCK cells persistently infected with Borna disease virus. Virus Research 33:261-268, 1994.
19. Cubitt, B., C. Oldstone, J. Valcarcel and J.C. de la Torre . RNA splicing contributes to the generation of mature mRNAs of Borna disease virus, a nonsegmented negative strand RNA virus. Virus Research 34:69-79, 1994.
20. de la Torre JC. Molecular biology of borna disease virus: prototype of a new group of animal viruses. J Virol. 1994 Dec;68(12):7669-75. Review. No abstract available.
21. Buesa-Gomez J, de la Torre JC, Dyrberg T, Landin-Olsson M, Mauseth RS, Lernmark A, Oldstone MB. Failure to detect genomic viral sequences in pancreatic tissues from two children with acute-onset diabetes mellitus. J Med Virol. 1994 Feb;42(2):193-7.
22. Eddleston M, de La Torre JC, Xu JY, Dorfman N, Notkins A, Zolla-Pazner S, Oldstone MB. Molecular mimicry accompanying HIV-1 infection: human monoclonal antibodies that bind to gp41 and to astrocytes. AIDS Res Hum Retroviruses. 1993 Oct;9(10):939-44.
23. Oldstone MB, De La Torre JC. Viral diseases of the next century. Trans Am Clin Climatol Assoc. 1993;105:62-8. Review. No abstract available.
24. de la Torre JC, Oldstone MB. Anatomy of viral persistence: mechanisms of persistence and associated disease. Adv Virus Res. 1996;46:311-43. Review. No abstract available.
25. de la Torre JC, Mallory M, Brot M, Gold L, Koob G, Oldstone MB, Masliah E. Viral persistence in neurons alters synaptic plasticity and cognitive functions without destruction of brain cells. Virology. 1996 Jun 15;220(2):508-15.
26. Gonzalez-Dunia D, Eddleston M, Mackman N, Carbone K, de la Torre JC. Expression of tissue factor is increased in astrocytes within the central nervous system during persistent infection with borna disease virus. J Virol. 1996 Sep;70(9):5812-20.
27. de la Torre JC, Bode L, Durrwald R, Cubitt B, Ludwig H. Sequence characterization of human Borna disease virus. Virus Res. 1996 Sep;44(1):33-44.
28. De La Torre JC, Gonzalez-Dunia D, Cubitt B, Mallory M, Mueller-Lantzsch N, Grasser FA, Hansen LA, Masliah E. Detection of borna disease virus antigen and RNA in human autopsy brain samples from neuropsychiatric patients. Virology. 1996 Sep 15;223(2):272-82.
29. Sauder, C., A. Müller, B. Cubitt, J. Mayer, J. Steinmetz, W. Trabert, B. Ziegler, K. Wanke, N. Muller-Lantzsch, F.A. Grässer, and J.C. de la Torre. Detection of Borna disease virus (BDV) antibodies and BDV RNA in psychiatric patients: evidence for high sequence conservation of human blood derived BDV RNA. J. Virol. 70:7713-7724, 1996.
30. Gonzalez-Dunia D, Cubitt B, Grasser FA, de la Torre JC. Characterization of Borna disease virus p56 protein, a surface glycoprotein involved in virus entry. J Virol. 1997 Apr;71(4):3208-18.
31. Cao W, Oldstone MB, De La Torre JC. Viral persistent infection affects both transcriptional and posttranscriptional regulation of neuron-specific molecule GAP43. Virology. 1997 Apr 14;230(2):147-54.
32. Gonzalez-Dunia D, Sauder C, de la Torre JC. Borna disease virus and the brain. Brain Res Bull. 1997;44(6):647-64.
33. Cubitt B, de la Torre JC. Amantadine does not have antiviral activity against Borna disease virus. Arch Virol. 1997;142(10):2035-42.
34. Gonzalez-Dunia D, Cubitt B, de la Torre JC. Mechanism of Borna disease virus entry into cells. J Virol. 1998 Jan;72(1):783-8.
