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Vol. 11 (2011)


February

February 7, 2011

  • Scientists Reveal Key Mechanism Governing Nicotine Addiction
  • Team Converts Skin Cells to Beating Heart Cells
  • Natural Molecule Indirectly Prevents Stable Clot Formation
  • Scripps Research Awarded More than $3 Million
  • Kudos: Scripps Research Molecular Screening Center Work Leads to First Clinical Trial

January

January 31, 2011

  • Scripps Research Team Creates New Synthetic Compound with HIV-Fighting Promise
  • Scientists Find Measles' Natural Nemesis
  • Study Shows Map of Brain Connectivity Changes During Development
  • Scripps Research Appoints Noted Chemist to Florida Faculty
  • Kudos: Jeffery Kelly Named Emil Thomas Kaiser Award Honoree; AAI Recognizes Michael Oldstone with Mentoring Award

January 24, 2011

  • Scientists Reveal Complete Structure of HIV's Outer Shell
  • Team Identifies Genetic Abnormalities in Stem Cell Lines
  • Chemists Devise New Method to Quantify Protein Changes
  • Scripps Research and University of Pennsylvania Win $8 Million Grant to Develop Addiction Treatment

January 17, 2011

  • Scripps Research and Vanderbilt to Launch Joint Institute
  • Team Creates Novel Vaccine that Produces Strong Immunuty Against Cocaine High
  • Scientists Identify Key Interaction in Hepatitis C Virus
  • Study Uncovers Switch Controlling Protein Production
  • Kudos: Thomas Burris and Ehud Keinan Named AAAS Fellows; Raymond Moellering Awarded HHMI Damon Runyon Fellowship; Keary Engle Recognized as 2011 Cross Scholar

January 10, 2011

  • Team Develops Groundbreaking Technology to Detect Alzheimer's Disease
  • Study Reveals Unexpected Mechanism of New Multiple Sclerosis Treatment
  • Scientists Show Prions Mutate and Adapt to Host Environment
  • In Memoriam: Robert Nakamura (1927 - 2010)
  • Kudos: F1000 Ranks Patapoutian Lab Paper Among Top Five in Biology in 2010; Chemical & Engineering News Lists Baran Lab Work Among Top 2010 Achievements; Jin-Quan Yu Wins Novartis Early Career Award; Wendy Havran Awarded Honorary Doctorate from University of Copenhagen; Graduate Office Announces Merit Awards

Vol. 10 (2010)

December

December 20, 2010

  • Bi-Coastal Team Awarded $7.5 Million to Identify Potential Drug Candidates to Treat Nicotine Addiction
  • Scripps Florida Scientists Awarded $2.35 Million to Study New Obesity Treatment
  • Letter from the President: Year in Review
  • Kudos: Scripps Research Study Ranked Among Time Magazine's Top 10 Medical Breakthroughs for 2010; Cindy Ehlers Honored with Marsh Lectureship

December 13, 2010

  • Scientists Home In on Chemicals Needed to Reprogram Cells
  • Martha Fedor Named Editor-in-Chief of Journal of Biological Chemistry
  • Researcher Awarded Pair of Unconventional Grants
  • Kudos: ScrippsAssists Donates $750 to Torrey Pines State Reserve

December 6, 2010

  • Team Devises Broad New Technique for Screening Proteins
  • Scientists Redefine the Role of Plasma Cells in the Immune System
  • Scripps Florida Kicks Off Third Season of Front Lines of Hope Discussion Series
  • Kudos: Minghua Nie Wins NIH Award

November

November 22, 2010

  • Team Reports Molecular Structure of Dopamine Receptor
  • Scientists Identify First Synthetic Activator of Two Critical Proteins
  • Judy and J. John Goodman Support Scripps Florida
  • Kudos: Paul Kenny Selected for Jacob P. Waletzky Award; Claes Wahlestedt Receives Leadership Award at 2010 BioFlorida

November 15, 2010

  • Putting Down Roots: Franck Polleux Explores the Brain's Dynamic Beginnings
  • Scientists Identify New Mechanism Regulating Daily Biological Rhythms
  • SMART Teams Begin Year-Long Exploration of Molecules
  • Kudos: K. C. Nicolaou Wins Benjamin Franklin Medal in Chemistry; Sanja Arandjelovic Receives Arthritis Foundation Special Research Award HIV

November 8, 2010

  • Team Implicates Wayward DNA-Repair Enzyme in Friedreich's Ataxia
  • Scientists Find Nerve Cell Activity Drains Stem Cell Pool in Developing Brain
  • Kudos: Peter Schultz Wins $6.8 Million CIRM Grant; Susana Valente Awarded Grant from Landenberger Foundation to Study HIV

November 1, 2010

  • Team "Watches" Formation of Cells' Protein Factories for First Time
  • Finding the Rare Causes of Common Diseases
  • Kudos: Harry Orf Receives BioFlorida Leadership Award; Ming Chen Wins ACS Fellowship

October

October 25, 2010

  • Scientists Develop Novel Test that Identifies River Blindness Parasite in its Active State
  • Entire Issue of Scientific Journal Devoted to Multi-Institutional Center Headed by Scripps Research Scientists

October 18, 2010

  • Scientists Reveal First Structure of a Class of Proteins Guiding Blood Cell Movement
  • Study Challenges Conventional Theory of Modern Drug Design
  • Scripps Florida Scientists Awarded $3 Million NIH Grant to Accelerate Identification of Learning and Memory Genes
  • Kudos: M.G. Finn and Laurie Smith to Head Journal of Combinatorial Chemistry/ACS Combinatorial Science; SOF Announces Fall Research Symposium Prize Winners; Jared F. Purton Foundation to Hold First Annual Good On You 5K Charity Run/Walk

October 11, 2010

  • Scientists Reveal Structure of Dangerous Bacteria's Multidrug Resistance Pump
  • Researchers Shed Light on How Serotonin Works
  • Noted Neuroscientist Appointed to Scripps Research Faculty
  • Kudos: Sheng Ding Receives $1.5 Million Transformative Award to Investigate Stimulation of Neuron Regeneration in the Retina; Scripps Research Paper Makes "Most-Read" List; Tom Kodadek Named Innovator Finalist by South Florida Business Journal

October 4, 2010

  • Scripps Research Scientists Win $65 Million in New Grants to Reveal Form and Function of Important Proteins and Protein Complexes in Biology and Medicine
  • Scripps Research Names Innovative Chemist to Florida Faculty
  • Kudos: Gerald Edelman Receives Potomac Institute Navigator Award

September

September 27, 2010

  • Scientists Solve Long-Standing Mystery of Protein "Quality Control" Mechanism
  • Team Develops Molecular Test Providing a New Pathway for Identifying Obesity and Diabetes Drugs
  • Faculty Promotions: Jin-Quan Yu Named Full Professor; Mark Mayford, Pietro Sanna Receive Tenure

September 20, 2010

  • Scientists Identify Molecules Involved in Touch and Other Mechanically Activated Systems
  • New Study Suggests Changes in Diagnosis and Treatment of Malaria
  • Scripps Research Team Wins $5.1 Million to Develop DNA Sequencing Technology
  • In Memoriam: Keith McKeown (1945 – 2010)
  • Kudos: Geoffrey Chang Wins EUREKA Award

September 13, 2010

  • Team Discovers New Type of Anti-Malarial Compound
  • Scientists Discover the Mechanisms and Function of a Type of Mysterious Immune Cell
  • Researchers Identify New Gene for Memory
  • Scripps Research Appoints Douglas Kojetin to Florida Faculty
  • Kudos: Roy Smith Appointed Director with American Federation for Aging Research

