97.  Fang V, Chaluvadi VS, Ramos-Perez WD, Mendoza A, Baeyens A, Rivera R, Chun J, Cammer M, Schwab SR.  Gradients of the signaling lipid S1P in lymph nodes position natural killer cells and regulate their interferon-γ response. Nature Immunol epub ahead of print 2016 Nov 14. doi:10.1038/ni.3619.

96.  Gazit SL, Mariko B, Therond P, Decouture B, Xiong Y, Couty L, Bonnin P, Baudrie V, Le Gall SM, Dizier B, Zoghdani N, Ransinan J, Hamilton JR, Gaussem P, Tharaux PL, Chun J, Coughlin SR, Bachelot-Loza C, Hla T, Ho-Tin-Noe B, Camerer E.  Platelet and erythrocyte sources of S1P are redundant for vascular development and homeostasis, but both rendered essential after plasma S1P depletion in anaphylactic shock.  Circ Res 2016;119(8):e110-e126.

95.  Clay H, Wilsbacher LD, Wilson SJ, Duong DN, McDonald M, Lam I, Park KE, Chun J, Coughlin SR.  Sphingosine 1-phosphate receptor-1 in cardiomyocytes is required for normal cardiac development.  Dev Biol 2016;418(1):157-165.  PMC5031538

94.  Keul P, van Borren MM, GhanemA, Muller FU, Baartscheer A, Verkerk AO, Stumpel F, Schulte JS, Hamdani N, Linke WA, van Loenen P, Matus M, Schmitz W, Stypmann J, Tiemann K, Ravesloot JH, Alewijinse AE, Hermann S, Spijkers LJ, Herr D, Heusch G, Schafers M, Peters SL, Chun J, Levkau B.  Spingosine 1-phosphate receptor 1 regulates cardiac function by modulating Ca2+ sensitivity and Na+/H+ exchange and mediates protection by ischemic preconditioning.  J Am Heart Assoc 2016;5(5):pii: e003393.  PMC4889204

93.  Alfonzo-Mendez MA, Castillo-Badillo JA, Romero-Avila MT, Rivera R, Chun J, Garcia-Sainz JA.  Carboxyl terminus-truncated alpha1D-adrenoceptors inhibit the ERK pathway.  Naunyn Schmiedebergs Arch Pharmacol 2016;389(8):911-920.

92.  Funke M, Knudsen L, Lagares D, Ebener S, Probst CK, Fontaine BA, Franklin A, Kellner M, Kuhnel M, Matthieu S, Grothausmann, Chun J, Roberts JD Jr, Ochs M, Tager AM.  Lyosphosphatidic acid signaling through the lysophosphatidic acid-1 receptor is required for alveolarization.  Am J Respir Cell Mol Biol 2016;55(1):105-116.  PMC4942205

91.  Herr DR, Reolo MJ, Peh YX, Wang W, Lee CW, Rivera R, Paterson IC, Chun J.  Sphingosine 1-phosphate receptor 2 (S1P2) attenuates reactive oxygen species formation and inhibits cell death:  implications for otoprotective therapy.  Sci Rep 2016;6:24541.  PMC4832229

90.  Nishioka T, Arima N, Kano K, Hama K, Itai E, Yukiura H, Kise R, Inoue A, Kim SH, Solnica-Krezel L, Moolenaar WH, Chun J, Aoki J.  ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation.  Sci Rep 2016;6:23433. doi: 10.1038/srep23433.  PMC4804234

89.  Kitada Y, Kajita K, Taguchi K, Mori I, Yamauchi M, Ikeda T, Kawashima M, Asano M, Kajita T, Ishizuka T, Banno Y, Kojima I, Chun J, Kamata S, Ishii I, Morita H.  Blockade of sphingosine 1-phosphate receptor 2 signaling attenuates high-fat diet-induced adipocyte hypertrophy and systemic glucose intolerance in mice.  Endocrinology 2016;157(5):1839-1851.