35. Sauder C, de la Torre JC. Sensitivity and reproducibility of RT-PCR to detect Borna disease virus (BDV) RNA in blood: implications for BDV epidemiology. J Virol Methods. 1998 Apr;71(2):229-45.
36. Sauder C, de la Torre JC. Cytokine expression in the rat central nervous system following perinatal Borna disease virus infection. J Neuroimmunol. 1999 Apr 1;96(1):29-45.
37. Hausmann, J., W. Hallensleben, J.C. de la Torre, A. Pagenstecher, C. Zimmermann, H. Pircher, and P. Staeheli. T cell ignorance in mice to Borna disease virus can be overcome by peripheral expression of the viral nucleoprotein. Proc. Natl. Acad. Sci. USA, 96:9769-9774, 1999.
38. Buesa-Gomez J, Teng MN, Oldstone CE, Oldstone MB, de la Torre JC. Variants able to cause growth hormone deficiency syndrome are present within the disease-nil WE strain of lymphocytic choriomeningitis virus. J Virol. 1996 Dec;70(12):8988-92.
39. Teng MN, Borrow P, Oldstone MB, de la Torre JC. A single amino acid change in the glycoprotein of lymphocytic choriomeningitis virus is associated with the ability to cause growth hormone deficiency syndrome. J Virol. 1996 Dec;70(12):8438-43.
40. Teng MN, Oldstone MB, de la Torre JC. Suppression of lymphocytic choriomeningitis virus--induced growth hormone deficiency syndrome by disease-negative virus variants. Virology. 1996 Sep 1;223(1):113-9.
41. Eddleston M, de la Torre JC, Campbell IL, Oldstone MB. The M22 antibody identifies highly activated reactive astrocytes responding to central nervous system disease. Acta Neuropathol (Berl). 1996;91(3):298-308.
42. Gonzalez-Dunia D, Watanabe M, Syan S, Mallory M, Masliah E, De La Torre JC. Synaptic pathology in Borna disease virus persistent infection. J Virol. 2000 Apr;74(8):3441-8.
43. Lee KJ, Novella IS, Teng MN, Oldstone MB, de La Torre JC. NP and L proteins of lymphocytic choriomeningitis virus (LCMV) are sufficient for efficient transcription and replication of LCMV genomic RNA analogs. J Virol. 2000 Apr;74(8):3470-7.
44. Sevilla N, Kunz S, Holz A, Lewicki H, Homann D, Yamada H, Campbell KP, de La Torre JC, Oldstone MB. Immunosuppression and resultant viral persistence by specific viral targeting of dendritic cells. J Exp Med. 2000 Nov 6;192(9):1249-60.
45. Lee KJ, Novella IS, Teng MN, Oldstone MB, de La Torre JC. NP and L proteins of lymphocytic choriomeningitis virus (LCMV) are sufficient for efficient transcription and replication of LCMV genomic RNA analogs. J Virol. 2000 Apr;74(8):3470-7.
46. Nakamura, Y., H. Takahashi, Y. Shoya, T. Nakaya, M. Watanabe, K. Tomonaga, K. Iwahashi, K. Ameno, N. Momiyama, H. Taniyama, T. Sata, T. Kurata, J.C. de la Torre* , and K. Ikuta. Isolation of Borna disease virus from human brain. J. Virol, 74:4601-4611, 2000.
47. Zocher, M., S. Czub, J. Schulte-Mönting, J.C. de la Torre* , and C. Sauder. J. Alterations in neurotrophin and neurotrophin receptor gene expression patterns in the rat central nervous system following perinatal Borna disease virus infection. Neurovirology, 6: 462-477, 2000.
48. Billaud, J.-N., C. Ly, T.R. Phillips and J.C. de la Torre. Borna disease virus persistence causes inhibition of glutamate uptake by feline primary cortical astrocytes. J.Virol, 74: 10438-10446, 2000.
49. Cubitt B, Ly C, de la Torre JC. Identification and characterization of a new intron in Borna disease virus. J Gen Virol. 2001 Mar;82(Pt 3):641-6.
