Mouse Retinal Gene Expression

The Friedlander Laboratory
Department of Cell Biology

Michael I. Dorrell, Edith Aguilar, Christoph Weber, Martin Friedlander. IOVS
The Scripps Research Institute, La Jolla, CA

Microarray Home Statistical Analyses Gene Search

Cluster 8

Genes whose expression decreases throughout the timeseries (steep slope)

Clusters 4, 7, and 8 represent genes expressed during post-natal mouse retina development, whose expression is high at birth and then generally decreases throughout post-natal development. The final stages of retina neural development continue through the first week after birth, after which final maturation of the retina takes place coinciding with visual acuity at post-natal day 14. Although many developmental events are occurring simultaneously and caution should be taken when predicting gene functions from expression data alone, these genes have a higher likelihood of being involved in neural development. This includes genes required for the proliferation, migration, differentiation and maturation of neurons and neuronal synapses. Cluster 8 genes generally have high expression levels at birth that dramatically decrease throughout the first 2 weeks after birth to the extent where many of these genes are no longer expressed after P14.

Per gene and chip to chip normalization
"po-adult, triplicate"

Common Name P0 P4 P8 P10 P12 P14 P21 Adult Genbank Affy ID# Keywords Product Function
Cmkar4 10.119 3.464 1.793 1.168 0.568 0.568 0.676 0.464 Z80112 102794_at CXC chemokine receptor 4; CXCR-4; lcr-1 gene CXCR-4 receptor for chemokine SDF-1
2810047L02Rik 25.587 5.788 1.72 0.705 0.089 1.27 0.862 0.102 AW212532 104423_at EST
Np95 12.01 4.486 1.539 0.642 0.19 0.598 0.432 0.371 D87908 99564_at nuclear protein Np95 nuclear protein np95
Crabp2 15.982 7.616 2.847 1.706 0.134 0.855 0.579 0.45 M35523 100127_at cellular retinoic acid-binding protein
Pttg1 16.256 10.385 2.692 1.276 0.156 0.42 0.761 0.148 AF069051 101027_s_at pituitary tumor transforming gene protein
AA410048 17.777 5.922 2.603 1.199 0.147 0.808 0.871 0.224 AW259499 103203_f_at EST
Trip13 5.992 5.126 2.148 1.089 0.089 1.339 1.269 0.072 AI852645 101372_at EST
Cdc25c 22.347 13.329 4.594 0.197 0.18 1.871 0.116 0.162 U15562 102935_at CDC25
Kif4 16.773 7.416 2.069 0.188 0.171 1.44 0.45 0.069 D12646 104644_at KIF4; kif4; kinesin family; microtubule-dependent ATPase activity; microtubule-associated motor protein; tubulin binding KIF4
2600009M07Rik 7.182 3.647 1.756 0.233 0.109 0.647 0.234 0.121 AW060657 98552_at EST RIKEN cDNA 2600009M07
Igf2bp1 12.388 6.038 2.538 1.056 0.074 0.849 0.109 0.154 AF061569 102627_at coding region determinant binding protein putative c-myc mRNA binding protein
Brca1 9.421 4.025 2.185 1.374 0.187 1.243 0.169 0.121 U32446 102976_at breast/ovarian cancer susceptibility protein homolog
Gna12 4.726 1.546 1.993 0.991 0.209 0.846 0.196 0.201 M63659 97227_at G-alpha-12 protein G-alpha-12 protein
2810417H13Rik 19.324 10.543 2.622 0.962 0.101 0.563 1 0.954 AI122538 100116_at EST
Chek1 10.052 5.486 2.552 1.991 0.145 1.154 1.5 1.763 AF016583 103064_at Chk1
Ccnd1 7.598 5.517 1.464 0.888 0.064 0.883 0.52 1.119 M64403 94231_at cyclin-like protein cyclin-like protein
Zac1 21.082 3.136 3.689 2.195 0.179 1.303 1.509 1.509 X95504 92502_at zinc finger protein zinc finger protein
Epha3 5.083 1.628 2.33 1.203 0.215 1.161 0.921 0.958 M68513 95298_at receptor tyrosine kinase receptor tyrosine kinase
Exo1 10.13 3.206 0.247 1.245 0.092 0.754 1.722 0.245 AJ238213 92244_at Exo1 gene; exonuclease 1 homologue exonuclease 1 homologue putative mismatch repair protein
C80208 60.734 37.082 0.244 7.611 0.137 0.139 3.217 0.125 AI428843 97095_at EST