August

August 30, 2010

  • Scientists Unveil Structure of Adenovirus, the Largest High-Resolution Complex Ever Found
  • Team Uncovers New Mechanism of Memory Formation
  • New Study Sheds Light on Painkilling System in Brain
  • New Graduate Students Arrive in Scripps Research Labs
  • Kudos: Scripps Research Named Among Top Institutions in Microbiology; Scripps Florida Grant Supports Advanced Technology; Daniel Bachovchin Wins California Breast Cancer Research Award; Christie Fowler Selected to Receive ACNP Travel Award; Barbara Suflas Noble Honored by South Florida Business Journal

August 16, 2010

  • Scientists Uncover Possible Cocaine Addiction Trigger
  • Distinguished University of Michigan Chemist Joins Department of Chemistry
  • Noted Biochemist Joins Department of Cancer Biology
  • Kudos: Dale Boger Named ACS Fellow; Senator George LeMieux Visits Scripps Florida; Interns Present Their Summer's Work

August 2, 2010

  • Study Opens the Door to Developing a New Class of Drugs for Treating Epileptic Seizures
  • Scientists Uncover Novel Anti-Diabetes Mechanism
  • Research Shows Infectious Prions Can Arise Spontaneously in Normal Brain Tissue
  • Snapshot: Research Associate Debbie Liao

July

July 19, 2010

  • Scientists Uncover Previously Unknown Natural Mechanism that Controls Cocaine Use
  • Noted Biochemist Joins Department of Chemistry
  • NIH Awards Team $2.3 Million Grant to Develop New Treatments for Drug Addiction

July 5, 2010

  • Institute Expands Summer Internship Programs
  • Scripps Research Scientists Share $2 Million in Florida State Research Grants
  • Snapshot: Vice President of Human Resources Cindy Scott-Lunau
  • Kudos: Julius Rebek Wins ACS Nichols Award; Loring Lab Collaboration Wins CIRM and Australian Grants; Jonathan Pokorski Wins NIH Pathway to Independence Award; Emily Plummer Honored by AWIS-SD; Tamas Bartfai's Drug Discovery: From Bedside to Wall Street Now Available in Mandarin

June

June 21, 2010
  • Scientists Determine Structure of Immune Molecule that Counteracts Many Strains of HIV
  • Team Finds a New Way to Attack Cancerous Cells
  • Luke Wiseman Sets Out to Understand How Cells Deal with Stress
  • Snapshot: Financial Reporting Manager Joe Calini
  • Kudos: Changchun Xiao Named Pew Scholar; Denis Malyshev and Zinaida Polonskaya Selected to Participate in Nobel Laureate Meetings; Phil LoGrasso Profiled on NIH Website

June 7, 2010

  • Scripps Research Institute Dedicates Dorris Neuroscience Center
  • Scientists Break Barrier to Creating Potential Therapeutic Molecules
  • Institute Awarded $6 Million to Develop Potential Therapies to Fight Alcoholism and Autism-Linked Syndrome
  • Snapshot: Controller Jared Machado
  • Kudos: Loren Parsons Receives Tenure; Kurt Wüthrich Named Foreign Member of The Royal Society; Phil Baran Wins Thieme-IUPAC Prize; Michael Oldstone's Viruses, Plagues, and History Named San Diego Book Awards Finalist; Keary Engle Wins NSF Student Scholars Program in Green Chemistry; Christine Crumbley Wins American Heart Association Fellowship

May

May 24, 2010

  • Scientists Find Chemical Signal from Predators That Sparks Fear in Mice
  • Team Discovers Body's Own Molecular Protection Against Arthritis
  • Kenan Charitable Trust Gives New $600,000 Grant to Continue Education Outreach Program at Scripps Florida
  • Kudos: California Breast Cancer Research Program Awards Two Grants to Felding-Habermann Lab; Francesca Cattaneo Wins Best Poster Award

May 17, 2010

  • Scripps Research Holds 18th Commencement
  • Study Overturns Decade-Old Findings in Neurobiology
  • Scientists Shed Light on Potential Treatment for Gaucher's Disease and Related Disorders

May 10, 2010

  • Scientists Solve Protein Structure Revealing Secrets of Cell Membranes
  • In Memoriam: Norman Klinman (1937 - 2010)
  • Team Provides Groundbreaking New Understanding of Stem Cells
  • Lessons on Life, Leadership, and Luck

May 3, 2010

  • Scientists Reveal How Genetic Mutations May Cause Type 1 Diabetes
  • Inaugural Event Showcases Research Talent of Scripps Florida Postdocs and Graduate Students
  • New NIH Grant Funds Development of Tests for Potential Obesity and Diabetes Treatment
  • Kudos: Karsten Sauer Wins Leukemia and Lymphoma Society Award; SF-SRF Announces ResearchFest Prize Winners

April

April 26, 2010

  • Scripps Research Scientists Solve Mystery of Fragile Stem Cells
  • New Study Helps Explain How We Can Sense Temperature
  • New Ranking from U.S. News & World Report Places Scripps Research Among Top Graduate Schools
  • Kudos: James Williamson Elected to American Academy of Arts and Sciences; Scripps Research Wins Bio-IT Best Practices Award; Claes Wahlestedt Elected Chair of FL CURED, Appointed to Research Advisory Council

April 16, 2010

  • New Nano-Tool Synthesized at Scripps Research
  • Team Finds Structure of Protein Important for Bacterial Virulence
  • Innovative Molecular Biologist Joins Scripps Florida
  • Kudos: Kevin Morris Wins Outstanding New Investigator Award; Karima Begriche Wins Endocrine Society Award; Four Kellogg School Students Receive NSF Fellowships; Sandra Schmid to Present NIH Lecture

April 5, 2010

  • Study Shows Compulsive Eating Shares Addictive Biochemical Mechanism with Cocaine, Heroine Abuse
  • Sanford Consortium Breaks Ground
  • How to Cope with Grief and Loss
  • Kudos: Floyd Bloom Gives Packard Lecture

March 29, 2010

  • Scripps Research Team Finds Structure of "Swine Flu" Virus
  • Richard and Helen DeVos Gift Kicks Off Drive to Endow Scripps Florida Graduate Program
  • Top Scientists Explore the Origin of Life in Lasker Lecture
  • Kudos: Julius Rebek Made Honorary Member of the University of Bonn Faculty

March 22, 2010

  • Susana Valente Enjoys the Best of Both Worlds
  • Moffitt Cancer Center and Scripps Florida Receive Grant to Create Bioengineered "Designer" Lymph Nodes
  • Seminar Challenges Participants to Reach for Their Dreams
  • Kudos: Peter Vogt Wins Szent-Györgyi Prize; Claes Wahlestedt Receives Carnegie Centenary Professorship Award

March 15, 2010

  • Light Activated "Warhead" Turns Modest Molecules into Super Protein Killers
  • Businesswoman and Community Leader Katherine Kennedy to Lead Scripps Research California Council
  • Scripps Research SMART Teams Showcase Work at High Tech Fair

March 8, 2010

  • Scientists Identify Age-Associated Defects in Schizophrenia
  • Scripps Research Hosts Prospective Students
  • Noted Learning and Memory Scientist Joins Neuroscience Department

March 1, 2010

  • Courtney Miller's Compass
  • Long-Distance Operator
  • Kudos: Philip LoGrasso Promoted to Full Professor; Martin Friedlander Wins 2010 Bressler Prize in Vision Science; Scripps Florida Intern's Photographs Featured at Hibel Museum of Art; Florida Community Lecture on Alzheimer's

February

February 22, 2010

  • Team Reveals How An Old Drug Could Have A New Use for Treating River Blindness
  • Business Executive and Former U.S. House Leader Richard A. Gephardt Elected to Lead Scripps Research Institute Board of Trustees
  • Scripps Florida and Gardens Mall "CELLebrate" Science
  • Going Green, Pound by Pound
  • Kudos: Landenberger Foundation Awards Three New Grants to Scripps Florida; Scripps Research Scientists Collaborate on New Lassa Fever Project; Alex Perryman Appointed to Chemical Biology & Drug Design Board

