|
|
|
|
| Nahid Razi, Ph.D.
The Scripps Research Institute 10550 North Torrey Pines Road, CB-216 La Jolla, CA 92037 858-784-7539(phone) 858-784-7542 (fax) e-mail: nrazi@scripps.edu |
 |
|
ACADEMIC MERITS:
Ph. D. Medical Science, Uppsala University, Sweden, 1995 M. Sc. Biochemistry, University of Iowa, USA, 1984 EMPLOYMENTS: 2008- present Director for Carbohydrate Synthesis / Protein Expression Core, TSRI, San Diego, CA 2001-2008 Associate Director for Carbohydrate Synthesis / Protein Expression Core, TSRI, San Diego, CA 2000-2001 Researcher, Department of Surgery, UCSD, San Diego, CA 1998-2000 Research director, Paik-Inje Memorial Institute, San Diego, CA 1995-1998 Post doctoral, Immuno-glycobiology, Cancer Center, UCSD, San Diego, CA 1988-1989 Research scientist in Molecular Biology, Uppsala University 1984-1988 Lecturer of Biochemical Genetics, School of Medicine, Tehran University AWARDS AND SCHOLARSHIPS: 1998 Grant Award: "California Cancer Research Program", US 1997 Grant Award: "Cure for Lymphoma Foundation", US 1995 Grant Award: "Polysaccharide Research AB", Sweden 1990 Scholarship: "Uppsala University" 1978 First Rank Student Award: "Tehran University" PUBLICATIONS: Feinberg, H., Taylor, M., Razi, N., McBride, R., Knirel, Y., Graham, S., Drickamer, K., Weis, W. (2010) Structural Basis for Langerin Recognition of Diverse Pathogen and Mammalian Glycans through a Single Binding Site. J. Mol. Biol. In press Peng, W., Pranskevich, J., Nycholat, C., Gilbert, M., Wakarchuk, W., Paulson, J.C., Razi, N. (2010) Enzymatic Synthesis of Poly-N-Acetyllactosamine (Pln) Derivatives on Branched Glycans for the CFG Glycan Array. Glycobiology. 51: 1465 Niemietz, M., Razi, N., Paulson, J.C., and Unverzagt, C. (2010) Chemoenzymatic Synthesis of Tetraantennary Bisected Core Fucosylated N-glycan Derivatives for the CFG Glycan Array. International Carb. Symposium publication. A-P2-072 Razi, N., Mcbride, R., Peng, W., Pranskevich, J., Rangarajan, J., Paulson, J.C. (2010) Characteristics of the CFG Printed Glycan Microarray V5.0- Final Glue-Grant Funded. Glycobiology. 68: 1470 Blixt, O. and Razi, N. (2008) Enzymatic Synthesis with Transferases Glycoscience, (Ed. B. Fraser-Reid) in Glycoscience, Chemistry and Chemical Biology, Springer-Verlag Berlin Heidelberg New York. Blixt, O., Allin, K., Bohorov, O., Liu, X., Andersson-Sand, H., Hoffman, J. and Razi, N. (2008) Glycan microarrays for screening sialyltransferase specificities. Glycoconj. J. 25(1), 59-68. Vasiliu, D., Razi, N., Zhang, Y., Jacobsen, N., Allin, K., Liu, X., Hoffmann, J., Bohorov, O. and Blixt, O. (2006) Large scale chemoenzymatic synthesis of blood group and tumor-associated poly-N-acetyllactosamine antigens. Carbohydr Res 341, 1447-1457. Blixt, O. and Razi, N. (2006) Chemoenzymatic synthesis of glycan libraries. Methods Enzymol. 