Stk6 8.558 4.473 1.808 1.045 0.964 0.846 1.06 0.194 U80932 92639_at serine/threonine kinase Ayk1
Fin16 12.782 6.04 1.973 1.146 0.94 0.657 0.898 0.106 U42385 97421_at fibroblast growth factor inducible 16
Cdc20 15.378 6.531 2.237 1.058 0.833 0.816 0.683 0.098 AW061324 96319_at EST
Mcmd5 6.855 4.677 1.29 0.695 0.837 0.68 0.647 0.11 D26090 100156_at mCDC46; CDC46; mCDC46 protein; DNA replication mCDC46 protein possibly involved in DNA replication
Csrp2 6.599 4.873 2.112 0.806 0.4 0.437 0.347 0.045 D88792 93550_at double LIM protein-1 double LIM protein-1
2310035M22Rik 14.773 7.772 2.378 1.444 0.53 0.384 0.53 0.107 AI851230 99149_at EST
EST 9.64 4.949 2.264 1.914 0.976 1.51 0.593 0.37 AI843655 103071_at EST
Mns1 8.518 3.955 1.324 1.032 0.611 0.837 0.518 0.229 D14849 103468_at MNS1; meiosis-specific nuclear structural protein 1 meiosis-specific nuclear structural protein 1
2700084L22Rik 12.643 8.67 2.964 1.324 1.548 1.071 0.409 0.094 AA989957 100955_at EST
2610200G18Rik 7.766 7.311 2.748 1.841 1.637 0.812 0.431 0.102 AI840035 104229_at EST
EST 9.872 3.472 2.701 1.347 1.38 0.832 0.324 0.106 AI851599 92180_at EST
Idb1 10.366 5.048 2.926 2.969 2.5 2.248 0.848 0.146 M31885 100050_at helix-loop-helix DNA binding protein regulator; helix-loop-helix protein; regulatory protein
Bid 3.732 2.914 2.065 1.664 0.909 1.109 0.383 0.112 U75506 98433_at BID apoptotic death agonist
Lmyc1; Lmyc-1 5.266 4.354 2.622 1.988 0.645 0.347 0.024 0.026 X13945 102235_at l-myc oncogene; myc oncogene L-myc protein
2810052M02Rik 4.569 4.222 2.613 1.994 1.286 0.395 0.08 0.056 AI852196 95150_at EST
Dcx 6.485 5.877 2.748 2.234 1.315 0.952 0.074 0.139 AB011678 102307_at doublecortin doublecortin
Cd1d1 4.859 4.286 2.531 1.907 0.723 0.869 0.164 0.297 M63695 103422_at CD1 antigen; CD1.1 antigen; cell surface glycoprotein CD1.1
Rbl1 10.882 4.565 1.932 1.587 0.977 1.181 0.169 0.183 U27177 104476_at p107
Rrm1 8.055 4.593 2.2 1.599 0.635 0.808 0.136 0.132 K02927 100612_at ribonucleotide reductase ribonucleotide reductase M1
Cks1 7.401 4.688 2.378 2.122 1.069 0.973 0.146 0.082 AB025409 97468_at sid1334p sid1334p
Myb 17.378 4.155 2.594 1.706 0.441 0.345 0.108 0.039 M12848 92644_s_at myb proto-oncogene; proto-oncogene myb protein
Fabp7; Blbp; B-FABP 2.427 5.234 2.985 2.091 0.536 0.452 0.066 0.021 U04827 98967_at brain fatty acid-binding protein
Cd24a 3.302 3.195 2 1.43 0.469 0.412 0.212 0.171 M58661 100600_at heat-stable antigen M1/69-J11d heat-stable antigen
H19; AI747191 4.724 3.488 3.032 1.623 0.443 0.223 0.113 0.133 X58196 93028_at embryogenesis; H19 gene H19 fetal liver mRNA
Bub1 45.199 25.305 5.957 1.12 0.473 0.142 0.069 0.096 AF002823 104097_at mitotic checkpoint protein kinase
Sox11 6.755 5.652 1.693 1.112 0.376 0.284 0.151 0.269 AW107922 93669_f_at EST
Knsl1 34.728 16.296 2.982 1.615 0.56 0.15 0.115 0.057 AJ223293 99541_at eg5 gene; kinesin-related; mitotic motor protein kinesin-related mitotic motor protein essential for bipolar spindle
Mki67 57.132 23.44 5.192 1.5 0.323 0.027 0.099 0.058 X82786 99457_at Ki-67 gene
Cdc45l 7.631 2.968 1.844 0.854 0.805 0.175 0.231 0.204 AF098068 102403_at CDC45-related protein putative DNA replication initiator protein
Dll1 11.822 6.199 3.747 1.635 0.837 0.137 0.138 0.107 X80903 92931_at delta-like 1 gene DELTA-like 1
Mapk7 5.412 5.48 2.606 2.297 0.579 0.075 0.066 0.1 AB019373 99000_at ERK5 ERK5
Cyp1b1 5.207 2.52 2.259 2.241 0.991 0.103 0.125 0.149 X78445 99979_at CYP1b gene; Cytochrome P450 cytochrome P450EF B1
Tpm3 7.779 6.182 4.185 5.7 4.453 0.199 0.155 0.172 X53753 93265_at tropomyosin "tropomyosin 3, gamma"
Casp6 4.501 5.953 3.812 2.47 0.15 0.171 0.666 0.048 Y13087 94458_at caspase-6; cysteine protease caspase-6 cysteine protease
2810052M02Rik 3.955 3.07 2.421 2.005 0.674 0.24 1.143 0.168 AW061307 95152_g_at EST
