This ribbon diagram represents a single NMR structure of the Hif-1a:TAZ1 complex that the team solved (TAZ1 is the zinc-binding element of CBP). The amino terminus of the rust-colored Hif-1a and the carboxy and amino termini of the blue TAZ1 are labeled. The zinc ions are represented as white spheres, and the side chains of the cysteine and histidine ligands are shown in yellow and blue, respectively.