50. de la Torre, J.C. Bornaviridae. In Fields Virology, Fourth Edition, D. Knipe and P. Howley, eds., Lippincott, Williams and Wilins. 2001.
51. Cornu TI, de la Torre JC. RING finger Z protein of lymphocytic choriomeningitis virus (LCMV) inhibits transcription and RNA replication of an LCMV S-segment minigenome. J Virol. 2001 Oct;75(19):9415-26.
52. Perez M, Watanabe M, Whitt MA, de la Torre JC. N-terminal domain of Borna disease virus G (p56) protein is sufficient for virus receptor recognition and cell entry. J Virol. 2001 Aug;75(15):7078-85.
53. de la Torre JC. Molecular biology of Borna disease virus and persistence. Front Biosci. 2002 Feb 1;7:d569-79. Review.
54. Lee KJ, de la Torre JC. Reverse genetics of arenaviruses. Curr Top Microbiol Immunol. 2002;262:175-93. Review. No abstract available.
55. Sevilla N, Domingo E, de la Torre JC. Contribution of LCMV towards deciphering biology of quasispecies in vivo. Curr Top Microbiol Immunol. 2002;263:197-220. Review.
56. Cornu TI, de la Torre JC. Characterization of the arenavirus RING finger Z protein regions required for Z-mediated inhibition of viral RNA synthesis. J Virol. 2002 Jul;76(13):6678-88.
57. Lee KJ, Perez M, Pinschewer DD, de la Torre JC. Identification of the lymphocytic choriomeningitis virus (LCMV) proteins required to rescue LCMV RNA analogs into LCMV-like particles. J Virol. 2002 Jun;76(12):6393-7.
58. Bajramovic J, Syan S, Brahic M, de la Torre, JC, Gonzalez-Dunia D. 1-b-D-arabinofuranosylcytosine (Ara-C) inhibits Borna disease virus replication and spread. J Virol. 76: 6268-6276, 2002.
59. de la Torre JC. Bornavirus and the brain. J Infect Dis. 2002 Dec 1;186 Suppl 2:S241-7. Review.
60. Pinschewer DD, Perez M, de la Torre JC. Role of the virus nucleoprotein in the regulation of lymphocytic choriomeningitis virus transcription and RNA replication. J Virol. 2003 Mar;77(6):3882-7.
61. Perez M, de la Torre JC. Characterization of the genomic promoter of the prototypic arenavirus lymphocytic choriomeningitis virus. J Virol. 2003 Jan;77(2):1184-94.
62. Ruiz-Jarabo CM, Ly C, Domingo E, de la Torre JC. Lethal mutagenesis of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV). Virology. 2003 Mar 30;308(1):37-47.
63. Perez M, Sanchez A, Cubitt B, Rosario D, de la Torre JC. A reverse genetics system for Borna disease virus. J Gen Virol. 2003 Nov;84(Pt 11):3099-104.
64. Perez M, Craven RC, de la Torre JC. The small RING finger protein Z drives arenavirus budding: implications for antiviral strategies. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12978-83. Epub 2003 Oct 16.
65. Pinschewer DD, Perez M, Sanchez AB, de la Torre JC. Recombinant lymphocytic choriomeningitis virus expressing vesicular stomatitis virus glycoprotein. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7895-900. Epub 2003 Jun 13.
66. Kunz S, Edelmann KH, de la Torre JC, Gorney R, Oldstone MB. Mechanisms for lymphocytic choriomeningitis virus glycoprotein cleavage, transport, and incorporation into virions. Virology. 2003 Sep 15;314(1):168-78.
67. Cornu TI, Feldmann H, de la Torre JC. Cells expressing the RING finger Z protein are resistant to arenavirus infection. J Virol. 2004 Mar;78(6):2979-83.
68. de la Torre JC. Bioterrorism and emerging infectious disease - antimicrobials, therapeutics and immune-modulators. Viral infections. IDrugs. 2004 Feb;7(2):96-9.
