Beierle, John M.

Peptide Derivatives in New Modes of Molecular Recognition

Advisor: Reza Ghadiri, Professor, Department of Chemistry

Brenzovich, William E. Jr.

Progress Towards the Total Synthesis and Structural Assignment of Amphidinolide N and Caribenolide I

Advisor: K.C. Nicolaou, Professor and Chair, Department of Chemistry

Brustad, Eric M.

Applications of an Expanded Genetic Code

Advisor: Peter Schultz, Professor, Department of Chemistry

Chappie, Joshua

Defining the Mechanisms and Regulation of Dynamin's GTPase Activities

Co-Advisors:
Ronald Milligan, Associate Professor, Department of Cell Biology
Sandra Schmid, Professor and Chair, Department of Cell Biology

Chen, Jason Shih-Hao

Part I. Chemistry and Biology of Uncialamycin
Part II. Total Synthesis of Aspidophytine

Advisor: K.C. Nicolaou, Professor and Chair, Department of Chemistry

Clark, Julie Hsu

Synthetic and Endogenous Small Molecules that Regulate Stem Cell Fate

Advisor: Sheng Ding, Associate Professor, Department of Chemistry

Clark, Ryan C.

I. An Asymmetric Variant of the 1-Azadiene Diels-Alder Reaction,
II total Synthesis, Sterochemical Reassignment and Absolute Configuration of Chlorofusin

Advisor: Dale Boger, Professor, Department of Chemistry

Dale, Trevor James

Photophysical Probes for Nerve Agent Sensing and the Study of Molecular Encapsulation

Advisor: Julius Rebek, Jr., Professor and Director, The Skaggs Institute for Chemical Biology

DeMartino, Jessica K.

Synthesis and Evaluation of Inhibitors of Glycinamide Ribonucleotide Transformylase and Fatty Acid Amide Hydrolase

Advisor: Dale Boger, Professor, Department of Chemistry

DeMartino, Michael P.

The Design and Development of Oxidative Enolate Heterocoupling and Application Toward the Total Synthesis of the Taiwankadsurins

Advisor: Phil Baran, Professor, Department of Chemistry

Frederick, Michael Oliver

Synthesis of Polyether Natural Products:
Part 1. Total Synthesis of Azaspiracids-1 and -2,
Part 2. Synthesis of the G-O Domain of Maitotoxin

Advisor: K.C. Nicolaou, Professor and Chair, Department of Chemistry

Giri, Ramesh

Chelation-Assisted Palladium-Catalyzed Activation of C-H Bonds: A New Avenue for Carbon-Heteroatom and Carbon-Carbon Bond Formation

Advisor: Jinquan Yu, Professor, Department of Chemistry

Gordley, Russell Morrison

Programmable Zinc Finger-Recombinases for Targeted Genome Editing

Advisor: Carlos Barbas III, Professor, Department of Chemistry

Guerrero, Carlos Ariel

Enantiospecific Syntheses of Stephacidin and Cortistatin Alkaloids

Advisor: Phil Baran, Professor, Department of Chemistry

Kazmierczak, Piotr

Molecules of Mechanotransduction. Cadherin 23 and Protocadherin 15 Interact to form Tip-link Filaments.

Advisor: Ulrich Mueller, Professor, Department of Cell Biology

Komori, Heather Kiyomi

Application of a Soluble Vγ3Vδ1 T Cell Receptor Towards Understanding Dendritic Epidermal T Cell Activation

Advisor: Wendy Havran, Professor, Department of Immunology and Microbial Science

Koudelka, Kristopher J.

Elucidation of Mammalian Binding and Entry of Cowpea Mosaic Virus Via Surface Vimentin; Implications for Nanotechnology and Virus Evolution

Advisor: Marianne Manchester, Professor, Department of Cell Biology

Lander, Gabe

Structural Architecture of Bacteriophage Described via Streamlined Cryo-Electron Microscopy

Co-Advisors:
Bridget Carragher, Associate Professor, Department of Cell Biology
John Johnson, Professor, Department of Molecular Biology

Lee, Joon Youb

Factors Regulating T-Cell Proliferation in Chronically Immunodeficient Hosts

Advisor: Charles Surh, Professor, Department of Immunology and Microbial Science

Lee, Sang Yeul

Chlorofusin: Total Synthesis, Stereochemical Reassignment, Determination of Absolute Configuration, and the Synthesis of Seven Chromophore Analogs

Advisor: Dale Boger, Professor, Department of Chemistry

Lincoln, Tracey

Self-Sustained Replication of an RNA Enzyme

Advisor: Gerald Joyce, Professor, Department of Department of Molecular Biology and Chemistry

Marrinucci, Dena Christine

The Clinical and Biological Significance of Circulating Tumor Cells

Advisor:
Peter Kuhn, Associate Professor, Department of Cell Biology

Michino, Mayako

Structure Prediction of Class A GPCRs

Co-Advisors:
Charles L. Brooks III
Raymond Stevens, Professor, Department of Molecular Biology

Niessen, Sherry L.

Characterization of a Role for the Serine Hydrolase Enzyme KIAA1363 in Cancer Biology Using Functional Proteomics and Metabolomics

Advisor: Benjamin Cravatt, Professor and Chair, Department of Chemical Physiology

Pragani, Rajan

Studies Toward the Synthesis of Durhamycins A and B and Ziracin

Advisor:
William Roush, Professor, Department of Chemistry

Pratt, Benjamin Anthony

The Design and Synthesis of Highly Potent Epothilone B Analogues and Progress Toward the Total Synthesis of Sinularia Natural Products

Advisor: K.C. Nicolaou, Professor and Chair, Department of Chemistry

Radakovits, Randor R.

Investigating the role of β1 integrins and glial fibers in the survival of radial glial cells

Advisor: Ulrich Mueller, Professor, Department of Cell Biology

Raushel, Jessica

Part I. Sulfonyl Azides: Copper-Mediated Synthesis and Applications
Part II. Acetylcholinesterase in Situ Clock Chemistry Screening

Advisor:
K. Barry Sharpless, Professor, Department of Chemistry

Scherer, Erin M.

Antibody Recognition of a Protein Epitope Close to a Membrane: A Novel Solution

Advisor: Dennis Burton, Professor, Department of Immunology and Microbial Science

Schnermann, Martin John

I. Total Synthesis of Piericidin A1 and B1 and Key Analogues,
II. Studies Towards the Total Synthesis of Vinblastine and Velbanamine Aryl Analogues

Advisor: Dale Boger, Professor, Department of Chemistry

Shenvi, Ryan A.

Pure and Applied Science in the Chemical Synthesis of Marine Alkaloids Chartelline C and Cortistatin A

Advisor: Phil Baran, Professor, Department of Chemistry

Siegel, Sarah J.

Structure and Energetics of Amyloid

Advisor: Jeffrey Kelly, Professor and Chair, Department of Molecular and Experimental Medicine

Slown, Corin D.

Studies Toward Understanding the Mechanism of Bleomycin: Total Synthesis of 15N-labeled Bleomycin

Advisor: Dale Boger, Professor, Department of Chemistry

Thielges, Megan C.

Novel Approaches to the Study of Protein Dynamics

Advisor:
Floyd Romesberg, Associate Professor, Department of Chemistry

Voytek, Sarah B.

Continuous In Vitro Evolution of Competing Ligase Ribozymes

Advisor: Gerald Joyce, Professor, Department of Department of Molecular Biology and Chemistry

Yonemoto, Isaac

Theory, Methods and Investigations in Amyloid Dynamics

Advisor: Jeffrey Kelly, Professor and Chair, Department of Molecular and Experimental Medicine