88.  Fan J, Salathia N, Liu R, Kaeser GE, Yung YC, Herman JL, Kaper F, Fan JB, Zhang K, Chun J, Kharchenko PV.  Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis.  Nat Methods 2016;13(3):241-244.  

87.  Xu K, Ma L, Li Y, Wang F, Zheng G-Y, Sun Z, Jiang F, Chen Y, Liu H, Dang A, Chen X, Chun J, Tian X-L.  Genetic and functional evidence supports LPAR1 as a susceptibility gene for hypertension.  Hypertension 2015;doi:10.1161/hypertensionaha.115.05515  

86.  Keller J, Catala-Lehnen P, Huebner AK, Jeschke A, Heckt T, Lueth A, Krause M, Koehne T, Albers J, Schulze J, Schilling S, Haberland M, Denninger H, Neven M, Hermans-Borgmeyer I, Streichert T, Breer S, Barvencik F, Levkau B, Rathkolb B, Wolf E, Calzada-Wack J, Neff F, Gailus-Durner V, Fuchs H, de Angelis MH, Klutmann S, Tsourdi E, Hofbauer LC, Kleuser B, Chun J, Schinke T, Amling M.  Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts.  Nat Commun 2014;5:5215.  PMC4205484  DOWNLOAD PDF

85.  David M, Machuca-Gayet I, Kikuta J, Ottewell P, Mima F, Leblanc R, Bonnelye E, Ribeiro J, Holen I, Lopez Vales R, Jurdic P, Chun J, Clezardin P, Ishii M, Peyruchaud O.  Lysophosphatidic acid receptor type 1 (LPA1) plays a functional role in osteoclast differentiation an bone resorption activity.  J Bio Chem 2014;289(10):6551-6564.  PMC3945319  DOWNLOAD PDF

84.  Wu DD, Zhang F, Hao F, Chun J, Xu X, Cui MZ.  Matricellular protein Cyr61 bridges lysophosphatidic acid and integrin pathways leading to cell migration.  J Biol Chem 2014;289(9):5774-5783.  PMC3937649  DOWNLOAD PDF

83.  Herr DR, Lee CW, Wang W, Ware A, Rivera R, Chun J.  Sphingosine 1-phosphate receptors are essential mediators of eyelid closure during embryonic development.  J Biol Chem 2013;288(41):29882-29889.  PMC3795286  DOWNLOAD PDF

81.  Huang LS, Fu P, Patel P, Harijith A, Sun T, Zhao Y, Garcia JG, Chun J, Natarajan V.  Lysophosphatidic acid receptor 2 deficiency confers protection against bleomycin-induced lung injury and fibrosis in mice.  Am J Respir Cell Mol Biol 2013;49(6):912-22.  PMC3931116  DOWNLOAD PDF

80.  Miyabe Y, Miyabe C, Iwai Y, Takayasu A, Fukuda S, Yokoyama W, Nagai J, Jona M, Tokuhara Y, Ohkawa R, Albers HM, Ovaa H, Aoki J, Chun J, Yatomi Y, Ueda H, Miyasaka M, Miyasaka N, Nanki T.  Lysophosphatidic acid receptor 1 is essential for development of arthritis.  Arthritis Rheum 2013;65(8):2037-2047.  DOWNLOAD PDF

79.  Lee SJ, Leoni G, Neurmann PA, Chun J, Nusrat A, Yun CC.  Distinct phospholipase C-β isozymes mediate lysophosphatidic acid receptor 1 effects on intestinal epithelial homeostatis and wound closure.  Mol Cell Biol 2013;33(10):2016-2028.  PMC3647975  DOWNLOAD PDF

78.  Sakai N, Chun J, Duffield JS, Wada T, Luster AD, Tager AM.  LPA₁-induced cytoskeleton reorganization drives fibrosis through CTGF-dependent fibroblast proliferation.  FASEB J 2013;27(5):1830-1846.  PMC3633809  DOWNLOAD PDF

77.  Zhao Y, Fu P, Zhao J, Mialki RK, Wei J, Huang L, Chun J, Leme AS, Shapiro SD, Natarajan V.  Sepsis by using cecal ligation and single puncture causes alveolar space enlargement in LPA₂ knockout mice. J Aller Ther 2012;S4 005.  doi:  10.4172/2155-6121.S4-005.  DOWNLOAD PDF

76.  Lysophospholipid receptors:  signaling and biochemistry. Edited by Chun J, Hla T, Spiegel S, Moolenaar W.  John Wiley & Sons, Inc., Hoboken, NJ. 2013. 