69. Ritchie KJ, Hahn CS, Kim KI, Yan M, Rosario D, Li L, de la Torre JC, Zhang DE. Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection. Nat Med. 2004 Dec;10(12):1374-8.
70. Pinschewer DD, Perez M, Jeetendra E, Bachi T, Horvath E, Hengartner H, Whitt MA, de la Torre JC, Zinkernagel RM. Kinetics of protective antibodies are determined by the viral surface antigen. J Clin Invest. 2004 Oct;114(7):988-93.
71. Perez M, Greenwald DL, de la Torre JC. Myristoylation of the RING finger Z protein is essential for arenavirus budding. J Virol. 2004 Oct;78(20):11443-8.
72. Pinschewer DD, Perez M, de la Torre JC. Dual role of the lymphocytic choriomeningitis virus intergenic region in transcription termination and virus propagation. J Virol. 2005 Apr;79(7):4519-26.
73. de la Torre JC. Arenavirus extinction through lethal mutagenesis. Virus Res. 2005 Feb;107(2):207-14.
74. Rosario D, Perez M, de la Torre JC. Functional characterization of the genomic promoter of borna disease virus (BDV): implications of 3'-terminal sequence heterogeneity for BDV persistence. J Virol. 2005 May;79(10):6544-50.
75. Kunz S, de la Torre JC. Novel antiviral strategies to combat human Arenavirus infections. Curr Mol Med. 2005 Dec;5(8):735-51.
76. Sánchez AB, Perez M, Cornu T, de la Torre JC. RNA interference-mediated virus clearance from cells both acutely and chronically infected with the prototypic arenavirus lymphocytic choriomeningitis virus. J Virol. 2005 Sep;79(17):11071-81.
77. Perez M, de la Torre JC. Identification of the Borna disease virus (BDV) proteins required for the formation of BDV-like particles. J Gen Virol. 2005 Jul;86(Pt 7):1891-5.
78. Sánchez AB, de la Torre JC. Genetic and biochemical evidence for an oligomeric structure of the functional L polymerase of the prototypic arenavirus lymphocytic choriomeningitis virus. J Virol. 2005 Jun;79(11):7262-8.
79. de la Torre JC. Reverse-genetic approaches to the study of Borna disease virus. Nat Rev Microbiol. 2006 Oct;4(10):777-83.
80. Martínez-Sobrido L, Zúñiga EI, Rosario D, García-Sastre A, de la Torre JC. Inhibition of the type I interferon response by the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus. J Virol. 2006 Sep;80(18):9192-9.
81. Kunz S, Rojek JM, Roberts AJ, McGavern DB, Oldstone MB, de la Torre JC. Altered central nervous system gene expression caused by congenitally acquired persistent infection with lymphocytic choriomeningitis virus. J Virol. 2006 Sep;80(18):9082-92.
82. Bergthaler A, Gerber NU, Merkler D, Horvath E, de la Torre JC, Pinschewer DD. Envelope exchange for the generation of live-attenuated arenavirus vaccines. PLoS Pathog. 2006 Jun;2(6):e51.
83. Sevilla N, de la Torre JC. Arenavirus diversity and evolution: quasispecies in vivo. Curr Top Microbiol Immunol. 2006;299:315-35.
84. Flatz L, Bergthaler A, de la Torre JC, Pinschewer DD. Recovery of an arenavirus entirely from RNA polymerase I/II-driven cDNA. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4663-8.
85. Sánchez AB, de la Torre JC. Rescue of the prototypic Arenavirus LCMV entirely from plasmid. Virology. 2006 Jul 5;350(2):370-80.
86. Yanai H, Kobayashi T, Hayashi Y, Watanabe Y, Ohtaki N, Zhang G, de la Torre JC, Ikuta K, Tomonaga K. A methionine-rich domain mediates CRM1-dependent nuclear export activity of Borna disease virus phosphoprotein. J Virol. 2006 Feb;80(3):1121-9.
87. Kim KI, Yan M, Malakhova O, Luo JK, Shen MF, Zou W, de la Torre JC, Zhang DE. Ube1L and protein ISGylation are not essential for alpha/beta interferon signaling. Mol Cell Biol. 2006 Jan;26(2):472-9.
