Paulson Laboratory
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James C. Paulson, Ph.D.
Cecil H. and Ida Green Professor and Chair
Department of Molecular Medicine
Affiliated with Department of Immunology & Microbiology
10550 North Torrey Pines Road, MB-212
La Jolla, CA 92037
858-784-9634 (phone)
jpaulson@scripps.edu


Spouse: Beverly Moore Paulson
Children: Lorien Mary, Erik Richard, Evan Carsten

PROFESSIONAL POSITIONS:
  • 2017 to present: Cecil H. and Ida Green Professor and Chair, Department of Molecular Medicine, Professor, Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA
  • 2015 to 2017: Cecil H. and Ida Green Professor and Chairman, Department of Cell and Molecular Biology, Professor, Department of Chemical Physiology, and Department of Immunology & Microbial Science, The Scripps Research Institute, La Jolla, CA
  • 2014 to 2015: acting President & CEO, The Scripps Research Institute, La Jolla, CA
  • 2013 to 2014: Chairman and Professor, Department of Cell and Molecular Biology, Professor, Department of Chemical Physiology, and Department of Immunology & Microbial Science, The Scripps Research Institute, La Jolla, CA
  • 1999 to 2012: Professor, Department of Chemical Physiology & Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA
  • 1996 to 1999: Vice President, Chief Scientific Officer, General Manager Glytec Division, and Member Board of Directors, Cytel Corporation, San Diego, CA
  • 1990 to 1996: Vice President Research Development and Member of Board of Directors, Cytel Corporation, San Diego, CA
  • 1985 to 1990: Professor and Vice-Chair, Department of Biological Chemistry, UCLA School of Medicine, Los Angeles, CA
  • 1981-1985: Associate Professor, Department of Biological Chemistry, UCLA School of Medicine, Los Angeles, CA
  • 1978-1981: Assistant Professor, Department of Biological Chemistry, UCLA School of Medicine, Los Angeles, CA
  • 1974-1978: Postdoctoral Fellow/Research Associate, Department of Biochemistry, Duke University Medical Center, Durham, NC


EDUCATION:
  • University of Illinois at Champaign-Urbana: Ph.D. (Biochemistry) 1974
  • University of Illinois at Champaign-Urbana: M.S. (Biochemistry) 1971
  • MacMurray College, Jacksonville, Illinois: A.B.(Chemistry/Biology) 1970


HONORS:
  • Prof. Avadhesha Surolia Award for Excellence in Glycobiology, Indian Institute of Alumni Association (IIScAA) 2023
  • Claude S. Hudson Award, American Chemical Society (ACS) 2023
  • Tamio Yamakawa Award, Japan Consortium for Glycobiology and Glycotechnology (JCGG) 2022
  • President's Innovator Award, Society for Glycobiology 2022
  • Alexander R Matzuk lecture, Drug Discovery - Baylor College 2022
  • American Association for the Advancement of Science (AAAS) Fellow 2016
  • Melville Wolfrom Award, American Chemical Society 2016
  • The Cecil H. and Ida Green Chair Award, The Scripps Research Institute 2015
  • Karl Meyer Award, Society for Glycobiology 2009
  • Bjivoet Medal, Bjivoet Center, Utrecht 2008
  • Barnett Lecture, Northeastern University 2008
  • United States EPA Green Chemistry Challenge Award 2000


