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Scripps Laboratories for tRNA Synthetase Research

Yao Tong, Ph.D.

Contact: tongyao@scripps.edu

Yao Tong

Education:
2009-2014  Ph.D., Biochemistry Hong Kong University of Science and Technology, Hong Kong
2005-2009  B.Sc., Biochemistry, Nanjing University, China                         

Current Research Focus:
I am currently focusing on studying novel functions of glycyl-tRNA synthetases (GlyRS) and its connections with Charcot-Marie-Tooth neurodegenerative disease.

Publications:
Y.J. Li, J.X. Song, Y. Tong, S.K. Chung, Y.H. Wong, RGS19 upregulates Nm23-H1/2 metastasis suppressors by transcriptional activation via the cAMP/PKA/CREB pathway, Oncotarget. 8 (2017) 69945-69960..

Y. Tong, L.Y. Yung, Y.H. Wong, Metastasis suppressors Nm23H1 and Nm23H2 differentially regulate neoplastic transformation and tumorigenesis. Cancer Letters. 361 (2015) 207-217.

Y.C. Wang, Y. Tong, P.H. Tso, Y.H. Wong, Regulator of G protein signaling 19 suppresses Ras-induced neoplastic transformation and tumorigenesis, Cancer Letters. 339 (2013) 33-41.

P.H. Tso, Y.C. Wang, L.Y. Yung, Y. Tong, M.M.K. Lee, Y.H. Wong, RGS19 inhibits Ras signaling through Nm23H1/2-mediated phosphorylation of the kinase suppressor of Ras, Cellular Signalling. 25 (2013) 1064-1074.

Y.J. Li, Y. Tong, Y.H. Wong, Regulatory functions of Nm23-H2 in tumorigenesis: insights from biochemical to clinical perspectives, Naunyn-Schmiedeberg's Archives of Pharmacology. 388 (2015) 243-256.

 

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