88. Hagiwara K, Tsuge Y, Asakawa M, Kabaya H, Okamoto M, Miyasho T, Taniyama H, Ishihara C, de la Torre JC, Ikuta K. Borna disease virus RNA detected in Japanese macaques (Macaca fuscata). Primates. 2008 Jan;49(1):57-64.
89. Martínez-Sobrido L, Giannakas P, Cubitt B, García-Sastre A, de la Torre JC. Differential inhibition of type I interferon induction by arenavirus nucleoproteins. J Virol. 2007 Nov;81(22):12696-703.
90. Capul AA, Perez M, Burke E, Kunz S, Buchmeier MJ, de la Torre JC. Arenavirus Z-glycoprotein association requires Z myristoylation but not functional RING or late domains. J Virol. 2007 Sep;81(17):9451-60.
91. Saunders AA, Ting JP, Meisner J, Neuman BW, Perez M, de la Torre JC, Buchmeier MJ. Mapping the landscape of the lymphocytic choriomeningitis virus stable signal peptide reveals novel functional domains. J Virol. 2007 Jun;81(11):5649-57.
92. Perez M, Clemente R, Robison CS, Jeetendra E, Jayakar HR, Whitt MA, de la Torre JC. Generation and characterization of a recombinant vesicular stomatitis virus expressing the glycoprotein of Borna disease virus. J Virol. 2007 Jun;81(11):5527-36.
93. Clemente R, de la Torre JC. Cell-to-cell spread of Borna disease virus proceeds in the absence of the virus primary receptor and furin-mediated processing of the virus surface glycoprotein. J Virol. 2007 Jun;81(11):5968-77.
94. Capul AA, de la Torre JC. A cell-based luciferase assay amenable to high-throughput screening of inhibitors of arenavirus budding. Virology. 2008 Dec 5;382(1):107-14.
95. de la Torre JC. Reverse genetics approaches to combat pathogenic arenaviruses. Antiviral Res. 2008 Dec;80(3):239-50.
96. Rojek JM, Sanchez AB, Nguyen NT, de la Torre JC, Kunz S. Different mechanisms of cell entry by human-pathogenic Old World and New World arenaviruses. J Virol. 2008 Aug;82(15):7677-87.
97. Chen M, Lan S, Ou R, Price GE, Jiang H, de la Torre JC, Moskophidis D. Genomic and biological characterization of aggressive and docile strains of lymphocytic choriomeningitis virus rescued from a plasmid-based reverse-genetics system. J Gen Virol. 2008 Jun;89(Pt 6):1421-33.
98. Lad SP, Yang G, Scott DA, Chao TH, Correia Jda S, de la Torre JC, Li E. Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling. Mol Immunol. 2008 Apr;45(8):2277-87.
99. Hagiwara K, Tsuge Y, Asakawa M, Kabaya H, Okamoto M, Miyasho T, Taniyama H, Ishihara C, de la Torre JC, Ikuta K. Borna disease virus RNA detected in Japanese macaques (Macaca fuscata). Primates. 2008 Jan;49(1):57-64.
100. Urata S, Yasuda J, de la Torre JC. The z protein of the new world arenavirus tacaribe virus has bona fide budding activity that does not depend on known late domain motifs. J Virol. 2009 Dec;83(23):12651-5.
101. de la Torre JC. Molecular and cell biology of the prototypic arenavirus LCMV: implications for understanding and combating hemorrhagic fever arenaviruses. Ann N Y Acad Sci. 2009 Sep;1171 Suppl 1:E57-64.
102. Martínez-Sobrido L, Emonet S, Giannakas P, Cubitt B, García-Sastre A, de la Torre JC. Identification of amino acid residues critical for the anti-interferon activity of the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus. J Virol. 2009 Nov;83(21):11330-40.