Sox3 4.415 2.23 2.454 1.81 1.137 0.602 1.147 0.119 AA866668 103301_i_at EST
Prim2 5.008 2.93 2.147 1.808 0.671 1.268 0.991 0.07 D13545 95549_at primase large subunit; PRIM2 primase large subunit
Mcmd 19.063 6.257 1.198 1.509 1.719 0.117 1.647 1.146 X62154 100062_at p1 protein P1.m protein
EST 8.455 3.19 1.767 1.996 1.595 0.162 0.913 1.611 T25639 101203_r_at EST
Lamb2; Lams; Lamb-2 5.114 3.346 1.556 0.945 0.781 0.117 0.756 2.33 U43541 101359_at laminin beta 2
Tera-pending 5.831 1.832 2.546 1.754 0.558 0.108 0.632 0.535 U64033 103385_at Tera
G7e 16.843 5.698 2.445 0.765 0.648 0.273 0.616 1.148 U69488 104333_at viral envelope like protein
5730403J10Rik 30.453 10.217 1.825 0.917 0.815 0.083 0.338 0.555 AI049398 102354_at EST
2310021G01Rik 21.101 7.324 2.616 1.189 0.752 0.094 0.494 1.011 AI606257 95063_at EST
Zfp36l1 7.004 3.858 1.687 1.356 0.959 0.675 0.671 0.919 M58566 93324_at TIS11 gene "zinc finger protein 36, C3H type-like 1" TIS11 primary response gene
Birc5 35.835 15.646 4.746 1.08 0.142 0.181 0.778 0.492 AB013819 101521_at TIAP; Tiap TIAP
Tacc3 26.143 10.434 4.294 0.696 0.109 0.061 0.184 0.364 AW209238 97238_at EST
Fgf3; Fgf-3; Int-2; Int-P 12.307 3.128 3.42 1.187 0.329 0.186 0.254 1.402 Y00848 92957_at int-2 gene; oncogene int-2
Cdc25c 12.551 7.428 3.301 0.19 1.566 0.176 0.164 1.673 L16926 102934_s_at cdc25 phosphatase cdc25 phosphatase
Hells 26.311 8.368 2.255 0.159 1.217 0.184 0.072 3.865 U25691 93228_at lymphocyte specific helicase
Mad3 12.685 8.268 3.298 0.632 1.235 0.521 0.123 1.327 U32394 103237_at Max-interacting transcriptional repressor
TK 5.016 3.174 1.47 0.881 1.064 0.66 0.37 0.907 X60980 96081_at regulatory sequences; thymidine kinase; TK gene thymidine kinase
EST 19.139 5.828 2.169 0.731 0.49 0.667 0.043 0.547 AW213883 95753_at EST
Plk-ps1 5.431 3.669 1.47 1.022 1.097 0.926 0.178 1.506 U73170 101350_g_at
Notch1 3.934 4.216 2.576 1.355 0.458 0.21 0.058 0.393 Z11886 97497_at notch-1 notch-1
6230425C21Rik 6.501 4.203 2.26 1.811 1.11 0.672 0.053 0.565 AA881438 97967_at EST
Fzd2 6.435 3.604 3.015 2.366 1.326 0.104 0.052 0.902 AW123618 93681_at EST
Smoh 5.966 2.859 2.656 1.858 1.144 0.106 0.098 1.015 AF089721 96812_at
EST 2.926 2.748 1.44 1.071 0.433 0.549 0.358 0.586 AF109906 92656_at RD; Bf; C2; G9A; NG22; HSP70; HSC70t; smRNP; G7A
EST 36.632 16.182 3.616 1.107 0.095 0.132 0.095 0.764 AI591702 96168_at EST
EST 26.167 14.983 2.816 1.188 0.084 1.107 0.038 0.462 AI595322 93441_at EST
1110037A17Rik 12.763 6.935 2.089 0.788 0.147 0.439 0.054 0.352 AW123269 96784_at EST
Tnfip6 7.553 6.216 3.937 2.822 0.118 0.553 0.107 1.236 U83903 98474_r_at TNF-stimulated gene 6 protein
Crip 3.219 5.055 2.066 2.014 0.095 0.075 0.068 0.489 M13018 94061_at cysteine-rich intestinal protein cysteine rich intestinal protein
Pole2 25.152 15.921 2.242 0.089 0.16 0.185 1.345 2.391 AF036898 101920_at DNA polymerase epsilon small subunit
Rrm2 20.406 4.463 2.411 0.132 0.621 0.644 0.873 0.967 M14223 102001_at reductase; ribonucleotide reductase ribonucleotide reductase M2
E2f1 69.569 31.429 13.126 0.291 0.173 0.162 1.653 0.197 L21973 102963_at E2F transcription factor 1
Mybl2 9.256 4.219 2.201 0.185 0.202 0.317 1.827 0.316 X70472 100023_at B-myb gene; proto-oncogene myeloblastosis oncogene-like 2
2410006H10Rik 51.343 53.968 1.864 0.148 3.085 2.474 2.962 0.126 AI317217 94971_at EST
Pros1 4.19 2.789 1.985 0.196 0.946 0.913 1.116 0.228 L27439 104728_at protein S protein S
Mcmd7 6.71 2.845 2.001 1.433 0.67 0.618 0.54 0.445 D26091 93356_at mCDC47; minichromosome maintenance (Mcm) protein; mouse protein CDC47 mCDC47 possibly involved in DNA replication
Ezh2 6.121 3.056 1.859 1.535 0.782 0.696 0.478 0.491 U52951 99917_at vertebrate polycomb-group gene mEnx-1