75.  Ye X, Diao H, Chun J.  11-deoxy prostaglandin F(2a), a thromboxane A2 receptor agonist, partially alleviates embryo crowding in Lpar3((-/-)) females.  Fertil Steril 2012;97(3):757-763. PMC3315158    DOWNLOAD PDF

74.  Funke M, Xhao Z, Xu Y, Chun J, Tager AM.  The lysophosphatidic acid receptor LPA1 promotes epithelial cell apoptosis following lung injury.  Am J Respir Cell Mol Biol 2012;46(3):355-364. PMC3326436    DOWNLAOD PDF

73.  Cheng HY, Dong A, Panchatcharam M, Mueller P, Yang F, Li Z, Mills G, Chun J, Morris AJ, Smyth SS.  Lysophosphatidic acid signaling protects pulmonary vasculature from hypoxia induced remodeling.  Arterioscler Thromb Vasc Biol 2012;32(1):24-32. PMC3241874    DOWNLOAD PDF

72.  Mutoh T, Rivera R, Chun J.  Insights into the pharmacological relevance of lysophospholipid receptors.  Br J Pharmacol 2012;165(4):829-844. PMC3312481    DOWNLOAD PDF

71.  Zhao J, He D, Su Y, Berdyshev EV, Chun J, Natarajan V, Zhao Y.  Lysophosphatidic acid receptor 1 modulates lipopolysaccharide-induced inflammation in alveolar epithelial cells and murine lungs.  Am J Physiol Physiol Lung Cell Mol Physiol 2011;301(4):L547-L556. PMC3191756    DOWNLOAD PDF

70.  Peterson SE, Westra JW, Rehen SK, Young H, Bushman DM, Paczkowski CM, Yung YC, Lynch CL, Tran HT, Nickey KS, Wang YC, Laurent LC, Loring JF, Carpenter MK, Chun J.  Normal human pluripotent stem cell lines exhibit pervasive mosaic aneuploidy.  PLoS ONE 2011;6(8):e23018. PMC3156708    DOWNLOAD PDF

69.  Peterson SE, Chun J, Loring J.  FISH analysis of human pluripotent stem cells.  Methods Mol Biol 2011;767:191-200.    DOWNLOAD PDF

68.  Gennero I, Laurencin-Dalicieux S, Conte-Auriol F, Briand-Mesange F, Laurencin D, Rue J, Beton N, Malet N, Mus M, Tokumura A, Bourin P, Vico L, Brunel G, Oreffo RO, Chun J, Salles JP.  Absence of the lysophosphatidic acid receptor LPA1 results in abnormal bone development and decreased bone mass.  Bone 2011;49(3):395-403. PMC3697734    DOWNLOAD PDF

67.  Zhou Z, Subramanian P, Sevilmis G, Globke B, Soehnlein O, Karshovska E, Megens R, Heyll K, Chun J, Saulnier-Blache JS, Reinholz M, van Zandvoort M, Weber C, Schober A.  Lipoprotein-derived lysophosphatidic acid promotes atherosclerosis by releasing CXCL1 from the endothelium.  Cell Metab 2011;13(5):592-600.  DOWNLOAD PDF

66.  Ye X, Herr DR, Diao H, Rivera R, Chun J.  Unique uterine localization and regulation may differentiate LPA3 from other lysophospholipid receptors for its role in embryo implantation.  Fertil Steril 2011;95(6):2107-2113. PMC308461    DOWNLOAD PDF