103. Clemente R, de la Torre JC. Cell entry of Borna disease virus follows a clathrin-mediated endocytosis pathway that requires Rab5 and microtubules. J Virol. 2009 Oct;83(20):10406-16.
104. Emonet SF, de la Torre JC, Domingo E, Sevilla N. Arenavirus genetic diversity and its biological implications. Infect Genet Evol. 2009 Jul;9(4):417-29.
105. Emonet SF, Garidou L, McGavern DB, de la Torre JC. Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest. Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):3473-8.
106. Clemente R, de Parseval A, Perez M, de la Torre JC. Borna disease virus requires cholesterol in both cellular membrane and viral envelope for efficient cell entry. J Virol. 2009 Mar;83(6):2655-62.
107. Borrow P, Martínez-Sobrido L, de la Torre JC. Inhibition of the type I interferon antiviral response during arenavirus infection. Viruses. 2010 Nov;2(11):2443-80.
108. Ward SV, George CX, Welch MJ, Liou LY, Hahm B, Lewicki H, de la Torre JC, Samuel CE, Oldstone MB. RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):331-6.
109. Emonet SF, Seregin AV, Yun NE, Poussard AL, Walker AG, de la Torre JC, Paessler S. Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic Romero and live-attenuated Candid #1 strains of Junin virus, the causative agent of Argentine hemorrhagic fever disease. J Virol. 2011 Feb;85(4):1473-83.
110. Rodrigo WW, de la Torre JC, Martínez-Sobrido L. Use of single-cycle infectious lymphocytic choriomeningitis virus to study hemorrhagic fever arenaviruses. J Virol. 2011 Feb;85(4):1684-95.
111. Mendenhall M, Russell A, Juelich T, Messina EL, Smee DF, Freiberg AN, Holbrook MR, Furuta Y, de la Torre JC, Nunberg JH, Gowen BB. T-705 (favipiravir) inhibition of arenavirus replication in cell culture. Antimicrob Agents Chemother. 2011 Feb;55(2):782-7.
112. Pasqual G, Burri DJ, Pasquato A, de la Torre JC, Kunz S. Role of the host cell's unfolded protein response in arenavirus infection. J Virol. 2011 Feb;85(4):1662-70.
113. Urata S, Yun N, Pasquato A, Paessler S, Kunz S, de la Torre JC. Antiviral activity of a small-molecule inhibitor of arenavirus glycoprotein processing by the cellular site 1 protease. J Virol. 2011 Jan;85(2):795-803.
114. Volpon L, Osborne MJ, Capul AA, de la Torre JC, Borden KL. Structural characterization of the Z RING-eIF4E complex reveals a distinct mode of control for eIF4E. Proc Natl Acad Sci U S A. 2010 Mar 23;107(12):5441-6.
115. Clemente R, Sisman E, Aza-Blanc P, de la Torre JC. Identification of host factors involved in borna disease virus cell entry through a small interfering RNA functional genetic screen. J Virol. 2010 Apr;84(7):3562-75.
116. Rojek JM, Pasqual G, Sanchez AB, Nguyen NT, de la Torre JC, Kunz S. Targeting the proteolytic processing of the viral glycoprotein precursor is a promising novel antiviral strategy against arenaviruses. J Virol. 2010 Jan;84(1):573-84.
117. Urata S, de la Torre JC. Arenavirus budding. Adv Virol. 2011;2011:180326.
118. Pasquato A, Rochat C, Burri DJ, Pasqual G, de la Torre JC, Kunz S. Evaluation of the anti-arenaviral activity of the subtilisin kexin isozyme-1/site-1 protease inhibitor PF-429242. Virology. 2012 Feb 5;423(1):14-22.
119. Hastie KM, Liu T, Li S, King LB, Ngo N, Zandonatti MA, Woods VL Jr, de la Torre JC, Saphire EO. Crystal structure of the Lassa virus nucleoprotein-RNA complex reveals a gating mechanism for RNA binding. Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19365-70.
