Danuta Balicki, M.D.

Gene Transfer Mediated by Histone H2A

Advisor: Ernest Beutler, professor and chairman,
Department of Molecular and Experimental Medicine

Christopher N. C. Boddy

Synthesis of the Diaryl Ethers of Vancomycin: Controlling Sterogenic Axes

Advisor: K. C. Nicolaou, professor and chairman,
Department of Chemistry

Dennis T.Y. Bong

Part I. Mechanistic Insights into Nodaviral Transfection
Part II. Directing Peptide Self-Assembly

Advisor: M. Reza Ghadiri, professor, Department of Chemistry and Molecular Biology

Steven L. Castle

Total Synthesis of the Vancomycin Aglycon and Related Compounds

Advisor: Dale L. Boger, professor,
Department of Chemistry

Phyllis Frosst

Localization and Function of Tpr, a Component of the Nuclear Pore Complex

Advisor: Larry Gerace, professor,
Department of Cell Biology

Joel Goldberg

Part I. Solvolysis Regioselectivity and X-Ra Structure of the Duocarmycin SA Alkylation Subunit
Part II. Solution Phase Synthesis of Compound Libraries Targeting the Erythropoietin Receptor
Part III. Identification of a New Class of Angiogenesis Inhibitors which Function by Blocking the Interaction of Proteinase MMP2 and Integrin avb3

Advisor: Dale L. Boger, professor,
Department of Chemistry

David J. Hosfield

Structural Studies of Two Archetypical DNA Repair Enzymes and their DNA Complexes

Advisor: John A. Tainer, professor,
Department of Molecular Biology

Kinya Hotta

Structural Insight into a Decarboxylase Antibody

Advisor:Ian A. Wilson, professor,
Department of Molecular Biology

Kathryn M. Koeller

Chemical and Enzymatic Synthesis of Oligovalent Carbohydrate, Glycopeptide, and Aminoglycoside Recognition Elements: Multivalency in Natural and Synthetic Glycoconjugate Structure

Advisor: Chi-Huey Wong, professor,
Department of Chemistry

Nicole Kresge

Sex at the Molecular Level: The Crystal Structures of Abalone Fertilization Proteins

Advisor:C. David Stout, associate professor,
Department of Molecular Biology

Ryan S. Littlefield

Regulation of Thin Filament Length in Striated Muscle

Advisor: Velia M. Fowler, professor,
Department of Cell Biology

Satchidananda Panda

TEJ Defines a Role for Poly (ADP-Ribosyl)ation in Establishing Period Length of the Arabidopsis Circadian Oscillator

Advisor: Steve A. Kay, professor,
Department of Cell Biology

Matthew P. Patricelli

Biochemical and Physiological Investigations of Fatty Acid Amide Hydrolase

Advisor: Benjamin F. Cravatt, assistant professor,
Departments of Cell Biology and Chemistry

H. Michael Petrassi

Design and Synthesis of Inhibitors of Transthyretin Amyloid Fibril Formation

Advisor: Jeffery W. Kelly, professor,
Department of Chemistry

Christopher D. Putnam

Structural Basis for Four Pardigmatic Defenses Preventing DNA Damage in the Cell

Advisor: John A. Tainer, professor,
Department of Molecular Biology

Erica Ollmann Saphire

Crystal Structure of an Intact Human IgG: Implications for HIV-1 Neutralization and Effector Function

Advisor: Ian A. Wilson, professor,
Department of Molecular Biology

Allen A. Thomas

I. Aminohydroxylation of Unsaturated Phosphonates: A Template for Molecular Diversity
II. Rapid Discoveries in 0smium (VIII) Catalysis Using Automation and Mass Spectrometry

Advisor: K. Barry Sharpless, professor,
Department of Chemistry

Jonathan D. Toker

Discovery and Exploration of an Antibody- Catalyzed Asymmetric 1, 3-Dipolar

Advisor: Kim D. Janda, professor,
Departments of Chemistry and Molecular Biology

Vickie Tsui

NMR Restraints and Solvent Models in Molecular Dynamics Simulations: Effects on Biomolecular Structure and Intermolecular Interactions

Advisor: David A. Case, professor,
Department of Molecular Biology

Jacques T. Weissman

Regulation of Mammalian Cargo ER Export

Advisor: William E. Balch, professor,
Department of Cell Biology

Yohei Yokobayashi

Catalytic and Autocatalytic Peptide Networks

Advisor: M. Reza Ghadiri, professor,
Department of Chemistry and Molecular Biology