65.  Park Hopson K, Truelove J, Chun J, Wang Y, Waeber C.  S1P activates store-operated calcium entry via receptor- and non-receptor-mediated pathways in vascular smooth muscle cells.  Am J Physiol Cell Physiol 2011;300(4):C919-C926. PMC3074633    DOWNLOAD PDF

64.  Castelino FV, Seiders J, Bain G, Brooks SF, King CD, Swaney JS, Lorrain DS, Chun J, Luster AD, Tager AM.  Amerlioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma.  Arthritis Rheum 2011;63(5):1405-1415.  PMC3086986    DOWNLOAD PDF

63.  Herzog C, Schmitz M, Levkau B, Herrgott I, Mersmann J, Larmann J, Kai J, Winterhalter M, Chun J, Ulrich Muller F, Echtermeyer F, Hildebrand R, Theilmeier G.  Intravenous sphingosylphosphorylcholine protects ischemic and post-ischemic myocardial tissue in a mouse model of myocardial ischemia/reperfusion injury.  Mediat Inflam 2011;425191. PMC3022218  DOWNLOAD PDF

62.  Diao H, Aplin JD, Xiao S, Chun J, Li Z, Chen S, Ye X.  Altered spatiotemporal expression of collagen types I, III, IV, and VI in Lpar3-deficient peri-implantation mouse uterus. Biol Reprod 2011;84(2):255-265. PMC3071265    DOWNLOAD PDF

61.  Shea BS, Brooks SF, Fontaine BA, Chun J, Luster AD, Tager AM.  Prolonged exposure to sphingosine 1-phosphate receptor 1 agonists exacerbates vascular leak, fibrosis, and mortality after lung injury.  Am J Respir Cell Mol Biol 2010;43(6):662-673.  PMC2993087    DOWNLOAD PDF

60.  Lin S, Lee SJ, Shim H, Chun J, Yun CC.  The absence of LPA receptor 2 reduces the tumorigenesis by ApcMin mutation in the intestine.  Am J Physiol Gastrointest Liver Physiol 2010;299(5):G1128-G1138. PMC2993170    DOWNLOAD PDF

59.  Diao H, Xiao S, Cui J, Chun J, Xu Y, Ye X.  Progesterone receptor-mediated up-regulation of transthyretin (TTR) in preimplantation mouse uterus.  Fertil Steril 2010;93(8):2750-2753.  PMC3646416    DOWNLOAD PDF

58.  Imasawa T, Koike K, Ishii I, Chun J, Yatomi Y.  Blockade of sphingosine 1-phosphate receptor 2 signaling attenuates streptozotocin-induced apoptosis of pancreatic beta-cells.  Biochem Biophys Res Comm 2010;392(2):207-211. PMC3649530   DOWNLOAD PDF

57.  Lin S, Yeruva S, He P, Singh AK, Zhang H, Chen M, Lamprecht G, de Jonge HR, Tse M, Donowitz M, Hogema BM, Chun J, Seidler U, Yun CC.  Lysophosphatidic acid stimulates the intestinal brush border Na⁺/H⁺ exchanger 3 and fluid absorption via LPA₅ and NHERF2.  Gastroenterology 2010;138(2):649-658. PMC2976485    DOWNLOAD PDF

56.  Takuwa N, Ohkura SI, Takashima SI, Ohtani K, Okamoto Y, Tanaka T, Hirano K, Usui S, Wang F, Du W, Yoshioka K, Banno Y, Sasaki M, Ichi I, Okamura M, Sugimoto N, Mizugishi K, Nakanuma Y, Ishii I, Takamura M, Kaneko S, Kojo S, Satouchi K, Mitumori K, Chun J, Takuwa Y.  S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species.  Cardiovasc Res 2010;85(3):484-493.  PMC2802201 

55.  Chun J, Hla T, Lynch KR, Spiegel S, Moolenaar WH.  International Union of Basic and Clinical Pharmacology. LXXVIII.  Lysophospholipid Receptor Nomenclature. Pharmacol Rev 2010;62(4):579-587. PMC2993255    DOWNLOAD PDF