120. Ortiz-Riaño E, Cheng BY, de la Torre JC, Martínez-Sobrido L. The C-terminal region of lymphocytic choriomeningitis virus nucleoprotein contains distinct and segregable functional domains involved in NP-Z interaction and counteraction of the type I interferon response. J Virol. 2011 Dec;85(24):13038-48.
121. Mulherkar N, Raaben M, de la Torre JC, Whelan SP, Chandran K. The Ebola virus glycoprotein mediates entry via a non-classical dynamin-dependent macropinocytic pathway. Virology. 2011 Oct 25;419(2):72-83.
122. Popkin DL, Teijaro JR, Lee AM, Lewicki H, Emonet S, de la Torre JC, Oldstone M. Expanded potential for recombinant trisegmented lymphocytic choriomeningitis viruses: protein production, antibody production, and in vivo assessment of biological function of genes of interest. J Virol. 2011 Aug;85(15):7928-32.
123. Moreno H, Gallego I, Sevilla N, de la Torre JC, Domingo E, Martín V. Ribavirin can be mutagenic for arenaviruses. J Virol. 2011 Jul;85(14):7246-55.
124. Popkin DL, Teijaro JR, Sullivan BM, Urata S, Rutschmann S, de la Torre JC, Kunz S, Beutler B, Oldstone M. Hypomorphic mutation in the site-1 protease Mbtps1 endows resistance to persistent viral infection in a cell-specific manner. Cell Host Microbe. 2011 Mar 17;9(3):212-22.
125. Emonet SE, Urata S, de la Torre JC. Arenavirus reverse genetics: new approaches for the investigation of arenavirus biology and development of antiviral strategies. Virology. 2011 Mar 15;411(2):416-25.
126. Sullivan BM, Emonet SF, Welch MJ, Lee AM, Campbell KP, de la Torre JC, Oldstone MB. Point mutation in the glycoprotein of lymphocytic choriomeningitis virus is necessary for receptor binding, dendritic cell infection, and long-term persistence. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2969-74.
127. Nicolaou KC, Sanchini S, Sarlah D, Lu G, Wu TR, Nomura DK, Cravatt BF, Cubitt B, de la Torre JC, Hessell AJ, Burton DR. Design, synthesis, and biological evaluation of a biyouyanagin compound library. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6715-20.
128. Capul AA, de la Torre JC, Buchmeier MJ. Conserved residues in Lassa fever virus Z protein modulate viral infectivity at the level of the ribonucleoprotein. J Virol. 2011 Apr;85(7):3172-8.
129. Ward SV, George CX, Welch MJ, Liou LY, Hahm B, Lewicki H, de la Torre JC, Samuel CE, Oldstone MB. RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):331-6.
130. Emonet SF, Seregin AV, Yun NE, Poussard AL, Walker AG, de la Torre JC, Paessler S. Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic Romero and live-attenuated Candid #1 strains of Junin virus, the causative agent of Argentine hemorrhagic fever disease. J Virol. 2011 Feb;85(4):1473-83.
131. Rodrigo WW, de la Torre JC, Martínez-Sobrido L. Use of single-cycle infectious lymphocytic choriomeningitis virus to study hemorrhagic fever arenaviruses. J Virol. 2011 Feb;85(4):1684-95.
132. Mendenhall M, Russell A, Juelich T, Messina EL, Smee DF, Freiberg AN, Holbrook MR, Furuta Y, de la Torre JC, Nunberg JH, Gowen BB. T-705 (favipiravir) inhibition of arenavirus replication in cell culture. Antimicrob Agents Chemother. 2011 Feb;55(2):782-7.
133. Pasqual G, Burri DJ, Pasquato A, de la Torre JC, Kunz S. Role of the host cell's unfolded protein response in arenavirus infection. J Virol. 2011 Feb;85(4):1662-70.
134. Urata S, Yun N, Pasquato A, Paessler S, Kunz S, de la Torre JC. Antiviral activity of a small-molecule inhibitor of arenavirus glycoprotein processing by the cellular site 1 protease. J Virol. 2011 Jan;85(2):795-803.