February 8, 2010

  • Scientists Find Two Compounds that Lay the Foundation for a New Class of AIDS Drug
  • Researchers Create Innovative New Way to Screen Libraries of 10 Million or More Compounds
  • Team Maps Epigenome of Human Stem Cells During Development
  • William Ja Joins Scripps Florida
  • Kudos: Daniel Popkin Wins Travel Award

February 1, 2010

  • Team Finds Stress Hormone Key to Alcohol Dependence
  • Scientists Find Potential New Way to Enhance Vaccines
  • Snapshot: Director of Education Dawn Eastmond
  • Kudos: Scripps Florida and Israel Cancer Association Collaborate for a Cure; Barbas Lab Paper Highlighted

January

January 25, 2010

  • Scientists Find Cancer Cells Co-opt Fat Metabolism Pathway to Become More Malignant
  • Team Identifies Novel Hepatitis C Inhibitorst
  • Scripps Research Books Face Time
  • Creating Your Low-Water Garden
  • Kudos: Gerald Joyce to Receive Stanley Miller Medal from National Academy of Sciences; Erica Ollmann Saphire and Marisa Roberto Honored at White House; Jennifer Busby Selected as One of Top "40 Under 40"

January 18, 2010

  • In Memoriam: Gary Bokoch (1954 – 2010)
  • Scripps Research Team Wins Global Race to Achieve Landmark Synthesis of Perplexing Natural Product
  • James Foley Joins Institute as Head of Florida Human Resources
  • On Press: In the World of Agonists and Antagonists, Something Inverse Comes Our Way

January 11, 2010

  • Scientists Show "Lifeless" Prions Capable of Evolutionary Change and Adaptation
  • Florida Philanthropists Phillip and Patricia Frost Give $1 Million to Scripps Florida
  • Team Develops Technique to Determine Ethnic Origin of Stem Cell Lines
  • A Sense of Balance in the Lograsso Lab
  • Kudos: Charles Weissmann Wins German Great Cross of Merit with Star; Jun Shi Selected to Receive Novartis Graduate Fellowship in Organic Chemistry

Vol. 9 (2009)

December

December 21, 2009

  • Scientists Crack Mystery of Protein's Dual Function
  • Letter from the President
  • Researchers Reveal Key Structure from Ebola Virus
  • In Memoriam: Jared Franklin Purton (1976 - 2009)
  • Kudos: Bruce Beutler Awarded Will Rogers Prize; Kim Janda Selected to Receive Honorary Degree from the University of Helsinki; Curt Wittenberg Elected Fellow of AAAS; Erica Ollmann Saphire Wins $1.2 Million NIH Award; Pat Griffin Wins $1.2 Million NIH Award

December 14, 2009

  • Team Restores Some Function to Cells from Cystic Fibrosis Patients
  • Elizabeth Fago Gives $1 Million to Scripps Florida
  • Researchers Uncover Chemical Basis for Extra "Quality Control" in Protein Production
  • Kudos: Sheng Ding's Stem Cell Breakthrough Named The Scientist's Top Innovation of 2009; Peter Wright Wins 2010 Stein and Moore Award; Wolfram Ruf Wins Recovery Act Grant; Graham Johnson Wins Prizes in "Celldance" Contest

December 7, 2009

  • Team Develops Cheap, Easy "Kitchen Chemistry" to Perform Formerly Complex Synthesis
  • Study Describes Powerful New Tool in the Fight Against Autoimmune Diseases, Blood Cancers
  • Noted HIV Researcher Joins Scripps Florida Faculty
  • Kudos: Scientists Receive Grant to Develop New Technologies to Monitor Protein Folding; Gerald Joyce Wins Dannie Heineman Prize; Changchun Xiao Awarded Lupus Research Institute Grant; Scripps Research Papers Highlighted

November

November 16, 2009

  • Team Shows Switching Between Sugary and Regular-Tasting Diet Can Activate Brain's Stress System and Lead to "Withdrawal" Symptoms
  • Making the Case for Zebrafish
  • Finding Flow
  • Kudos: Three Scripps Research Investigators Win DOD grants; Reza Ghadiri and Philip Dawson Receive du Vigneaud Awards

November 9, 2009

  • Floor Three: Synthesizing the Future of Scripps Florida
  • Stepping Up: Ann Hessell Receives a Ph.D. for Research in HIV
  • Bioentrepreneurship 101
  • Kudos: Jin-Quan Yu Wins Eli Lilly Grantee Award; Scripps Florida Receives Community Award

November 2, 2009

  • New Consortium Led by Scripps Research Scientists Awarded $10 Million by National Cancer Institute
  • Fish Story: Shuji Kishi Uses Zebrafish to Gain Insights into Aging
  • Teaching How to Learn
  • Kudos: Scripps Research Ranked Number One in Chemistry; Scripps Florida Construction and Design Wins Best of 2009 Award; Paul Kenny Wins Jarvik-Russell Young Investigator Award

OCTOBER

October 26, 2009

  • Team Reveals Secrets of Drought Resistance
  • A Major Step in Making Better Stem Cells from Adult Tissue
  • Consortium to Establish National Network of Scientists
  • Kudos: Bruce Beutler Elected to European Molecular Biology Organization; Crystal Moral Wins First Abrams Charitable Trust Award

October 19, 2009

  • Ronald Davis Joins Scripps Florida as Founding Chair of New Neuroscience Department
  • Team Awarded $3.9 Million Transformative Federal Grant to Develop New Compound Screening Platform
  • Florida Student Comes Home Twice
  • Kudos: Michael Pollard Selected to Give Randolph Memorial Lecture; Three Kellogg School Students Win NSF Fellowships

October 12, 2009

  • An Eye to the Future: Martin Friedlander Looks at Vision Loss
  • Scientists Make Advance Against Melanoma
  • Celebrity Golf Classic to Benefit Vision Research
  • Kudos: PATH Honors George Koob and Barbara Mason; SOF Announces Fall Research Symposium Prize Winners

October 5, 2009

  • Scientists Find Missing Piece of Powerful DNA Repair Puzzle
  • Scripps Florida Scientist Awarded $1.4 Million in Federal Stimulus Funds to Study Drug Targets in Alzheimer's, Alcoholism
  • A Patient Man: Enrique Saez Sets His Sights High

SEPTEMBER

September 28, 2009

  • Mechanism for Potential Friedreich's Ataxia Drug Uncovered
  • Scripps Research and IAVI Host Symposium to Launch Research Center
  • A Patient Man: Enrique Saez Sets His Sights High
  • Kudos: Graduate Students Win Prizes at Faculty Student Symposium

September 21, 2009

  • Rare Genetic Disease Successfully Reversed Using Stem Cell Transplantation
  • Rendina Family Foundation Grant to Spur Research on Glioblastoma
  • Kudos: Scripps Research Investigators Win NIH Recovery Act Funds

September 14, 2009

  • Two New Antibodies Found to Cripple HIV
  • Scientists Illuminate Structure of Circulating Lung Cancer Cells
  • Researchers Identify Genetic Cause for Type of Deafness
  • Donald Phinney Joins Scripps Research

AUGUST

August 31, 2009

  • Collaboration Aims to Reshape Addiction Therapy
  • Mentors Offer Helping Hand to Entering Students
  • Slideshow: Summer of Science

August 24, 2009

  • A Matter of Practicality: the Research of Laura Bohn
  • Team Definitively Ties Genetic Variations to Brain Size
  • Snapshot: Research Associate Scott Westenberger

August 10, 2009

  • Team Reports Breakthrough in Creating Live Mice from Skin Cells
  • Structure of Virus Protein Reveals How Viruses Hijack Cell Proteins
  • Scientists Find Early Evolution Maximized the "Spellchecking" of Protein Sequences
  • New Global Survey of Protein Regulation Sheds Light on Stem Cells Mechanisms

JULY

July 27, 2009

  • Scientists Uncover a New Immune System Protein
  • A Promising First-in-Class Drug Candidate
  • Researchers Discover Genetic Clues about Cancer Tumors