54.  Choi JW, Herr DR, Noguchi K, Yung YC, Lee CW, Mutoh T, Lin M-E, Teo ST, Park KE, Mosley AN, Chun J.  LPA receptors:  Subtypes and biological actions.  Ann Rev Pharmacol Toxicol 2010;50:157–186.    DOWNLOAD PDF

53.  Ye X, Chun J.  Lysophosphatidic acid (LPA) signaling in vertebrate reproduction.  Trends Endocrin Metab 2010;21(1):17-24. PMC2818173    DOWNLOAD PDF

52.  Lin ME, Herr DR, Chun J.  Lysophosphatidic acid (LPA) receptors:  signaling properties and disease relevance. Prostaglandins Other Lipid Mediat 2010;91(3-4):130-138.  PMC2845529    DOWNLOAD PDF

51.  Zhao Y, Tong J, He D, Pendyala S, Evgeny B, Chun J, Sperling AI, Natarajan V.  Role of lysophosphatidic acid receptor LPA2 in the development of allergic airway inflammation in a murine model of asthma.  Respiratory Res 2009;10:114.  PMC2788521    DOWNLOAD PDF

50.  Nieuwenhuis B, Lüth A, Chun J, Huwiler A, Pfeilschifter J, Schäfer-Korting M, Kleuser B.  Involvement of the ABC-transporter ABCC1 and the sphingosine 1-phosphate receptor subtype S1P3 in the cytoprotection of human fibroblasts by the glucocorticoid dexamethasone.  J Mol Med 2009;87(6):645-657.    DOWNLOAD PDF

49.  Lin S, Wang D, Iver S, Ghaleb AM, Shim H, Yang VW, Chun J, Yun CC.  The absence of LPA(2) attenuates tumor formation in an experimental model of colitis-associated cancer.  Gastroenterology 2009;136(5):1711-20.  PMC2691721    DOWNLOAD PDF

48.  Ikeda H, Watanabe N, Ishii I, Shimosawa T, Kume Y, Yomiya T, Inoue Y, Nishikawa T, Ohtomo N, Tanoue Y, Iitsuka S, Fujita R, Omata M, Chun J, Yatomi Y.  Sphingosine 1-phosphate regulates regeneration and fibrosis after liver injury via sphingosine 1-phosphate receptor 2 (S1P2).  J Lipid Res 2009;50(3):556-564.  PMC2638109    DOWNLOAD PDF

47.  Yung YC, Kennedy G, Chun J.  Identification of neural programmed cell death through the detection of DNA fragmentation in situ and by PCR.  In Current Protocols in Neuroscience, Unit 3.8, Taylor G (Ed.), John Wiley & Sons, July 2009.  PMC2774705    DOWNLOAD PDF

46.  Teo ST, Yung YC, Herr DR, Chun J.  Lysophosphatidic acid in vascular development and disease.  IUBMB Life 2009;61(8):791-799.    DOWNLOAD PDF

45.  Mutoh T, Chun J.  Lysophosphatidic acid and sphingosine 1-phosphate activation of G Protein-Coupled Receptors.  In Bradshaw RA & Dennis EA (eds.) Handbook of Cell Signaling, second edition, Elsevier, 2009.

44.  Noguchi K, Herr D, Mutoh T, Chun J.  Lysophosphatidic acid (LPA) and its receptors.  Curr Opin Pharmacol 2009;9(1):15-23.    DOWNLOAD PDF

43.  Panchatcharam M, Miriyala S, Yang F, Rojas M, Vallant C, Dong A, Lynch K, Chun J, Morris AJ, Smyth SS.  Lysophosphatidic acid receptors 1 and 2 play roles in regulation of vascular injury responses but not blood pressure.  Circ Res 2008;103(6):662-670.  PMC2637300    DOWNLOAD PDF

42.  Tölle M, Pawlak A, Schuchardt M, Kawamura A, Tietge UJ, Lorkowski S, Keul P, Assmann G, Chun J, Levkau B, van der Giet M, Nofer JR.  HDL-associated lysosphingolipids inhibit NAD(P)H oxidase-dependent monocyte chemoattractant protein-1 production.  Arterioscler Thromb Vasc Biol 2008;28(8):1542-1548.  PMC2723752    DOWNLOAD PDF

