2024 SoCal Genome Stability Symposium

We are excited to announce the eighth annual SoCal Genome Stability Symposium. The Symposium is coordinated in partnership by Scripps Research, City of Hope, University of Southern California and University of California, Irvine.

The SoCal Genome Stability Symposium offers postdoctoral associates and graduate students the opportunity to present their current research and to connect with their peers from other laboratories.

The symposium comprises morning and afternoon talks by postdoctoral associates and graduate students, primarily on unpublished work. A poster session will culminate in the awarding of cash prizes and a vendor show will offer attendees the opportunity to discuss recent innovations with representatives from leading biotech companies.

Free attendance for academic participants, register by November 30th, 2024

Please find more information in the Event Details listed below.

Click here for the program schedule.

If you are interested in sponsoring the event, please contact Xiaohua Wu at xiaohwu@scripps.edu.

EVENT ORGANIZERS

Xiaohua Wu, PhD, Scripps Research
Jeremy Stark, PhD, City of Hope
Irene Chiolo, PhD, University of Southern California
Rémi Buisson, PhD, University of California, Irvine

Date:
Friday, December 13, 2024

Time:
9:00 a.m. - 6:30 p.m.

Location:
The Scripps Research Institute
Scripps Research Auditorium
10620 John Jay Hopkins Dr, San Diego, CA 92121

Meeting Program

9:00 - 9:10 am	Welcome Remarks (Xiaohua Wu, Scripps Research)
9:10 - 10:25 am	Talk Session 1: DNA Repair and Genome Stability (Session chair: Rémi Buisson, UCI) 9:10 - 9:25 am: Tony Fernandez, Ph.D. (Binghui Shen’s lab, City of Hope) - DNA2 and MSH2 Activities Collectively Remove Chemically Stabilized G4 for Efficient Telomere Replication 9:25 - 9:40 am: Pedro Ortega, Ph.D. (Rémi Buisson’s lab, UCI) - Mechanism Of Fork Breakage During Replication Catastrophe 9:40 - 9:55 am: Christine Joyce (Chris Richardson’s lab, UCSB) - The FANCD2-FANCI heterodimer regulates DNA repair activity and cell cycle progression in response to double strand breaks 9:55 - 10:10 am: Ting Zhao (Yinsheng Wang’s lab, UCR) - Identification and Functional Characterizations of N2-Alkyl-Dg-Binding Proteins 10:10 - 10:25 am: Nadejda Butova (Irene Chiolo’s lab, USC) - Ulp1: a clock for heterochromatin repair
10:30 – 11:00 am	Poster “Lightning Talks”
11:10 – 12:45 pm	Poster Session
12:45 – 1:30 pm	Lunch
1:30 – 2:45 pm	Talk Session 2: Genomics and Gene Editing (Session Chair: Shannon Miller, Scripps Research) 1:30 – 1:45 pm: Peter Chovanec, Ph.D. (Yi Yin’s lab, UCLA) - Towards a single-cell atlas of spontaneous genome instability events in vivo 1:45 – 2:00 pm: Xiaoyu (Lydia) Chen (Audrone Lapinaite’s lab, UCI) - From Structure to Function: How Deaminase Domain Dimerization and Cas9 Interactions Drive Base Editing Efficiency in ABE8e 2:00 – 2:15 pm: Mallory Evanoff, Ph.D. (Alexis Komor’s lab, UCSD) - Directed Evolution Reversion Analysis Produces Minimally Mutated Adenine Base Editor Variants with Improved Efficiency and Precision 2:15 – 2:30 pm: Seanmory Sothy (Linlin Zhao’s lab, UCR) - Mass Spectrometry-Based Quantification of Base Excision Repair Intermediates 2:30 – 2:45 pm: Shuvro P. Nandi, Ph.D. (Ludmil B. Alexandrov’s lab, UCSD) - UDSeq: A Universal Duplex Sequencing for Precise Genome-Wide Identification of Somatic Mutation
2:45 – 3:15 pm	Coffee Break
3:15 – 4:30 pm	Talk Session 3: Chromosomal Rearrangement and Cancer Treatment (Session Chair: Irene Chiolo, USC) 3:15 – 3:30 pm: Sameer Shah, Ph.D. (Xiaohua Wu’s lab, Scripps Research) - 53BP1deficiency Leads to Hyperrecombination Using Break-Induced Replication (BIR) 3:30 – 3:45 pm: Kaela Makins (Jeremy Stark’s lab, City of Hope) - Defining The Interplay Between DNA-Pkcs and RIF1-53BP1 During Chromosomal Break Repair 3:45 – 4:00 pm: Megha Raghunathan (Svasti Haricharan’s lab, SDSU) - Mismatch Repair Gene-Specific Effects on Breast Tumor Formation, Progression and Genomic Instability 4:00 – 4:15 pm: Shuangshuang Xie, Ph.D. (Dan Semlow’s lab, Caltech) - The Microbiome-Derived Colibactin Genotoxin Activates cGAS-STING-Dependent Pro-Inflammatory Signaling 4:15 – 4:30 pm: Ya Allen Cui, Ph.D. (Wei Li’s lab, UCI) - Tandem Repeat Variation in Human Health and Diseases
4:30 – 4:45 pm	Poster Awards Announcement/Closing Remarks
5:00 – 6:30 pm	Dinner (Meet Professors: Career Development)
6:30 pm	End of the Symposium

Poster Session Instruction, 8^th SoCal Genome stability symposium

10:30 - 11:00 am

Poster "Lightning Talks"

Each presenter will give a one-minute presentation.

11:10 - 12:30 pm

Poster Session

Poster Awards:

First Prize: One $150
Second Prize: Two $100
Third Prize: Three $50

Poster Guidelines:

Please indicate whether you would like to participate in the poster session when you register. Note: the registration deadline for posters is November 30th. Submit your poster title together with your registration.
A board number will be provided for each poster after registration and can be found on the poster boards.
Board size: 60''w x 36''h
Poster pins will be provided

Meet Professors

12:30 - 1:30 pm - Lunch (Meet Professors: Career Development 1)

5:15 - 6:30 pm - Dinner (Meet Professors: Career Development 2)

We thank the following sponsors for supporting the SoCal Genome Stability Symposium

For more information or sponsorship opportunities, please contact Xiaohua Wu at xiaowu@scripps.edu or (858) 784-7910.

Postdoctoral positions are currently available in the labs listed below. Click the position Ad link to see job details. If you have questions, please directly contact the PIs of the labs you are interested.

Event Location

Scripps Research Auditorium
10620 John Jay Hopkins Drive
San Diego, CA 92121

Campus map

Conference room map

Karen Hughes, Administrative Manager
(858) 784-7917 | khughes@scripps.edu