415, 137-53. Blixt, O., Vasiliu, D., Allin, K., Jacobsen, N., Warnock, D., Razi, N., Paulson, J. Benatchez, S., Gilbert, M., and Wakarchuck, W. (2005) Chemoenzymatic synthesis of 2-azidoethyl-ganglio-oligosaccharides GD3, GT3, GM2, GD2, GT2, GM1, and GD1a, Carbohydrtae research, 340, 1963-1972 Westerklind, U., Hagback, P., Tidback, B., Wiik, L., Blixt, O., Razi, N., and Norberg, T. (2005) Synthesis of deoxy and acylamino derivatives of lactose and use of these for probing the active site of Neisseria meningitides N-acetylglucosaminyltransferase. Carbohydrate Research 340, 221-233. Blixt, O., and Razi, N. (2004) Stategies for synthesis of an oligosaccharide library using a chemo-enzymatic approach. In synthesis of carbohydrate through biotechnology. ACS Symposium series 873. P.G. Wang and Y. Ichikawa 93-112 Blixt, O. Head, S., Mondala, T., Scanlan, C., Huflejt, M.E., Alvarez R., Bryan M.C., Fazio, F., Calarese, D., Stevens, J., Razi, N., Stevens, D.J., Skehel, J.J., van Die, I., Burton, D.R., Wilson, I.A, Cummings, R., Bovin, N., Wong, DC.H., and Paulson, J.C. (2004) Printed covalent glycan array for ligand binding proteins. Glycobiol.(13):846 Razi, N., and Varki, A. (1999) Cyptic sialic acid binding lectins in blook leukocytes can be unmasked my sialidase treatment or cellular activation. Glycobiol 9 (11):1225-1234 Varki, A., Brinkman-van der Linden, E., and Razi, N., (1998) SIGLECS: An expanding family of sialic acid binding I-type lectins with distinct expression patterns and complex functional regulation. International Carbohydrate Symposium, CP059 Razi, N., and Varki, A. (1998) Masking and Unmasking of CD22 lectin function in resting and activated B-Lymphocytes Proc. Natl. Acad.Sci USA 95:7469-7474 Razi, N, Varki, A., (1997) Regulation of the lectin function of CD22 during lymphocyte activation. Glycobiol., 7: 1038 Razi, N., Varki, A., (1997) Masking and unmaskin of the sialic acid binding lection function of CD22 during B Lymphocyte development and activation. Blood, 90, 455a Razi, N., and Lindahl, U., (1995) Biosynthesis of heparin/heparan sulfate. The D-glucasomminyl 3-O-sulfotransferase reaction; target and inhibitor saccharides. J. Biol. Chem. 270:11267-11275 Razi, N., Feyzi, E., Bjrk, I., Naggi, A., Casu, B., and Lindahl, U. (1995) Structural and functional properties of heparin analogs obtained by chemical sulphation of E. coli K5 capsular polysaccharide. Biochem J., 309:465-475 Razi, N., Kreuger, J., Lindahl, B., Lay, L., Panza, L., Russo, G., and Lindahl, U. (1995) Indentification of O-sulfate substituents on D-glucurionic acid units in heparin-related glycosaminoglycans using novel synthetic disaccharide standards. Glycobiol. 5:807-811 Razi N., (1995) Chemical and Enzymatic O-sulfation of Heparin-related polysaccharides. Functional and Regulatory Aspects. Uppsala University Press. Casu, B., Grazioli, G., Razi, N., Guerrini, M., Naggi, A., Torri, G., Oreste, P., Tursi, F., Zoppetti, G., and Lindahl, U., (1994) Heparin-like compounds prepared by chemical modification of capsular polysaccharide from E. coli K5. Carbohydr. Res. 263, 271-284 Casu, B., Grazioli, G., Hannesson, H., Jann, B., Jann, K., Lindahl, U., Naggi, A., Oreste P., Razi, N., Torri, G., Tursi, F., and Zoppeti, G. (1994) Biologically active, heparan sulfate-like species by combines chemical and enzymatic modification of the E.coli polysaccharide K5. Carbohydr. Lett., 1,107-114 |
| HOME | RESEARCH | PUBLICATIONS | GROUP MEMBERS | OTHER RESOURCES |