Stk18 8.258 3.619 1.686 1.405 0.799 0.755 0.611 0.464 L29480 98996_at serine/threonine kinase serine/threonine kinase
Tead2 7.125 3.723 2.261 1.3 0.405 0.509 0.433 0.468 Y10026 96940_at TEF1 gene; transcription factor transcription factor TEF-1
Ccnd1 8.397 3.997 1.515 0.645 0.254 0.216 0.227 0.293 AI849928 94232_at EST
Cdc2a 49.55 30.568 5.783 1.46 0.168 0.162 0.083 0.085 M38724 100128_at cell cycle protein cell cycle protein p34
Ckap2 27.322 16.635 3.829 1.167 0.183 0.168 0.13 0.105 AI121796 104322_at EST
Sox11 6.637 5.918 2.032 1.198 0.436 0.283 0.223 0.185 AF009414 101631_at SOX11
Hes6 6.118 3.852 2.151 1.347 0.56 0.457 0.362 0.282 AW048812 97334_at EST
Tyms 5.393 3.763 1.602 1.057 0.408 0.347 0.427 0.286 AU044050 93237_s_at EST
Prdx4 4.032 3.942 1.682 1.065 0.645 0.597 0.419 0.311 U96746 93495_at antioxidant enzyme AOE372
3110003A17Rik 3.624 3.818 1.519 0.878 0.621 0.626 0.376 0.377 AA833425 96135_at EST
2310046G15Rik 7.359 5.369 2.642 1.938 0.917 1.091 0.779 0.557 AW228316 94238_at EST
EST 4.665 3.523 1.717 1.005 0.723 0.756 0.663 0.453 AF109905 95654_at Hsc70t; smRNP; G7A; NG23; MutS homolog; CLCP; NG24; NG25; NG26
1110038L14Rik 12.824 10.319 2.131 0.889 0.46 0.645 0.507 0.266 AA681998 97527_at EST
EST 5 5.779 1.584 0.557 0.343 0.25 0.228 0.27 M33988 94805_f_at histone H2A.1 histone H2A.1
Top2a 276.752 104.256 23.869 0.398 0.139 0.183 0.103 0.373 U01915 99578_at DNA topoisomerase IIalpha DNA relaxing enzyme
Stk5 38.08 26.419 11.371 0.211 0.205 0.187 0.216 0.195 D21099 98469_at MMSTK1; serine/threonine kinase; STK-1; protein kinase STK-1
Ascl1 38.734 20.259 9.298 0.416 0.176 0.102 0.104 0.112 M95603 102238_at helix-loop-helix protein helix-loop-helix protein
Ttk 10.578 5.582 1.621 0.441 0.454 0.464 0.718 0.481 M86377 103201_at esk kinase esk kinase
Hmgb2 8.74 7.254 1.941 0.993 0.575 0.666 0.986 0.578 X67668 93250_r_at high mobility group 2 protein high mobility group 2 protein
Six6 8.65 7.561 1.109 0.22 0.228 0.141 0.202 0.227 AJ011787 101797_at OPTX2 gene; Optx2 protein; Six9 gene; Six9 protein Six9 protein
Ccnb2 6.629 3.231 1.166 0.478 0.476 0.393 0.385 0.485 X66032 94294_at cell cycle regulatory protein; cycB2 gene cyclin B2
Prim1 6.849 3.799 1.538 0.687 0.753 0.739 0.653 0.558 J04620 96772_at RNA polymerase; primase; primase p49 subunit primase p49 subunit
EST 13.045 6.158 1.723 0.765 0.706 0.414 0.484 0.35 AA856349 95032_at EST
Ect2 9.359 4.233 1.132 0.65 0.584 0.553 0.444 0.535 L11316 97411_at oncogene ect2 oncogene
Fgf15 258.193 47.233 0.667 0.331 0.215 0.206 0.162 0.174 AF007268 97721_at fibroblast growth factor
C79407 6.947 4.493 1.152 0.717 0.539 0.567 0.7 0.599 AI450597 103308_at EST
Calmbp1 152.561 72.419 1.067 0.145 0.276 0.195 0.205 0.249 AF062378 102632_at calmodulin-binding protein SHA1
4831429J16Rik 8.708 4.322 1.615 0.534 0.823 0.928 0.547 0.644 AW122331 97295_at EST
Atoh7 105.242 17.884 0.209 0.185 0.209 0.22 0.247 0.36 AF071223 101811_at transcription factor Math5
Kifc1 31.363 14.207 0.214 0.204 0.17 0.21 0.209 0.22 D49544 98471_f_at KifC1; KIFC1 KIFC1 kinesin-related mechanochemical ATPase
Epha2 14.136 3.307 0.458 0.258 0.182 0.219 0.747 0.243 U07634 103980_at receptor-protein tyrosine kinase
Vrk1 9.971 5.919 0.256 0.238 0.218 0.678 0.178 0.092 AF080253 97393_at serine/threonine protein kinase 51PK(L)
Foxm1 39.254 5.626 0.296 0.207 0.248 2.898 0.18 0.253 Y11245 98305_at transcription factor winged-helix transcription factor
C77459 55.207 28.48 0.443 0.634 3.272 1.09 0.201 0.188 AI510131 98489_at EST
Pdlim1 10.646 6.745 0.357 0.255 1.539 0.132 0.12 0.118 AF053367 100554_at carboxyl terminal LIM domain protein