41.  Ye X, Skinner MK, Kennedy G, Chun J.  Age-dependent loss of sperm production in mice via impaired lysophosphatidic acid signaling.  Biol Reprod 2008;79(2):328-336.  PMC2574971    DOWNLOAD PDF

40.  Choi JW, Lee CW, Chun J.  Biological roles of lysophospholipid receptors revealed by genetic null mice:  an update.  Biochem Biophys Acta 2008;1781:531-539.  PMC2657083    DOWNLOAD PDF

39.  Niessen F, Schaffner F, Furlan-Freguia C, Pawlinski R, Bhattacharjee G, Chun J, Derian CK, Andrade-Gordon P, Rosen H, Ruf W.  Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation.  Nature 2008;452(7187):654-658.    DOWNLOAD PDF

38.  Tager AM, LaCamera P, Shea BS, Campanella GK, Selman M, Zhao Z, Polosukhin Z, Wain J, Karimi-Shah BA, Kim ND, Hart WK, Pardo A, Blackwell TS, Xu Y, Chun J, Luster AD.  The lysophosphatidic acid receptor LPA₁ links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak.  Nat Med 2008;14(1):45-54.    DOWNLOAD PDF

37.  Mutoh T, Chun J.  Lysophospholipid activation of g protein-coupled receptors.  Subcell Biochem 2008;49:269-297.  

36.  Chun J.  “Extracellular Lipid Signals.” In the Wiley Encyclopedia of Chemical Biology, Tadhg P. Begley (ed.), 2008.

35.  Hama K, Aoki J, Inoue A, Endo T, Amano T, Motoki R, Kanai M, Ye X, Chun J, Matsuji N, Suzuki H, Shibasaski M, Arai H.  Embryo spacing and implantation timing are differentially regulated by LPA3-mediated lysophosphatidic acid signaling.  Biol Reprod 2007;77(6):954-9.    DOWNLOAD PDF

34.  Chun J.  How the lysophospholipid got its receptor.  The Scientist 2007;21(9):48-54.    Download PDF

33.  Chan LC, Peters W, Xu Y, Chun J, Farese Jr. RV, Cases S.  LPA₃ receptor mediates chemotaxis of immature murine dendritic cells to unsaturated lysophosphatidic acid (LPA).  J Leukocyte Biol 2007;82(5):1193-1200.    DOWNLOAD PDF

32.  Pradere J-P, Klein J, Gres S, Guigne C, Neau E, Valet P, Calise D, Chun J, Bascands J-L, Saulnier-Blache J-S, Schanstra JP. LPA₁ receptor activation promotes renal interstitial fibrosis.  J Am Soc Nephrology 2007;18(12):3110-3118.    DOWNLOAD PDF

31.  Serriere-Lanneau V, Teixeira-Clerc F, Li L, Schippers M, de Wries W, Julien B, Tran-Van-Nhieu J, Manin S, Poelstra K, Chun J, Carpentie S, Levade T, Mallat A, Lotersztajn S.  The sphingosine 1-phosphate receptor S1P₂ triggers hepatic wound healing.  FASEB J 2007;21(9):2005-2013.    DOWNLOAD PDF

30.  Means CK, Xiao CY, Li Z, Zhang T, Omens JH,  Ishii I, Chun J, Brown JH.  Sphingosine 1-phosphate S1P2 and S1P3 receptor-mediated Akt activation protects against in vivo myocardial ischemia-reperfusion injury.  Am J Physiol Heart Circ Physiol 2007;92(6):H2944-H2951.    DOWNLOAD PDF

29.  Rivera R, Chun J.  Potential therapeutic roles of lysophospholipid signaling in autoimmune related disease.  Future Lipidology 2007;2(5):535-545.