July 13, 2009

  • Scientists Find Key Culprits in Lupus
  • Study Points Way to Better Structure Modeling and Docking
  • Chris T. Sullivan and Leanna Landsmann to Lead Scripps Florida Council
  • Scripps Research Appoints Scott Forrest as Director of Business and Technology Development

JUNE

June 29, 2009

  • Scientists Uncover Novel Mechanism Controlling Tumor Growth in the Brain
  • Team Observes Human Neurodegenerative Disorder in Fruit Flies
  • Researchers Observe Single Protein Dimers Wavering Between Two Symmetrically Opposed Structures
  • Snapshot: Bill Young

June 15, 2009

  • Team Finds New Way that Cells Fix Damage to DNA
  • Goldstein Foundation Gives $1.5 Million to Scripps Research
  • Structure of the HIV Protein Shell Reveals Clues for New Therapies
  • Team Creates Simple Chemical System that Mimics DNA

June 1, 2009

  • A Potential New MS Treatment
  • Accelerated Method to Determine Infectious Prion Strains
  • Analysis Sheds Light on Protein Evolution
  • Snapshot: Executive Assistant Kathleen Ryan

MAY

May 18, 2009

  • Scripps Research Celebrates Commencement
  • Researchers Discover Molecular Defect Involved in Hearing Loss
  • Synthesis of an Important Chemical Class Simplified
  • 2009 Graduating Students

May 11, 2009

  • Scientists Determine Workings of Potentially Useful Virus
  • New Foundation Funds Scripps Research Team
  • Snapshot: Diane Wildman of Scripps Florida

May 4, 2009

  • First Technique for Producing Promising Anti-Leukemia Agent
  • Darwin in a Test Tube
  • Two Faculty Members Join Department of Metabolism and Aging

APRIL

April 27, 2009

  • A Major Breakthrough in Stem Cells from Adult Cells
  • Team Produces a Potential New Painkiller
  • Cancer Biology Wins More than $8 Million in Grants

April 20, 2009

  • Scientists Model 3-D Structures that Control Human Clock
  • Mimicry that Protects Genome Integrity
  • The Right Direction
  • 12 Easy Green Tips

April 6, 2009

  • Probing Puzzling Proteins with New Technique
  • JUST Fellow Brings Together Research and Teaching

MARCH

March 30, 2009

  • New Structure: Protein Contributes to Chemotherapy Resistance
  • Laura Bohn Joins Department of Molecular Therapeutics
  • Tribute Pages Put Money Where It Counts

March 23, 2009

  • Scientists "Watch" Alpha-Synuclein Proteins Change Shape
  • Cornerstones
  • The Nuclear Man

March 16, 2009

  • Scripps Research Scientists Mentor Students in New SMART Program
  • Team Identifies Key Molecules that Inhibit Viral Production
  • Ready For Prime Time

March 9, 2009

  • Scientists Engineer New Type of Vaccination that Provides Instant Immunity
  • Scripps Florida Opening in Photos
  • The Conqueror Worm
  • Team Deepens Fundamental Understanding of How Vaccines Work

March 2, 2009

  • Opening Ceremonies Celebrate New Scripps Florida Biomedical Research Facilities
  • Team Finds Immune Molecule that Attacks Wide Range of Flu Viruses
  • Scientists Develop General-Purpose Method for Detecting Trace Chemicals
  • Study Shows How Microscopic Changes to Brain Cause Schizophrenic Behavior in Mice
  • Team Establishes Vastly Improved Technique for Studying Critical Protein Group

FEBRUARY

February 23, 2009

  • First Crystal Structure of an Intermediate Particle in Virus Assembly
  • Premier Sponsors: Quantum Foundation, National City, and Florida Trend
  • Board of Trustees Elects Mark Pearson
  • New Technique Clears Path for Developing Drugs and Vaccines for Hemorrhagic Fever Diseases

February 9, 2009

  • Team Increases Understanding of Two Types of Blindness, Bolsters Simple Prevention Strategy, and Develops Gene Therapy Option
  • Scientists Identify a Mutation that Causes Inflammatory Bowel Disease
  • Scripps Research Appoints Three New Chemistry Faculty

February 2, 2009

  • Scientists Uncover Potential New Target for Schizophrenia Treatment
  • W. Mark Crowell Joins Scripps Research as VP, Business Development
  • Getting from Here to There

JANUARY

January 26, 2009

  • Team Finds Drug Lessens Body's Massive and Often Deadly Immune Response to Flu Virus
  • Argyrios Theofilopoulos Named Chair of the Department of Immunology and Microbial Science
  • Scientists Find Novel Use for Old Compound in Cancer Treatment
  • Snapshot: James Gohres

January 19, 2009

  • Team Develops New Technique to Tap Full Potential of Antibody Libraries
  • Scientists Find Cause of Cartilage Degeneration in Osteoarthritis
  • Researchers Discover New Structural Motif in Key Enzymes Is Essential to Prevent Autoimmune Disease
  • Leg Work on Hepatitis C

January 12, 2009

  • The Immortal Molecule
  • Quantum Leap Forward in Understanding Proteins
  • Stayn' Alive with Roy Smith

Vol. 8 (2008)

DECEMBER

December 22, 2008

  • Scientists Develop Method for Generating Novel Types of Stem Cells
  • Letter from the President
  • Next Generation Sequencing Comes to Campus
  • On Press: Phil LoGrasso's Quartet

December 15, 2008

  • Scientists Identify Cellular Fission Machine
  • Silencing Genes with Non-Coding RNAs
  • Gone in 80 Seconds
  • Kudos: CIRM Funds Ding, Barbas, and Loring Labs; Michael Conkright Awarded Landenberger Foundation Grant; The Scientist Selects Chun Lab Research as "Hot Paper"; Genome Technology Magazine Names Kevin Morris "Tomorrow's PI"

December 8, 2008

  • Team Defines New Painkilling Chemical Pathway
  • Scripps Florida Scientists Find Blocking a Receptor Significantly Decreases Nicotine Addiction
  • Scientists Shed Light on How DNA Is Unwound So That Its Code Can Be Read
  • Generous Gifts Make Possible Merit Awards for Graduate Students
  • Hirsch Index Shines Spotlight on Scripps Research Chemists

NOVEMBER

November 24, 2008

  • Touch and Go
  • Scientists Discover New Cause of Fatal Brain Injury from Acute Viral Meningitis
  • Researchers Identify Blood Component that Turns Bacteria Virulent

November 17, 2008

  • San Diego Philanthropist John Moores Gives $2.1 Million to Scripps Research
  • Scientists Uncover New Mechanism Closely Linked to Neurodegeneration and Alzheimer's
  • Are You Ready for the Big One?

November 10, 2008

  • Scientists Identify Exciting New Compounds for Stem Cell Production from Adult Cells
  • New Sculpture Portraying Human Antibody as Protective Angel Installed on Scripps Florida Campus
  • Trustees Fund Graduate Student Fellowships

November 3, 2008

  • Scientists Develop A New Strategy to Fight Obesity
  • Scripps Florida Group Awarded $1.5 Million to Fight Major Water and Food Parasites
  • ScrippsAssists Looks Ahead to the Holidays
  • Kudos: Michael Hanson Wins Sidhu Award

OCTOBER

October 27, 2008

  • Hollis Cline Explores How Brain Circuits Are Built
  • Scientists Enhance Immune System Attacks on Cancer
  • Smart Commuting
  • Kudos: Scripps Florida Receives Innovation and Entrepreneurialism Award

October 20, 2008

  • New Way to Limit Damaging Production of Nitric Oxide
  • Researchers Shed Light on Immune System Suppression
  • Office of Career and Postdoc Services Welcomes Feedback
  • Kudos: Bruce Beutler Elected to Institute of Medicine; Albert Eschenmoser Wins Karrer Medal; Valery Fokin Wins Synthetic Organic Chemistry Award

