The Friedlander Laboratory Department of Cell Biology

Michael I. Dorrell, Edith Aguilar, Christoph Weber, Martin Friedlander. IOVS The Scripps Research Institute, La Jolla, CA Microarray Home      Statistical Analyses      Gene Search

Cluster 4

Genes with a constant decrease in expression (shallow slope)

Clusters 4, 7, and 8 represent genes expressed during post-natal mouse retina development, whose expression is high at birth and then generally decreases throughout post-natal development. The final stages of retina neural development continue through the first week after birth, after which final maturation of the retina takes place coinciding with visual acuity at post-natal day 14. Although many developmental events are occurring simultaneously and caution should be taken when predicting gene functions from expression data alone, these genes have a higher likelihood of being involved in neural development. This includes genes required for the proliferation, migration, differentiation and maturation of neurons and neuronal synapses. Cluster 4 genes generally have smaller, more consistent overall decreases in expression.

Genes normalized chip to chip and per gene
"po-adult, triplicate"

Common Name	P0	P4	P8	P10	P12	P14	P21	Adult	Genbank	Affy ID#	Keywords	Product	Function