Chaf1a 4.762 5.158 0.188 0.281 1.076 0.211 0.166 0.188 AJ132771 95527_at CAF-Ip150 gene; chromatin assembly factor-I; p150 subunit chromatin assembly factor-I p150 subunit DNA replication-dependent assembly of nucleosomes
Grb10 7.93 0.784 0.24 0.214 0.276 0.153 1.571 0.278 U18996 93691_s_at growth factor receptor binding protein Grb10
1700003K02Rik 8.637 2.46 0.265 0.144 0.191 1.194 1.618 1.287 AW213865 97364_at EST
Hoxa13 4.605 7.113 1.569 0.325 0.197 7.198 0.241 0.247 U59322 94636_at transcription factor HOXA13
Cdk2 5.847 3.938 0.127 2.556 0.162 0.102 0.197 2.192 AJ223732 94411_at CDK2 gene; cyclin dependent kinase cyclin dependent kinase
Xtrp2 5.946 3.461 0.157 3.502 0.2 2.143 0.199 2.638 AF075267 97465_at orphan transporter isoform A8

Common Name	P0	P4	P8	P10	P12	P14	P21	Adult	Genbank	Affy ID#	Keywords	Product	Function
Cmkar4	10.119	3.464	1.793	1.168	0.568	0.568	0.676	0.464	Z80112	102794_at	CXC chemokine receptor 4; CXCR-4; lcr-1 gene	CXCR-4	receptor for chemokine SDF-1
2810047L02Rik	25.587	5.788	1.72	0.705	0.089	1.27	0.862	0.102	AW212532	104423_at	EST
Np95	12.01	4.486	1.539	0.642	0.19	0.598	0.432	0.371	D87908	99564_at	nuclear protein Np95	nuclear protein np95
Crabp2	15.982	7.616	2.847	1.706	0.134	0.855	0.579	0.45	M35523	100127_at	cellular retinoic acid-binding protein
Pttg1	16.256	10.385	2.692	1.276	0.156	0.42	0.761	0.148	AF069051	101027_s_at		pituitary tumor transforming gene protein
AA410048	17.777	5.922	2.603	1.199	0.147	0.808	0.871	0.224	AW259499	103203_f_at	EST
Trip13	5.992	5.126	2.148	1.089	0.089	1.339	1.269	0.072	AI852645	101372_at	EST
Cdc25c	22.347	13.329	4.594	0.197	0.18	1.871	0.116	0.162	U15562	102935_at		CDC25
Kif4	16.773	7.416	2.069	0.188	0.171	1.44	0.45	0.069	D12646	104644_at	KIF4; kif4; kinesin family; microtubule-dependent ATPase activity; microtubule-associated motor protein; tubulin binding	KIF4
2600009M07Rik	7.182	3.647	1.756	0.233	0.109	0.647	0.234	0.121	AW060657	98552_at	EST	RIKEN cDNA 2600009M07
Igf2bp1	12.388	6.038	2.538	1.056	0.074	0.849	0.109	0.154	AF061569	102627_at		coding region determinant binding protein	putative c-myc mRNA binding protein
Brca1	9.421	4.025	2.185	1.374	0.187	1.243	0.169	0.121	U32446	102976_at		breast/ovarian cancer susceptibility protein homolog
Gna12	4.726	1.546	1.993	0.991	0.209	0.846	0.196	0.201	M63659	97227_at	G-alpha-12 protein	G-alpha-12 protein
2810417H13Rik	19.324	10.543	2.622	0.962	0.101	0.563	1	0.954	AI122538	100116_at	EST
Chek1	10.052	5.486	2.552	1.991	0.145	1.154	1.5	1.763	AF016583	103064_at		Chk1
Ccnd1	7.598	5.517	1.464	0.888	0.064	0.883	0.52	1.119	M64403	94231_at	cyclin-like protein	cyclin-like protein
Zac1	21.082	3.136	3.689	2.195	0.179	1.303	1.509	1.509	X95504	92502_at	zinc finger protein	zinc finger protein
Epha3	5.083	1.628	2.33	1.203	0.215	1.161	0.921	0.958	M68513	95298_at	receptor tyrosine kinase	receptor tyrosine kinase
Exo1	10.13	3.206	0.247	1.245	0.092	0.754	1.722	0.245	AJ238213	92244_at	Exo1 gene; exonuclease 1 homologue	exonuclease 1 homologue	putative mismatch repair protein
C80208	60.734	37.082	0.244	7.611	0.137	0.139	3.217	0.125	AI428843	97095_at	EST
Stk6	8.558	4.473	1.808	1.045	0.964	0.846	1.06	0.194	U80932	92639_at		serine/threonine kinase Ayk1
Fin16	12.782	6.04	1.973	1.146	0.94	0.657	0.898	0.106	U42385	97421_at		fibroblast growth factor inducible 16
Cdc20	15.378	6.531	2.237	1.058	0.833	0.816	0.683	0.098	AW061324	96319_at	EST
Mcmd5	6.855	4.677	1.29	0.695	0.837	0.68	0.647	0.11	D26090	100156_at	mCDC46; CDC46; mCDC46 protein; DNA replication	mCDC46 protein	possibly involved in DNA replication
Csrp2	6.599	4.873	2.112	0.806	0.4	0.437	0.347	0.045	D88792	93550_at	double LIM protein-1	double LIM protein-1
2310035M22Rik	14.773	7.772	2.378	1.444	0.53	0.384	0.53	0.107	AI851230	99149_at	EST
EST	9.64	4.949	2.264	1.914	0.976	1.51	0.593	0.37	AI843655	103071_at	EST