October 13, 2008

  • In Memoriam: Ernest Beutler (1928 — 2008)
  • Team Solves Structure of "Beneficial" Virus
  • Scientists Pinpoint New Cancer Stem Cell Links to Chemotherapy Resistance
  • Service Awards Celebrate Long-Time Employees

October 6, 2008

  • Scripps Research and IAVI Launch World's First Dedicated HIV Neutralizing Antibody Center
  • Scientists Define Structure of Important Neurological Receptor, Establishing a Platform to Understand G Protein-Coupled Receptors
  • Study Unveils Structural Details of Enzyme Vital to DNA Repair
  • Open Enrollment News

October 6, 2008

  • Scripps Research and IAVI Launch World's First Dedicated HIV Neutralizing Antibody Center
  • Scientists Define Structure of Important Neurological Receptor, Establishing a Platform to Understand G Protein-Coupled Receptors
  • Study Unveils Structural Details of Enzyme Vital to DNA Repair
  • Open Enrollment News

SEPTEMBER

September 29, 2008

  • Exploring "Molecules That Changed the World"
  • The Flow: Jennifer Busby Harnesses the Power of Mass Spectrometry
  • Ernest Beutler Steps Down as MEM Chair; Jeffery Kelly to Assume Position
  • Kudos: Scripps Research Hosts Stem Cell Course

September 22, 2008

  • Team Reverses Huntington's Disease Symptoms in Mice
  • Researchers Find Gene Critical to Normal Hearing
  • Alex Bruner Joins Scripps Florida Philanthropy
  • Kudos: David Millar Promoted to Full Professor; Bruce Torbett Receives Tenure Claudio Joazeiro Wins American Cancer Society Grant; Five Students Selected for ARCS Fellowships

September 15, 2008

  • A Lab with a View: Tom Bannister Looks for Potential New Drugs
  • NWIS Recharges
  • Forever Summer for Scripps Research Interns
  • Kudos: Carlos Barbas Wins ACS Cope Scholar Award; Gaudenz Danuser Honored with Bárány Award for Young Investigators; Antonio Amelio Wins National Cancer Institute Award; Graduate Program's September Symposium Features Outstanding Presentations

September 8, 2008

  • Scripps Research Receives Record Federal Grant of More than $80 Million
  • Scientists Find Gene Expression Profile Shared by Pluripotent Stem Cells
  • Study Topples the One Drug–One Disease Paradigm for Combating Protein-Folding Diseases
  • Kudos: Carlos Barbas Wins Tetrahedron Young Investigator Award; Ben Cravatt Wins EUREKA Award

AUGUST

August 25, 2008

  • Probing the Proteome
  • New Protein Survey Upends Understanding of Cell Death Process
  • Sampling Life in the Lab
  • On Press: Small Changes in an Antibody Binding Site Can Completely Alter Protein Activity
  • Snapshot: Joe Bartoe of the Office of Research Grant Development

August 11, 2008

  • New Study Solves Structural Mystery of Cellular Protein Transport
  • A Novel Algorithm Makes Accurate Single-Molecule Tracking a Desktop Reality
  • Team Unravels New Cellular Repair Mechanism
  • Lawrence Wylie to Head Scripps Florida Environmental Health and Safety
  • Kudos: Office of Philanthropy Announces New Awards; Johanna Heideker Receives Boehringer Ingelheim Fonds Fellowship; Amanda Blasius Wins Cancer Research Institute Support; Jonathan Hollander Wins Young Investigator Travel Award

JULY

July 28, 2008

  • The Globalist: Jun-Li Luo Tracks a Novel Approach to Cancer Therapy
  • Scientists Find Modified Protein Containing an Unnatural Amino Acid that Breaks Immune Tolerance
  • Researchers Detail Kinetic Mechanism of Kinase Linked to Diabetes
  • Kudos: Sandra Schmid Wins ASBMB Award for Research and Teaching

July 14, 2008

  • Scientists Reveal Critical Structure from Ebola Virus
  • Scripps Florida Researchers Find New Clue to Alzheimer's Disease
  • Bi-Coastal Collaboration Uncovers Novel Activators of Key Cell Receptors
  • Chris Liang Blazes a Trail
  • Kudos: Andrea Nold Wins Bristol-Myers Squibb Fellowship; Pick-Wei Lau Wins American Heart Association Fellowship

JUNE

June 30, 2008

  • Disease-Causing Mutations Reveal Surprising Pattern
  • Pathogen Uses Unique Strategy to Inhibit Human Immune Response
  • Researchers Shed Light on Molecular Pathways of Alcohol Addiction
  • Amin J. Khoury Elected to Scripps Research Board
  • Kudos: Jeanne Loring Wins Millipore Grant; Ian J. MacRae Selected as Pew Scholar; Kuhn Lab Brings Home Microsoft Innovation Award; Image by Bob Turner Selected for Exhibitition

June 16, 2008

  • Research Unveils New Stabilizing and Signaling Properties of Cholesterol in Key Human Receptors
  • Scientists Discover Synthetic Chemicals that Create Pluripotent Stem Cells from Adult Cells
  • Jeffery Kelly, Jamie Williamson Assume New Leadership Roles
  • Kudos: Tom Maimone Honored with Roche Award of Excellence; BIOCOM Education Committee Wins Partnership Award; Endeavor Magazine Wins Top Honor; Scientific Art on the Go

June 2, 2008

  • NIH Awards $20 Million CTSA Grant to Scripps Translational Science Institute
  • Crystal Structure Reveals Mystery Behind Three Rare Childhood Disorders
  • Scientists Find Seizure Drug Reverses Cellular Effects of Alcohol Addiction in Models
  • New Patent Covers Broad Class of Promising Chemical Reactions
  • Kudos: Scripps Research Chemistry Papers Rank Number One for Impact; Burton, Nemazee Receive Funding in AIDS Vaccine Initiative; Tellinghuisen Wins Burroughs Wellcome Award; Hu Awarded Life Science Research Foundation Fellowship; Steinmetz Wins AHA Fellowship; Lee Receives Two Travel Awards

MAY

May 19, 2008

  • Scripps Research Celebrates 16th Commencement
  • Team Devises Innovative Method to Produce Highly Sought-After Drug
  • A New Slap Against Malaria
  • 2008 Graduating Students

May 12, 2008

  • Anton Maximov Connects with the Science of the Synapse
  • New International Agreement Advances Study of Alcoholism
  • On Press: New Test Helps Identify Cancer Drug Candidates

May 5, 2008

  • Scientists Identify Protein Critical for Iron Absorption
  • Scripps Florida Receives Grant to Improve and Expand Science Teaching
  • On Press: New Method for Spotting Critical Cancer Drivers
  • Kudos: Bruce Beutler, Michael Oldstone, and Peter Wright Elected to National Academy of Sciences; Hugh Rosen Elected to Association of American Physicians; Nicole Steinmetz Wins Travel Award

APRIL

April 28, 2008

  • T Cell Multiplication Unexpectedly Delayed After Infection
  • Intern Success Stories in the Making
  • Molecule of the Month Celebrates 100th Image
  • On Press: Scripps Florida Scientists Develop New Way to Speed Research on Estrogen Receptors

April 21, 2008

  • Fundamental Questions: An Interview with Albert Eschenmoser
  • Scientists Automate Molecular Evolution
  • Small RNAs May Play Big Role in Embryonic Stem Cells
  • On Press: The Sweet Side of Viruses
  • Kudos: Gerald Dodson and Michelle Duquette-Huber Win NIH Awards

April 7, 2008

  • A Ghost in the House: Paul Kenny Works to Understand the Mysteries of Addiction
  • New Program Unites Neuroscience Talent at Scripps Research
  • Mobility Pond Makes a Splash
  • Kudos: Jonathan Hollander Wins NIH Awards

MARCH

March 31, 2008

  • Renowned Researcher Jeanne Loring Heads New Stem Cell Center at Scripps Research
  • The Secret Life of Stem Cells
  • Snapshot: Senior Director of Research Computing Jason Sausser
  • Kudos: Brooke Miller Wins Young Investigator Awards