PROFESSIONAL ACTIVITIES:
  • 2021 to Present: Co-founder and Scientific Advisory Board, Nighthawk Therapeutics
  • 2021 to Present: Scientific Advisory Board, NovAb Inc
  • 2021 to Present: Scientific Advisory Board, GlycoEra RGB
  • 2019 to 2020: Scientific Advisory Board, LimmaTech Biologics AG
  • 2019 to present: Scientific Advisory Board, Ansun Biopharma Inc.
  • 2017 to present: Chair, Scientific Advisory Board, Genomics Research Center, Academia Sinica, Taiwan
  • 2016 to present: Scientific Advisory Board, Palleon Pharmaceuticals
  • 2015 to 2021: Member, Scientific Advisory Board, Center of Excellence for Influenza Research and Surveillance-CEIRS
  • 2014 to present: Chair, Scientific Advisory Board, Canadian Glycomics Network (GlycoNet)
  • 2015 to 2015: Member, Advisory Board, Florida Inventors Hall of Fame
  • 2014 to 2015: Member Board of Directors, Sanford Consortium for Regenerative Medicine
  • 2013 to 2014: Elected/Chair, ACS Division of Carbohydrate Chemistry
  • 2011 to 2012: National Academy of Sciences Glycoscience Committee
  • 2008 to 2011: Scientific Advisory Board, Virdante, Inc.
  • 2006 to present: Scientific Advisory Board, BU Mass Spectrometry Resource, http://www.bumc.bu.edu/msr/
  • 2005 to present: Co-chair Human Glycomics/Proteomics Initiative (HGPI), https://www.hupo.org/human-disease-glycomicsproteome-initiative-hgpi/
  • 2004 to 2018: Scientific Advisor, Nexbio
  • 2004 to present: Scientific Advisory Board, Institute for Biological Sciences-IBS, National Research Council
  • 2003 to present: Scientific Advisory Board, Alberta Ingenuity Center for Carbohydrate Science-AICCS
  • 2002 to 2003: President, The Society for Glycobiology
  • 2001 to 2011: Director, Consortium Functional Glycomics, http://www.functionalglycomics.org
  • 1999 to 2010: Scientific Advisory Board, Neose Technologies Inc
  • 1996 to present: Honorary Member, American Society of Clinical Investigation
  • 1990 to present: Editorial Board, Glycobiology
  • 1990 to present: Member, American Chemical Society
  • 1980 to present: Member, American Society of Biological Chemists
  • 1979 to present: Member, Society for Complex Carbohydrates
  • 1989 to 1999: Scientific Advisory Board, Complex Carbohydrate Resource Center, Univ. Georgia
  • 1989 to 1991: NIH Study Section, Pathobiochemistry
  • 1986 to 1988: Scientific Advisory Board, Nucleic Acid Research Institute
  • 1985 to 1991: Editorial Board, Journal of Biological Chemistry


PATENTS AND PATENT APPLICATIONS:
  • Antigenic Compositions and Methods for using the same
    Reiko F. Irie, Tadashi Tai, Donald L. Morton, Leslie D. Cahan, James C. Paulson
    Patent issued: December 10, 1985; #4,557,931
  • Method for Producing Secretable Glycosyltransferases and other Processing Enzymes
    James C. Paulson, Eryn Ujita-Lee, Beverly Adler, Jeffrey K. Browne, Jasminder Weinstein
    Patents issued: July 16, 1991; #5,032,519; July 30, 1996, #5,541,083; July 7, 1998, #5,776,772
  • Process for Controlling Intracellular Glycosylation of Proteins.
    James Paulson, Eryn Ujita-Lee, Jasminder Weinstein
    Patent issued: September 10, 1991; #5,047,335
  • Use of Trans-sialidase and Sialyltransferase for Synthesis of Sialyl-2-3-betagalactosides
    Yukishige Ito and James Paulson
    Patent issued: April 4, 1995; #5,409,817
  • Intercellular Adhesion Mediators
    James Paulson, Mary Perez, Federico Gaeta, and Murray Ratcliffe
    Patent issued: May 19, 1998; #5,753,631
  • Antibodies to P-selectin and their uses
    Robert Chestnut, Margaret Polley and James Paulson
    Patent issued: September 1, 1998; #5,800,815
  • Compositions and Methods for the Identification and Synthesis of Sialyltransferases
    James Paulson, Dawn Wen, Brian Livingston, Bill Gilespie, Sorge Kelm, Kati Medzerhadsky, Alan Burlingham
    Patent issued: January 12, 1999; #5,858,751; October 5, 1999; #5,962,294
  • Method for Detecting the Presence of P-Selectin
    Robert Chestnut, Margaret Polley and James Paulson
    Patent issued: March 7, 2000; #6,033,667
  • Practical in vitro Sialylation of Recombinant Glycoproteins
    James Paulson, Robert Bayer, and Eric Sjoberg
    Patent issued: June 4, 2002; #6,399,336B1
  • Control of Immune Responses by Modulating Sialyltransferases
    Jamey Marth and James Paulson
    Patent issued: June 4, 2002; #6,376,475
  • High Affinity Siglec Ligands
    James C. Paulson, Brian Collins and Shoufa Han
    Patent issued: January 22, 2013; #8,357,671
  • Liposome targeting Compounds and Related Uses
    James C. Paulson, Weihsu Claire Chen, Norihito Kawasaki, and Corwin Nycholat
    Patent issued: May 3, 2016; #9,326,939
  • Compositions and Methods for Inducing Immune Tolerance
    James C. Paulson, Matthew Macauley, and David Nemazee
    Patent issued: December 20, 2016; #9,522,183; May 29, 2018; #9,981,023
  • Desensitizing Mast Cells by Co-Presentation of Antigens with High Affinity Mast Cell Siglec Ligands
    James C. Paulson, Shiteng Duan, Matthew Macauley, Corwin Nycholat
    Patent issued: May 04,2021; #10,994,006

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