28.  Herr D, Chun J.  Effects of LPA and S1P on the nervous system and implications for their involvement in disease.  Cur Drug Targ 2007;8:155-167.    DOWNLOAD PDF

27.  Theilmeier G, Schmidt C, Herrmann J, Keul P, Schäfers M, Herrgott I, Mersmann J, Larmann J, Hermann S, Stypmann J, Schober O, Hildebrand R, Schulz R, Heusch G, Haude M, von Wnuck Lipinski K, Herzog C, Schmitz M, Erbel R, Chun J, Levkau, B.  High-density lipoproteins and their constituent sphingosine-1-phosphate directly protect the heart against ischemia/reperfusion injury in vivo via the S1P₃ lysophospholipid receptor.  Circulation 2006;114:1403-1409.    DOWNLOAD PDF

26.  Birgbauer E, Chun J.  New developments in the biological functions of lysophospholipids.  Cell Mol Life Sci 2006;63:2695-2701.    DOWNLOAD PDF

25.  Rivera R, Chun J.  Biological effects of lysophospholipids.  Rev Physiol Biochem Pharmacol 2008;160:25-46.    DOWNLOAD PDF

24.  Gardell SE, Dubin AE, Chun J.  Emerging medicinal roles for lysophospholipid receptors.  Trends in Mol Med 2006;12:65-75.   DOWNLOAD PDF

23.  Ye X, Hama K, Contos JJ, Anliker B, Inoue A, Skinner MK, Suzuki H, Amano T, Arai H, Aoki J, Chun J.  LPA₃-mediated lysophosphatidic acid signalling in embryo implantation and spacing.  Nature 2005;435:104-108.  (See also News & Views.)  PMC1369590    DOWNLOAD PDF

22.  Tölle M, Levkau B, Keul P, Brinkmann V, Giebing G, Schönfelder G, Schäfers M, von Wnuck Lipinski K, Jankowski J, Jankowski V, Chun J, Zidek W, van der Giet M.  The immunomodulator FTY720 induces eNOS-dependent arterial vasodilation via the lysophospholipid receptor S1P3.  Circ Res 2005;96:913-920.    DOWNLOAD PDF

21.  Li H, Ye X, Mahanivong C, Bian D, Chun J, Huang S.  Signaling mechanisms responsible for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells.  J Biol Chem 2005;280:10564-10571.    DOWNLOAD PDF

20.  Simon MF, Daviaud D, Pradere JP, Gres S, Guigne C, Wabitsch M, Chun J, Valet P, Saulnier-Blache JS.  Lysophosphatidic acid inhibits adipocyte differentiation via lysophosphatidic acid 1 receptor-dependent down-regulation of peroxisome proliferator-activated receptor gamma2.  J Biol Chem 2005;280:14656-14662.    DOWNLOAD PDF

19.  Girkontaite I, SakkV, Wagner M, Borggrefe T, Tedford K, Chun J, Fischer K-D.  The sphingosine-1-phosphate lysophospholipid receptor S1P₃ regulates MAdCAM-1+ endothelial cells in splenic marginal sinus organization.  J Exp Med 2004;200:1491-1501.  PMC2211946    DOWNLOAD PDF

18.  Levkau B, Hermann S, Theilmeier G, van der Giet M, Chun J, Schober O, Schäfers M.  HDL stimulates myocardial perfusion in vivo.  Circulation 2004;110:3355-3359.    DOWNLOAD PDF

17.  Hama K, Aoki J, Fukay M, Kishi Y, Ohta H, Sakai T, Suzuki R, Watanabe M, Chun J, Arai H. Lysophosphatidic acid and autotaxin stimulate cell motility of neoplastic and non-neoplastic cells through LPA₁.  J Biol Chem 2004;279:17634-17639.    DOWNLOAD PDF

16.  Sanna G, Alfonso A, Liao J, Ahn M-Y, Peterson MS, Jo E, Webb B, Lefebvre S, Chun J, Gray N, Rosen H. Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate.  J Biol Chem 2004;279:13839-13848.    DOWNLOAD PDF