Mns1	8.518	3.955	1.324	1.032	0.611	0.837	0.518	0.229	D14849	103468_at	MNS1; meiosis-specific nuclear structural protein 1	meiosis-specific nuclear structural protein 1
2700084L22Rik	12.643	8.67	2.964	1.324	1.548	1.071	0.409	0.094	AA989957	100955_at	EST
2610200G18Rik	7.766	7.311	2.748	1.841	1.637	0.812	0.431	0.102	AI840035	104229_at	EST
EST	9.872	3.472	2.701	1.347	1.38	0.832	0.324	0.106	AI851599	92180_at	EST
Idb1	10.366	5.048	2.926	2.969	2.5	2.248	0.848	0.146	M31885	100050_at	helix-loop-helix DNA binding protein regulator; helix-loop-helix protein; regulatory protein
Bid	3.732	2.914	2.065	1.664	0.909	1.109	0.383	0.112	U75506	98433_at		BID	apoptotic death agonist
Lmyc1; Lmyc-1	5.266	4.354	2.622	1.988	0.645	0.347	0.024	0.026	X13945	102235_at	l-myc oncogene; myc oncogene	L-myc protein
2810052M02Rik	4.569	4.222	2.613	1.994	1.286	0.395	0.08	0.056	AI852196	95150_at	EST
Dcx	6.485	5.877	2.748	2.234	1.315	0.952	0.074	0.139	AB011678	102307_at	doublecortin	doublecortin
Cd1d1	4.859	4.286	2.531	1.907	0.723	0.869	0.164	0.297	M63695	103422_at	CD1 antigen; CD1.1 antigen; cell surface glycoprotein	CD1.1
Rbl1	10.882	4.565	1.932	1.587	0.977	1.181	0.169	0.183	U27177	104476_at		p107
Rrm1	8.055	4.593	2.2	1.599	0.635	0.808	0.136	0.132	K02927	100612_at	ribonucleotide reductase	ribonucleotide reductase M1
Cks1	7.401	4.688	2.378	2.122	1.069	0.973	0.146	0.082	AB025409	97468_at	sid1334p	sid1334p
Myb	17.378	4.155	2.594	1.706	0.441	0.345	0.108	0.039	M12848	92644_s_at	myb proto-oncogene; proto-oncogene	myb protein
Fabp7; Blbp; B-FABP	2.427	5.234	2.985	2.091	0.536	0.452	0.066	0.021	U04827	98967_at		brain fatty acid-binding protein
Cd24a	3.302	3.195	2	1.43	0.469	0.412	0.212	0.171	M58661	100600_at	heat-stable antigen	M1/69-J11d heat-stable antigen
H19; AI747191	4.724	3.488	3.032	1.623	0.443	0.223	0.113	0.133	X58196	93028_at	embryogenesis; H19 gene	H19 fetal liver mRNA
Bub1	45.199	25.305	5.957	1.12	0.473	0.142	0.069	0.096	AF002823	104097_at		mitotic checkpoint protein kinase
Sox11	6.755	5.652	1.693	1.112	0.376	0.284	0.151	0.269	AW107922	93669_f_at	EST
Knsl1	34.728	16.296	2.982	1.615	0.56	0.15	0.115	0.057	AJ223293	99541_at	eg5 gene; kinesin-related; mitotic motor protein	kinesin-related mitotic motor protein	essential for bipolar spindle
Mki67	57.132	23.44	5.192	1.5	0.323	0.027	0.099	0.058	X82786	99457_at	Ki-67 gene
Cdc45l	7.631	2.968	1.844	0.854	0.805	0.175	0.231	0.204	AF098068	102403_at		CDC45-related protein	putative DNA replication initiator protein
Dll1	11.822	6.199	3.747	1.635	0.837	0.137	0.138	0.107	X80903	92931_at	delta-like 1 gene	DELTA-like 1
Mapk7	5.412	5.48	2.606	2.297	0.579	0.075	0.066	0.1	AB019373	99000_at	ERK5	ERK5
Cyp1b1	5.207	2.52	2.259	2.241	0.991	0.103	0.125	0.149	X78445	99979_at	CYP1b gene; Cytochrome P450	cytochrome P450EF B1
Tpm3	7.779	6.182	4.185	5.7	4.453	0.199	0.155	0.172	X53753	93265_at	tropomyosin	"tropomyosin 3, gamma"
Casp6	4.501	5.953	3.812	2.47	0.15	0.171	0.666	0.048	Y13087	94458_at	caspase-6; cysteine protease	caspase-6	cysteine protease
2810052M02Rik	3.955	3.07	2.421	2.005	0.674	0.24	1.143	0.168	AW061307	95152_g_at	EST
Sox3	4.415	2.23	2.454	1.81	1.137	0.602	1.147	0.119	AA866668	103301_i_at	EST
Prim2	5.008	2.93	2.147	1.808	0.671	1.268	0.991	0.07	D13545	95549_at	primase large subunit; PRIM2	primase large subunit
Mcmd	19.063	6.257	1.198	1.509	1.719	0.117	1.647	1.146	X62154	100062_at	p1 protein	P1.m protein
EST	8.455	3.19	1.767	1.996	1.595	0.162	0.913	1.611	T25639	101203_r_at	EST
Lamb2; Lams; Lamb-2	5.114	3.346	1.556	0.945	0.781	0.117	0.756	2.33	U43541	101359_at		laminin beta 2
Tera-pending	5.831	1.832	2.546	1.754	0.558	0.108	0.632	0.535	U64033	103385_at		Tera
G7e	16.843	5.698	2.445	0.765	0.648	0.273	0.616	1.148	U69488	104333_at		viral envelope like protein
