Contact: tongyao@scripps.edu
Education:
2009-2014 Ph.D., Biochemistry Hong Kong University of Science and Technology, Hong Kong
2005-2009 B.Sc., Biochemistry, Nanjing University, China
Current Research Focus:
I am currently focusing on studying novel functions of glycyl-tRNA synthetases (GlyRS) and its connections with Charcot-Marie-Tooth neurodegenerative disease.
Publications:
Y.J. Li, J.X. Song, Y. Tong, S.K. Chung, Y.H. Wong, RGS19 upregulates Nm23-H1/2 metastasis suppressors by transcriptional activation via the cAMP/PKA/CREB pathway, Oncotarget. 8 (2017) 69945-69960..
Y. Tong, L.Y. Yung, Y.H. Wong, Metastasis suppressors Nm23H1 and Nm23H2 differentially regulate neoplastic transformation and tumorigenesis. Cancer Letters. 361 (2015) 207-217.
Y.C. Wang, Y. Tong, P.H. Tso, Y.H. Wong, Regulator of G protein signaling 19 suppresses Ras-induced neoplastic transformation and tumorigenesis, Cancer Letters. 339 (2013) 33-41.
P.H. Tso, Y.C. Wang, L.Y. Yung, Y. Tong, M.M.K. Lee, Y.H. Wong, RGS19 inhibits Ras signaling through Nm23H1/2-mediated phosphorylation of the kinase suppressor of Ras, Cellular Signalling. 25 (2013) 1064-1074.
Y.J. Li, Y. Tong, Y.H. Wong, Regulatory functions of Nm23-H2 in tumorigenesis: insights from biochemical to clinical perspectives, Naunyn-Schmiedeberg's Archives of Pharmacology. 388 (2015) 243-256.