15.  Nofer J-R, van der Giet M, Tölle M, Wolinska I, Sokoll A, von Wnuck-Lipinski K, Baba HA, Gödecke A, Ishii I, Kleuser B, Volker W, Fobker M, Zidek W, Assmann G, Chun J, Levkau B.  HDL induces NO-dependent vasorelaxation via the lysophospholipid receptor S1P₃:  role of HDL-associated lysophospholipids.  J Clin Invest 2004;113:569-581.  PMC338256    DOWNLOAD PDF

14.  Anliker B, Chun J. Lysophospholipid G protein-coupled receptors.  J Biol Chem 2004;279:20555-20558.    DOWNLOAD PDF

13.  Anliker B, Chun J.  Cell surface receptors in lysophospholipid signaling.  Sem Cell and Devel Biol 2004;15:457-465.    DOWNLOAD PDF

12.  Ishii I, Fukushima N, Ye X, Chun J.  Lysophospholipid receptors:  Signaling and biology.  Ann Rev Biochem 2004;73:321-354.   DOWNLOAD PDF

11.  Kingsbury MA, Rehen SK, Ye X, Chun J.  Genetics and cell biology of lysophosphatidic acid receptor-mediated signaling during cortical neurogenesis. J Cell Biochem 2004;92:1004-12.    DOWNLOAD PDF

10.  Rehen SK, McConnell MJ, Kaushal D, Kingsbury MA, Yang AH, Chun J.  Genetic mosaicism in the brain:  A new paradigm for neuronal diversity.  Dir in Science 2002;1:53-55.  

9.  Chun J, Goetzl EJ, Hla,TL, Igarashi Y, Lynch KR, Moolenaar WH, Pyne S, Tigyi G.  International Union of Pharmacology.  XXXIV.  Lysophospholipid receptor nomenclature.  Pharmacol Rev 2002;54:265-269.   DOWNLOAD PDF

8.  Pompeiano M, Hvala M, Chun J.  Onset of apoptotic DNA fragmentation can precede cell elimination by days in the small intestinal vilus.  Cell Death and Diff 1998;5:702-709.   DOWNLOAD PDF

7.  Fukushima N, Kimura Y, Chun J.  A single receptor encoded by vzg-1/lpa1/edg-2 couples to G-proteins and mediates multiple cellular responses to lysophosphatidic acid (LPA).  Proc Natl Acad Sci USA 1998;95:6151-6156.  PMC27607    DOWNLOAD PDF

6.  Bain G, Engel I, Maandag ECR, te Riele HPJ, Voland JR, Sharp LL, Chun J, Huey B, Pinkel D, Murre C.  E2A deficient mice rapidly develop T cell leukemias.  Mol Cell Biol 1997;17:4782-4791.  PMC232330    DOWNLOAD PDF

5.  Staley K, Blaschke AJ, Chun J.  Apoptotic DNA fragmentation is detected by a semi-quantitative ligation-mediated PCR of blunt DNA ends.  Cell Death and Differen 1997;4:66-75.    Download PDF

4.  Hecht JH, Weiner JA, Post SR, Chun J.  Ventricular zone gene -1 (Vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex.  J Cell Biol 1996;135:1071-1083.  PMC2133395    DOWNLOAD PDF

3.  Blaschke AJ, Staley K, Chun J.  Widespread programmed cell death in proliferative and postmitotic regions of the fetal cerebral cortex.  Development 1996;122:1165-1174 (see comment in Neuron 1996;16:693).    DOWNLOAD PDF

2.  Chun J, Contos JJA, Munroe D.  A growing family of receptor genes for lysophosphatidic acid (LPA) and other lysophospholipids (LPs).  Cell Biochem Biophys 1999;30:213-242.

1.  Turka LA, Schatz DG, Oettinger MA, Chun JJM, Gorka C, Lee K, McCormack WT, Thompson CB.  Thymocyte expression of the recombination activating genes RAG-1 and RAG-2 can be terminated by T-cell receptor stimulation in vitro.  Science 1991;253:778-781.

Return to top