5730403J10Rik	30.453	10.217	1.825	0.917	0.815	0.083	0.338	0.555	AI049398	102354_at	EST
2310021G01Rik	21.101	7.324	2.616	1.189	0.752	0.094	0.494	1.011	AI606257	95063_at	EST
Zfp36l1	7.004	3.858	1.687	1.356	0.959	0.675	0.671	0.919	M58566	93324_at	TIS11 gene	"zinc finger protein 36, C3H type-like 1"	TIS11 primary response gene
Birc5	35.835	15.646	4.746	1.08	0.142	0.181	0.778	0.492	AB013819	101521_at	TIAP; Tiap	TIAP
Tacc3	26.143	10.434	4.294	0.696	0.109	0.061	0.184	0.364	AW209238	97238_at	EST
Fgf3; Fgf-3; Int-2; Int-P	12.307	3.128	3.42	1.187	0.329	0.186	0.254	1.402	Y00848	92957_at	int-2 gene; oncogene	int-2
Cdc25c	12.551	7.428	3.301	0.19	1.566	0.176	0.164	1.673	L16926	102934_s_at	cdc25 phosphatase	cdc25 phosphatase
Hells	26.311	8.368	2.255	0.159	1.217	0.184	0.072	3.865	U25691	93228_at		lymphocyte specific helicase
Mad3	12.685	8.268	3.298	0.632	1.235	0.521	0.123	1.327	U32394	103237_at		Max-interacting transcriptional repressor
TK	5.016	3.174	1.47	0.881	1.064	0.66	0.37	0.907	X60980	96081_at	regulatory sequences; thymidine kinase; TK gene	thymidine kinase
EST	19.139	5.828	2.169	0.731	0.49	0.667	0.043	0.547	AW213883	95753_at	EST
Plk-ps1	5.431	3.669	1.47	1.022	1.097	0.926	0.178	1.506	U73170	101350_g_at
Notch1	3.934	4.216	2.576	1.355	0.458	0.21	0.058	0.393	Z11886	97497_at	notch-1	notch-1
6230425C21Rik	6.501	4.203	2.26	1.811	1.11	0.672	0.053	0.565	AA881438	97967_at	EST
Fzd2	6.435	3.604	3.015	2.366	1.326	0.104	0.052	0.902	AW123618	93681_at	EST
Smoh	5.966	2.859	2.656	1.858	1.144	0.106	0.098	1.015	AF089721	96812_at
EST	2.926	2.748	1.44	1.071	0.433	0.549	0.358	0.586	AF109906	92656_at		RD; Bf; C2; G9A; NG22; HSP70; HSC70t; smRNP; G7A
EST	36.632	16.182	3.616	1.107	0.095	0.132	0.095	0.764	AI591702	96168_at	EST
EST	26.167	14.983	2.816	1.188	0.084	1.107	0.038	0.462	AI595322	93441_at	EST
1110037A17Rik	12.763	6.935	2.089	0.788	0.147	0.439	0.054	0.352	AW123269	96784_at	EST
Tnfip6	7.553	6.216	3.937	2.822	0.118	0.553	0.107	1.236	U83903	98474_r_at		TNF-stimulated gene 6 protein
Crip	3.219	5.055	2.066	2.014	0.095	0.075	0.068	0.489	M13018	94061_at	cysteine-rich intestinal protein	cysteine rich intestinal protein
Pole2	25.152	15.921	2.242	0.089	0.16	0.185	1.345	2.391	AF036898	101920_at		DNA polymerase epsilon small subunit
Rrm2	20.406	4.463	2.411	0.132	0.621	0.644	0.873	0.967	M14223	102001_at	reductase; ribonucleotide reductase	ribonucleotide reductase M2
E2f1	69.569	31.429	13.126	0.291	0.173	0.162	1.653	0.197	L21973	102963_at		E2F transcription factor 1
Mybl2	9.256	4.219	2.201	0.185	0.202	0.317	1.827	0.316	X70472	100023_at	B-myb gene; proto-oncogene	myeloblastosis oncogene-like 2
2410006H10Rik	51.343	53.968	1.864	0.148	3.085	2.474	2.962	0.126	AI317217	94971_at	EST
Pros1	4.19	2.789	1.985	0.196	0.946	0.913	1.116	0.228	L27439	104728_at	protein S	protein S
Mcmd7	6.71	2.845	2.001	1.433	0.67	0.618	0.54	0.445	D26091	93356_at	mCDC47; minichromosome maintenance (Mcm) protein; mouse protein CDC47	mCDC47	possibly involved in DNA replication
Ezh2	6.121	3.056	1.859	1.535	0.782	0.696	0.478	0.491	U52951	99917_at	vertebrate polycomb-group gene	mEnx-1
Stk18	8.258	3.619	1.686	1.405	0.799	0.755	0.611	0.464	L29480	98996_at	serine/threonine kinase	serine/threonine kinase
Tead2	7.125	3.723	2.261	1.3	0.405	0.509	0.433	0.468	Y10026	96940_at	TEF1 gene; transcription factor	transcription factor TEF-1
Ccnd1	8.397	3.997	1.515	0.645	0.254	0.216	0.227	0.293	AI849928	94232_at	EST
Cdc2a	49.55	30.568	5.783	1.46	0.168	0.162	0.083	0.085	M38724	100128_at	cell cycle protein	cell cycle protein p34
Ckap2	27.322	16.635	3.829	1.167	0.183	0.168	0.13	0.105	AI121796	104322_at	EST
Sox11	6.637	5.918	2.032	1.198	0.436	0.283	0.223	0.185	AF009414	101631_at		SOX11
Hes6	6.118	3.852	2.151	1.347	0.56	0.457	0.362	0.282	AW048812	97334_at	EST