March 24, 2008

  • Scientists Develop Process to Disrupt Hepatitis C Virion Production
  • Scripps Research Team Wins $4 Million Grant to Study Effects of Chronic Marijuana Use
  • Snapshot: Research Associate Olivier Harismendy
  • Kudos: Albert Eschenmoser Wins Benjamin Franklin Medal; Richard Lerner Receives Builders of Science Award

March 17, 2008

  • Scientists Identify Potential New Target for Treating Metastatic Cancer
  • Scripps Florida Awarded $7.6 Million Grant to Develop Novel Treatments for Parkinson's Disease
  • Flexible, Top-Ranked Program Attracts Future Graduate Students
  • Kudos: Ian Wilson Honored Three Times; Three Barbas Papers Make "Most-Cited" List

March 10, 2008

  • Scientists Devise Approach that Stops HIV at Earliest Stage of Infection
  • Scripps Research Scientists Launch International Conference on Alcoholism and Stress
  • A Beautiful Friendship: Scripps Research Hits It Off with the Fleet Science Center

March 3, 2008

  • A Bigger Picture: Peter Kuhn Looks at Circulating Tumor Cells
  • Scientists Studying Sepsis in Mice Find Potential Drug Targets for Deadly Disease
  • Bright Lights: Mystery of Glowing Antibody Solved by Scripps Research Scientists

FEBRUARY

February 25, 2008

  • Diamonds and Pearls: Ernest Beutler Celebrates Milestones
  • Study Uncovers New Mechanism of Long-Term Memory Formation
  • Scientists Find Protein May Protect Against Alzheimer's Disease
  • Kudos: Travis Young Wins Lesly Starr Shelton Award

February 11, 2008

  • In Memoriam: Frank J. Dixon, 1920-2008
  • Calcium Channel Blockers Help Normalize Cells Derived from Patients with Lysosomal Storage Disease
  • On Press: Team Finds Genetic Mutation May Lead to Increased Autoimmunity Learning to Lead
  • Kudos: Jeffery Kelly Wins Vincent du Vigneaud Award

February 4, 2008

  • Medicine Man: Philip LoGrasso Targets Drug Discovery
  • A Brand-New Mulan Makes Her Debut
  • Kudos: Enrique Saez Wins American Diabetes Association Award

JANUARY

January 28, 2008

  • Scientists Discover New Gene Linked to Fragile X Syndrome
  • Team Develops New Method for Creating Self-Assembling, Nanoscale Materials
  • Snapshot: Research Associate Hao Jiang
  • Kudos: Kendall Nettles Wins American Cancer Society Grant

January 21, 2008

  • Scientists Find New Genetic Mutation that Halts the Development of Lupus
  • Phillip and Patricia Frost Give $1 Million to Scripps Florida
  • Naturally Occurring Peptide Inhibits Common Viral Infection

January 14, 2008

  • Team Finds a Widely Used Anti-Malarial Drug Prevents Cancer Development
  • Scripps Research Discovery Leads to Broad Potential Applications in Biotech Deal
  • Scientists Discover Remarkable Editing System For Protein Production
  • On Press: Molecular Graphics and Music of the Spheres
  • Kudos: Sarah Tully Wins Damon Runyon Fellowship; Carrie Arnold and Urtzi Garaigorta Awarded Cancer Research Institute/Irvington Institute Fellowships

Vol. 7 (2007)

DECEMBER

December 17, 2007

  • Team Identifies Human Antibodies that Prevent Hepatitis C Virus Infection in Mouse Model
  • White Blood Cells Deliver Boost to Tumors
  • Pun and Games with Richard Lederer
  • Kudos: Ding, Baldwin Win CIRM New Faculty Awards; Pendyala Awarded Fellowship for ALS Research; Mitro Receives Career Development Grant; Canosa Wins Marie Curie Actions Fellowship

December 10, 2007

  • Scientists Discover Chemical Triggers for Aggression in Mice
  • New Test Identifies Lethal Prion Strains Quickly and Accurately
  • New Online Service Expands Job Search Options for Students, Postdocs
  • Kudos: Richard Lerner Wins Builders of Science Award; Jessica Raushel and Benjamin Pratt Awarded Eli Lilly Fellowships

December 3, 2007

  • New Research Identifies a Novel Receptor and Potential Target to Prevent the Sexual Transmission of HIV-1
  • New Online Service Expands Job Search Options for Students, Postdocs
  • Generous Gifts Make Possible Merit Awards for Graduate Students
  • Kudos: Ernest Beutler Honored with First Wallace H. Coulter Award; Cindy Ehlers Wins 2007 Thurman Award

NOVEMBER

November 19, 2007

  • Scientists Develop Modeling Method that Increases Our Understanding of Diseases like Cystic Fibrosis and Alzheimer's
  • MySci Opens Doors to Science
  • New La Jolla Lecture Series Reaches Out to Institute's Donors and Friends

November 12, 2007

  • Failure is Not an Option: Ray Stevens Pursues a High-Risk, High-Return Strategy
  • A New, More Complex Role for a Major Component of Cell Migration
  • Snapshot: Wendy Keeney, vice president of Philanthropy

November 5, 2007

  • Team Blocks Bacterial Communication System to Prevent Deadly Staph Infections
  • Scientists Shed Light on Stabilization Dynamics of Important Nuclear Receptor
  • Luncheon Honors ScrippsAssists Volunteers
  • Kudos: Geza Ambrus-Aikelin Wins California HIV/AIDS Research Award

OCTOBER

October 29, 2007

  • Scripps Research Wins $51 Million to Study Critical Immune Response Mechanisms
  • California Campus Returns to Work After Fires
  • Service Awards Celebrate Long-Time Employees
  • Kudos: Benjamin Cravatt Elected as AAAS Fellow

October 22, 2007

  • Inventing New Chemistry: William Roush Explores Strategies Against Tropical Diseases
  • The Goldilocks Scenario and Alzheimer's Disease
  • Snapshot: Research Associate Florent Martin

October 15, 2007

  • Structure of HIV Capsid Protein Reveals Potential Weakness at Inner Core of Virus
  • Novel Yeast Protein Plays a Key Role in Repairing Double-Strand DNA Breaks

October 8, 2007

  • Scientists Develop Innovative Dual Action Anthrax Vaccine-Antitoxin Combination
  • Study Reveals Mechanism Behind Nicotine Dependency
  • Snapshot: Senior Machinist/Plastics Fabricator Chris Fish

October 1, 2007

  • Tales from a Life in DNA
  • New Center for Physiological Proteomics Aims to Transform Diagnosis and Treatment of Disease

SEPTEMBER

September 24, 2007

  • Pearson Family Chair to Support Forward-Looking Alcohol and Addiction Research
  • Snapshot: Senior Administrative Assistant Kathy Sterling

September 17, 2007

  • Researchers Shed New Light on How Antibodies Fight HIV
  • Scientists Reveal Pivotal Hearing Structure
  • Kudos: Chi-Huey Wong Wins Humboldt Research Award; Michael Zwick Receives Young Investigator Award; Tucker Roberts Awarded ACS Medicinal Chemistry Fellowship

September 10, 2007

  • Researchers Pinpoint Specific Neurons Involved In Memory Formation
  • Study Reveals Prion Disease Culprit
  • New Protein Family Provides Unexpected Link Between Two Regulatory Pathways
  • Scripps Research Lab Hosts Breast Cancer Science Training
  • Kudos: Bruce Beutler Wins Balzan Prize; Ang Li Awarded Bristol-Myers Squibb Fellowship; Andrea Nold Selected for ACS Fellowship

AUGUST

August 27, 2007

  • Physicist in Disguise
  • Scientist for the Summer
  • A Special Gift
  • Kudos: Maimone and Richter Win Bristol-Myers Squibb Fellowships; Cho Awarded Schlumberger Faculty for the Future Grant; Johnson Receives National Eye Institute Award; Udit Wins Canadian Fellowship; Dambacher Awarded Grant for Unnatural Amino Acid Study

