Heart Disease

Heart disease encompasses a range of conditions that affect a person’s heart—from coronary artery disease and arrhythmias to heart defects and many others. Genomics can provide powerful tools to understand the underlying causes of these conditions and may be used for diagnosis and to guide treatment. Scientists at the Scripps Research Translational Institute are conducting a number of studies that leverage the remarkable progress being made in genomic technology to further our understanding of these conditions.

Studies

Unveiling the Role of the Most Impactful Cardiovascular Risk Locus through Haplotype Editing, Cell, December 2018

Validation of a genetic risk score for atrial fibrillation: A prospective multicenter cohort study, PLOS Medicine 2018

A Whole Blood Molecular Signature for Acute Myocardial Infarction, Sci Rep 2017

Fluid phase biopsy for detection and characterization of circulating endothelial cells in myocardial infarction, Physical Biology 2014

Characterization of circulating endothelial cells in acute myocardial infarction, Science Translational Medicine 2012

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