Tyms	5.393	3.763	1.602	1.057	0.408	0.347	0.427	0.286	AU044050	93237_s_at	EST
Prdx4	4.032	3.942	1.682	1.065	0.645	0.597	0.419	0.311	U96746	93495_at		antioxidant enzyme AOE372
3110003A17Rik	3.624	3.818	1.519	0.878	0.621	0.626	0.376	0.377	AA833425	96135_at	EST
2310046G15Rik	7.359	5.369	2.642	1.938	0.917	1.091	0.779	0.557	AW228316	94238_at	EST
EST	4.665	3.523	1.717	1.005	0.723	0.756	0.663	0.453	AF109905	95654_at		Hsc70t; smRNP; G7A; NG23; MutS homolog; CLCP; NG24; NG25; NG26
1110038L14Rik	12.824	10.319	2.131	0.889	0.46	0.645	0.507	0.266	AA681998	97527_at	EST
EST	5	5.779	1.584	0.557	0.343	0.25	0.228	0.27	M33988	94805_f_at	histone H2A.1	histone H2A.1
Top2a	276.752	104.256	23.869	0.398	0.139	0.183	0.103	0.373	U01915	99578_at		DNA topoisomerase IIalpha	DNA relaxing enzyme
Stk5	38.08	26.419	11.371	0.211	0.205	0.187	0.216	0.195	D21099	98469_at	MMSTK1; serine/threonine kinase; STK-1; protein kinase	STK-1
Ascl1	38.734	20.259	9.298	0.416	0.176	0.102	0.104	0.112	M95603	102238_at	helix-loop-helix protein	helix-loop-helix protein
Ttk	10.578	5.582	1.621	0.441	0.454	0.464	0.718	0.481	M86377	103201_at	esk kinase	esk kinase
Hmgb2	8.74	7.254	1.941	0.993	0.575	0.666	0.986	0.578	X67668	93250_r_at	high mobility group 2 protein	high mobility group 2 protein
Six6	8.65	7.561	1.109	0.22	0.228	0.141	0.202	0.227	AJ011787	101797_at	OPTX2 gene; Optx2 protein; Six9 gene; Six9 protein	Six9 protein
Ccnb2	6.629	3.231	1.166	0.478	0.476	0.393	0.385	0.485	X66032	94294_at	cell cycle regulatory protein; cycB2 gene	cyclin B2
Prim1	6.849	3.799	1.538	0.687	0.753	0.739	0.653	0.558	J04620	96772_at	RNA polymerase; primase; primase p49 subunit	primase p49 subunit
EST	13.045	6.158	1.723	0.765	0.706	0.414	0.484	0.35	AA856349	95032_at	EST
Ect2	9.359	4.233	1.132	0.65	0.584	0.553	0.444	0.535	L11316	97411_at	oncogene	ect2 oncogene
Fgf15	258.193	47.233	0.667	0.331	0.215	0.206	0.162	0.174	AF007268	97721_at		fibroblast growth factor
C79407	6.947	4.493	1.152	0.717	0.539	0.567	0.7	0.599	AI450597	103308_at	EST
Calmbp1	152.561	72.419	1.067	0.145	0.276	0.195	0.205	0.249	AF062378	102632_at		calmodulin-binding protein SHA1
4831429J16Rik	8.708	4.322	1.615	0.534	0.823	0.928	0.547	0.644	AW122331	97295_at	EST
Atoh7	105.242	17.884	0.209	0.185	0.209	0.22	0.247	0.36	AF071223	101811_at		transcription factor Math5
Kifc1	31.363	14.207	0.214	0.204	0.17	0.21	0.209	0.22	D49544	98471_f_at	KifC1; KIFC1	KIFC1	kinesin-related mechanochemical ATPase
Epha2	14.136	3.307	0.458	0.258	0.182	0.219	0.747	0.243	U07634	103980_at		receptor-protein tyrosine kinase
Vrk1	9.971	5.919	0.256	0.238	0.218	0.678	0.178	0.092	AF080253	97393_at		serine/threonine protein kinase 51PK(L)
Foxm1	39.254	5.626	0.296	0.207	0.248	2.898	0.18	0.253	Y11245	98305_at	transcription factor	winged-helix transcription factor
C77459	55.207	28.48	0.443	0.634	3.272	1.09	0.201	0.188	AI510131	98489_at	EST
Pdlim1	10.646	6.745	0.357	0.255	1.539	0.132	0.12	0.118	AF053367	100554_at		carboxyl terminal LIM domain protein
Chaf1a	4.762	5.158	0.188	0.281	1.076	0.211	0.166	0.188	AJ132771	95527_at	CAF-Ip150 gene; chromatin assembly factor-I; p150 subunit	chromatin assembly factor-I p150 subunit	DNA replication-dependent assembly of nucleosomes
Grb10	7.93	0.784	0.24	0.214	0.276	0.153	1.571	0.278	U18996	93691_s_at		growth factor receptor binding protein Grb10
1700003K02Rik	8.637	2.46	0.265	0.144	0.191	1.194	1.618	1.287	AW213865	97364_at	EST
Hoxa13	4.605	7.113	1.569	0.325	0.197	7.198	0.241	0.247	U59322	94636_at		transcription factor HOXA13
Cdk2	5.847	3.938	0.127	2.556	0.162	0.102	0.197	2.192	AJ223732	94411_at	CDK2 gene; cyclin dependent kinase	cyclin dependent kinase
Xtrp2	5.946	3.461	0.157	3.502	0.2	2.143	0.199	2.638	AF075267	97465_at		orphan transporter isoform A8