135. Ortiz-Riaño E, Cheng BY, de la Torre JC, Martínez-Sobrido L. D471G mutation in LCMV-NP affects its ability to self-associate and results in a dominant negative effect in viral RNA synthesis. Viruses. 2012 Oct 16;4(10):2137-61.
136. Sung JH, Zhang H, Moseman EA, Alvarez D, Iannacone M, Henrickson SE, de la Torre JC, Groom JR, Luster AD, von Andrian UH. Chemokine guidance of central memory T cells is critical for antiviral recall responses in lymph nodes. Cell 2012 Sep 14;150(6):1249-63.
137. Huang C, Kolokoltsova OA, Yun NE, Seregin AV, Poussard AL, Walker AG, Brasier AR, Zhao Y, Tian B, de la Torre JC, Paessler S. Junín virus infection activates the type I interferon pathway in a RIG-I-dependent manner. PLoS Negl Trop Dis. 2012;6(5):e1659.
138. Rodrigo WW, Ortiz-Riaño E, Pythoud C, Kunz S, de la Torre JC, Martínez-Sobrido L. Arenavirus nucleoproteins prevent activation of nuclear factor kappa B. J Virol. 2012 Aug;86(15):8185-97.
139. Chen AT, Cornberg M, Gras S, Guillonneau C, Rossjohn J, Trees A, Emonet S, de la Torre JC, Welsh RM, Selin LK. Loss of anti-viral immunity by infection with a virus encoding a cross-reactive pathogenic epitope. PLoS Pathog. 2012;8(4):e1002633.
140. Pythoud C, Rodrigo WW, Pasqual G, Rothenberger S, Martínez-Sobrido L, de la Torre JC, Kunz S. Arenavirus nucleoprotein targets interferon regulatory factor-activating kinase IKKε. J Virol. 2012 Aug;86(15):7728-38.
141. Moreno H, Tejero H, de la Torre JC, Domingo E, Martín V. Mutagenesis-mediated virus extinction: virus-dependent effect of viral load on sensitivity to lethal defection. PLoS One 2012;7(3):e32550.
142. Urata S, Ngo N, de la Torre JC. The PI3K/Akt pathway contributes to arenavirus budding. J Virol. 2012 Apr;86(8):4578-85.
143. Ortiz-Riaño E, Cheng BY, de la Torre JC, Martínez-Sobrido L. Self-association of lymphocytic choriomeningitis virus nucleoprotein is mediated by its N-terminal region and is not required for its anti-interferon function. J Virol. 2012 Mar;86(6):3307-17.
144. Pasquato A, Rochat C, Burri DJ, Pasqual G, de la Torre JC, Kunz S. Evaluation of the anti-arenaviral activity of the subtilisin kexin isozyme-1/site-1 protease inhibitor PF-429242. Virology. 2012 Feb 5;423(1):14-22.
145. Cheng BY, Ortiz-Riaño E, de la Torre JC, Martínez-Sobrido L. Generation of Recombinant Arenavirus for Vaccine Development in FDA-Approved Vero Cells. J Vis Exp. 2013 Aug 1;(78).
146. Yun NE, Seregin AV, Walker DH, Popov VL, Walker AG, Smith JN, Miller M, de la Torre JC, Smith JK, Borisevich V, Fair JN, Wauquier N, Grant DS, Bockarie B, Bente D, Paessler S. Mice Lacking Functional STAT1 Are Highly Susceptible to Lethal Infection with Lassa Virus. J Virol. 2013 Oct;87(19):10908-11.
147. Vázquez-Calvo A, Martín-Acebes MA, Sáiz JC, Ngo N, Sobrino F, de la Torre JC. Inhibition of multiplication of the prototypic arenavirus LCMV by valproic acid. Antiviral Res. 2013 Aug;99(2):172-9.
148. Teijaro JR, Ng C, Lee AM, Sullivan BM, Sheehan KC, Welch M, Schreiber RD, de la Torre JC, Oldstone MB. Persistent LCMV infection is controlled by blockade of type I interferon signaling. Science. 2013 Apr 12;340(6129):207-11.
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