Grating Coupled Interferometry (GCI)
GCI is a well-established technique for observing and measuring the association and dissociation of molecular complexes. The Malvern Panalytical – Wave instrument is specifically manufactured for studying the interactions of large macromolecules with their small molecule counterparts. The Rapid Kinetics function allows for screening of hundreds of small molecules in a 24 hr period.
Results may include:
Results may include:
- Binding kinetic constants (ka, kd)
- Binding dissociation/association constants (Ka/Kd)
- Concentration determination
- Inhibitor Binding Concentrations (IC50)
- Interest in service, contact philo@scripps.edu
Malvern - Wave
Full-service only (internal pricing)$500 setup fee, $260/sample