August 13, 2007

  • Building on Success: Cindy Ehlers Extends Innovative Research on Alcoholism
  • Team Identifies a New Mechanism That Extends Lifespan of a Nematode
  • New Chemical Tool Captures Previously Unseen Molecules
  • Key Protein Deficiency Leaves Mice Hypersusceptible to Viral Infection
  • Kudos: Andrew Saphire Awarded Center for Aids Research Grant

JULY

July 30, 2007

  • New "Checkmate" Method Provides Powerful Tool for Preventing Spread of Future Epidemics
  • In Memoriam: Daniel Koshland, Jr. (1920-2007)
  • Renowned Chemist Roy Periana Joins Scripps Florida

July 16, 2007

  • The Song Remains the Same in the Wong lab
  • Study Links Chronic Metamphetamine Abuse and Cardiovascular Disease
  • Snapshot: Research Associate Vandana Ramachandran

July 2, 2007

  • From Discovery to Medicine: An Interview with Eric Topol
  • Scientists Show Protein Accelerates Breast Cancer Progression in Animal Models
  • Team Discovers Mouse Appetite Suppressant
  • Kudos: Lerner Receives Honorary Degree from Oxford; Baldwin Wins Pew Scholarship; Teixeira Named Pew Latin American Fellow; Nicola Receives ACS Fellowship; Beierle Awarded NASA Funding; Whitby Selected for Andrea Elizabeth Vogt Memorial Award

JUNE

June 18, 2007

  • Memento: Exploring the Mysteries of Memory
  • Stem Cells Forward and Back
  • Norma and Frank Sugg Leave Legacy for Leukemia Research

June 4, 2007

  • Team Awarded $17 Million Grant to Develop Therapeutic Use of Adult Stem Cells to Treat Eye Diseases
  • Study Reveals Process Linking Disordered Protein Folding and Binding
  • How to Avoid a Heart Attack
  • Kudos: Benjamin Cravatt Wins Gill Center Young Investigator Award

MAY

May 21, 2007

  • Scripps Research Holds 15th Commencement
  • Team Discovers Critical Component in the Progression of Inflammation

May 14, 2007

  • Understanding Atherosclerosis as "Inflammation Gone Bad"
  • New Study Reveals Mechanism Vital to Cell Division Regulation
  • Hot Topz Celebrates "Real World Heroes"
  • Kudos: Clare Waterman-Storer Wins Sackler International Prize in Biophysics, Dorian McGavern Wins Burroughs Wellcome Fund Prize

May 7, 2007

  • Mixing Basic and Applied Research: An Interview with John Cleveland
  • Study Reveals Little-Known Cell Networks Vital to Circadian Rhythm
  • Team Sheds Light on Long-Sought Cold Sensation Gene

APRIL

April 30, 2007

  • On Genetics: An Interview with Bruce Beutler
  • Study Shows Humans and Plants Share Common Regulatory Pathway
  • Cancer-Specific Mutations May Offer Path to Treatment

April 23, 2007

  • Playing to Win: An Interview with Ian Wilson on Project Checkmate
  • Scripps Research Team Unravels Drug Target for Parasitic Diseases
  • New Fellowships Provide Mentored Teaching Experience

April 9, 2007

  • Making Life Difficult for Viruses
  • New Regulatory Mechanism for Critical Protein Signaling Domain
  • Major Role for Novel Neurotransmitter System in Regulating Drug Intake
  • Scripps Florida Forms Molecular Therapeutics Department
  • Kudos: Francis Chisari Wins Distinguished Scientist Award; Charles Surh Honored with Ho-Am Medicine Prize

April 2, 2007

  • A Place Called Discovery
  • Opening the Door to Science
  • Snapshot: Daphne Lurie

MARCH

March 26, 2007

  • Team Dramatically Simplifies Synthetic Production of Potential Pharmaceuticals
  • Pardon Our Dus

March 19, 2007

  • Forty Years Young
  • Science on Display
  • Scripps Research Partners with Fleet Museum for Two Events

March 12, 2007

  • Ceremony Dedicates Scripps Florida Campus
  • The Joy of Measurement: John Yates Advances Mass Spectrometry
  • Scripps Research Racks Up Stars from Charity Navigator
  • Kudos: Paul Schimmel Wins Stein and Moore Award

March 5, 2007

  • The Mountaineer: Kristin Baldwin Explores New Territory
  • New Monoclonal Antibody Destroys Methamphetamine In Vitro
  • Kudos: Barbas Lab Papers Top Most-Cited List; Evelyn Griffin Wins Image Contest; Kiyomi Komori Wins Jairo Arévelo Fellowship

FEBRUARY

February 26, 2007

  • Chemical Pathway Causes Mice to Overeat and Gain Weight
  • Structure May Be Key to AIDS Vaccine Development
  • Structural Dynamics of Single Prion Molecules
  • Board Business: Promotions, Recognition
  • Kudos: Richard Lerner to Receive Honorary Degree; Schultz Lab Awarded New Grant; Ehlers Group to Study Drinking Prevention; Ryan Shenvi Wins Lesly Shelton Award

February 12, 2007

  • Compounds Show Significant Promise Against Potential Bioweapon Toxins
  • New Symposium Offers Insights into Scientific Leadership and Lab Management
  • In Memoriam: Charles E. Scripps, Sr. (1920 - 2007)

February 5, 2007

  • Study Reveals New Activation Mechanism for Pain Sensing Channel
  • Genetic Variation Found to Protect Some Afro-Trinidadians from Alcoholism
  • Snapshot: Research Associate Ron Nepomuceno
  • Kudos: Laura White Receives Bagel Fellowship; Chemistry Department Hosts 18th Frontiers in Chemistry Symposium

JANUARY

January 29, 2007

  • Study Reveals New Function of Protein Kinase Pathway in Tumor Suppression
  • Cycling for a Cure
  • Kudos: Phil Baran Wins National Fresenius Award; Dale Boger Receives Ernest Guenther Award; Benjamin Cravatt Selected as 2007 Irving Sigal Young Investigator

January 22, 2007

  • Combination Therapy Obliterates New Vessel Growth in Tumors and Retinopathy
  • Study Reveals Dynamic Interface of Molecular Clutch in Cell Migration
  • ARCS® Foundation Supports Kellogg School Students

January 15, 2007

  • Study Questions Need for Potential Vaccine Additive
  • Glucose "Sensor" Plays Dual Role in Glucose Metabolism and Fat Synthesis
  • WASC Congratulates Kellogg School on "Exemplary" Proposal

 

Vol. 6 (2006)


DECEMBER

December 18, 2006

  • Study Reveals Molecular Basis of Botulism Toxin's Deadly Activity
  • Father Cycles Coast-to-Coast to Rally Support Against Rare Disorder
  • Snapshot: Chris Ochoa

December 11, 2006

  • Focusing on What's Important
  • Laugh the Stress Away
  • Snapshot: Tom Chanthaoudom

December 4, 2006

  • A Stitch in Time
  • Scripps Research and Pfizer Enter Five-Year, $100 Million Collaboration
  • Snapshot: Lois Yamada

NOVEMBER

November 20, 2006

  • Trapped in the Folding Machine
  • Scientists Identify Cells That Promote Repair of Blood Vessels in the Eye
  • Slideshow: X-Sci/2006 Celebrates Science

November 13, 2006

  • Building a Bridge from Basic Science to New Therapies: An Interview with Patrick Griffin
  • Changing of the Guard at the Society of Fellows
  • Snapshot: Peter Policastro

November 6, 2006

  • Reduced Body Temperature Extends Lifespan in Scripps Research Study
  • Scientists Identify Synthetic Compound That Keeps Stem Cells Young

OCTOBER

October 30, 2006

  • Study Offers Innovative Profile of Enzyme That Aids Tumor Growth
  • Snapshot: Stephanie Cherqui

October 23, 2006

  • A Good Year
  • Study Shows How Genetic Repair Mechanism Helps Seal DNA Breaks

October 16, 2006

  • Two Steps Forward
  • Neuroscience Blueprint Awards Grants to Scripps Research Scientists
  • Snapshot: Rashid Ali

October 9, 2006

  • Friends in High Places
  • Coping with Life's Transitions
  • Snapshot: Adam Mullick

October 2, 2006

  • Twice Told Tales
  • $38 Million Grant Awarded to Alcohol Research Consortium
  • Snapshot: Hollie Alkema

SEPTEMBER

September 25, 2006

  • Study Details Structural Changes of a Key Catalytic Enzyme
  • Faculty Promotions Announced
  • Snapshot: Deborah Leach-Scampavia

September 18, 2006

  • Graduate Program Retreat Looks to Next Generation of Leading Scientists
  • New Study Pinpoints Unique Genetic Susceptibility for Viral Encephalitis
  • Scripps Research, McDonald's Align to Fight Childhood Obesity and Type 2 Diabetes

September 11, 2006

  • Study Unveils Structure of Key Component of Antibiotic Resistant Bacteria
  • Consortium for Functional Glycomics Awarded $40.7 Million "Glue" Grant
  • Biomedical Graphics Introduces Videoconferencing Service
  • On Press: Enzyme Builds Neurotransmitters Via Newly Discovered Pathway

AUGUST

August 28, 2006

  • Scripps Research Team Reverses Friedreich's Ataxia Defect in Cell Culture
  • Marijuana's Active Ingredient Shown to Inhibit Primary Marker of Alzheimer's Disease
  • Slideshow: A Season of Science

August 14, 2006

  • Scripps Research Scientists Successfully Test New Anti-Obesity Vaccine
  • Research Team Discovers Age-Related Cellular Activities that Protect Against Protein Aggregation
  • Snapshot: Mohammad Fallahi
  • On Press: Study Shows Newly Discovered Genetic Abnormality Causes Acute Myeloid Leukemia

JULY

July 31, 2006

  • Quantum Leap
  • Researchers Unveil Strategy for Creating Actively Programmed Anti-Cancer Molecules
  • Snapshot: Linda Lukasiewicz

July 17, 2006

  • Scientists Show Prion Disease Agent Can Cause Heart Damage
  • Appointments of Dean of the Faculty and Dean of Graduate and Postgraduate Studies
  • Meeting with Jimmy Carter Energizes Research Team
  • On Press: Researchers Use New Chemical Probe to Manipulate Protective Inner Barriers

July 3, 2006

  • Researchers Map Infectious Hepatitis B Virus
  • Biogen Idec Foundation Funds Teacher Interns
  • Snapshot: Mario Osornio

JUNE

June 19 , 2006

  • Blood Work
  • Study Points to Genes Responsible for Malaria Parasite's Survival in Face of Attempts to Eradicate It
  • Snapshot: Reuben Mitchell

June 5, 2006

  • Study Suggests Virus Uses Pressure to Sense when Full of DNA
  • Researchers Link Effects of Withdrawal to Compulsive Drug Use and Craving
  • John J. Moores Elected Chair of Board of Trustees

MAY

May 22, 2006

  • Scripps Research Holds 14th Commencement
  • Study Details Hepatitis C Ability to Block Immune System Response
  • Scientists Reveal Signaling Pathways for Expansion of Pancreas Stem Cells

May 15, 2006

  • Still on the Case
  • Everything You Always Wanted to Know About Presentations (But Were Afraid to Ask)

May 8, 2006

  • Study Results Offer Guidance in Treatment of Alcohol Dependence
  • Structures on the Fast Track
  • Scientists Reveal Structure of E. coli Multidrug Transporter Protein

May 1, 2006

  • Immune Response to HIV in the Brain a "Double-Edged Sword"
  • Scientists Develop Improved Medium for Stem Cell Growth and Differentiation
  • Structure Yields Insights into Werner's Syndrome, Aging, and Cancer
  • Snapshots: Marcia McRae

 

APRIL

Lack of a Key Enzyme Dramatically Increases Resistance to Sepsis (04/24/06)
Study Shows Gene Candidates for Predisposition to Alcohol Abuse (04/24/06)
EH&S Helps Spread the Word About New California Law (04/24/06)
Kudos: Charles Weissmann Honored by Biotechnology Study Center; Bruce Beutler Wins Coley Award (04/24/06)
Simple Tools for Complex Problems (04/10/06)
Enzyme Crystal Structure Reveals "Unexpected" Genome Repair Functions (04/10/06)
Snapshot: Jesse Stumpp (04/10/06)
Five Kellogg School Students Win NSF Fellowships (04/10/06)
Free Range Problem-Solving (04/03/06)
Sparking an Interest in Science (04/03/06)
Snapshot: Pete Herold (04/03/06)

 

MARCH

New Class of Enzyme Inhibitors Blocks Replication of SARS Virus (03/27/06)
"Accelerated Evolution" Converts RNA Enzyme to DNA Enzyme In Vitro (03/27/06)
Kudos: Bloom Appointed to President's Council on Bioethics, Rosen Joins NIH Strategic Planning Group, Leconte and Richter Win Shelton Prizes for Graduate Studies (03/27/06)
Minor Mutations in Avian Flu Virus Increase Chances of Human Infection (03/20/06)
Newly Discovered Small Molecules "Superactivate" Botox (03/20/06)
Four Institutions Announce Stem Cell Research Alliance (03/20/06)
Novel Method Reveals How Menthol Creates Cold Sensations (03/13/06)
New Service Offers Molecular Models a.k.a. "Thinking Tools" (03/13/06)
The Accidental Author or the Price of Popularity (03/13/06)
View from a Zeppelin: Interview with George Koob (03/06/06)
The Bright Side of a Virus (03/06/06)
Cartoonist Draws on Humor and Insight (03/06/06)

FEBRUARY

A Passion for Science (02/27/06)
New Research Gives Scientists Powerful Tool For Drug Discovery (02/27/06)
Snapshot: Marisela Chevez (02/27/06)
New Study Shows Antibody-Interleukin Complexes Stimulate Immune Responses (02/27/06)
Steve Mayfield Promoted to Full Professor (02/27/06)
Bacillus anthracis: One Bad Bug (02/20/06)
IBM and Scripps Research to Collaborate on Pandemic Research (02/20/06)
Study Reveals Mechanism for Maintaining Circadian Rhythms in Mammals (02/20/06)
Scientists Re-engineer a Well-Known Antibiotic to Counter Drug Resistance (02/13/06)
High Resolution "Snapshots" Detail Dynamics of a Cocaine Antibody (02/13/06)
Everything You Always Wanted to Know About Bleach But Were Afraid to Ask (02/13/06)
Protein Found to Control Tumor Growth in Certain Breast Cancers (02/06/06)
Finger Exercises (02/06/06)
Scripps Florida Launches Volunteer Group (02/06/06)

JANUARY

Revealing the Cell Cycle's Secrets (01/30/06)
New Technologies, New Collaborations (01/30/06)
Kudos: Norman Klinman Receives Excellence in Mentoring Award; Romer Foundation honors Harry Orf (01/30/06)
Scripps Surfing Makes a Splash (01/30/06)
Study Reveals Unusual Structure of Cellular Transport Nanocage (01/23/06)
Scripps Florida Opens Its Cutting-Edge Screening Technology to Florida Scientists (01/23/06)
Snapshot: Graham Johnson (01/23/06)
Sneaking into DNA (01/23/06)
New Technology Effectively Gauges Specificity of Influenza Strains, Including 1918 Spanish Flu (01/16/06)
Scientists Describe Cellular Structure that Plays Critical Role in Drug Resistance (01/16/06)
Slideshow: New Space in the New Year (01/16/06)