Mouse Retinal Gene Expression

The Friedlander Laboratory
Department of Cell Biology

Michael I. Dorrell, Edith Aguilar, Christoph Weber, Martin Friedlander. IOVS
The Scripps Research Institute, La Jolla, CA

Microarray Home Statistical Analyses Gene Search

Cluster 6

Genes with a constant increase in expression (steep slope)

Clusters 2, 3, and 6 represent genes expressed during post-natal mouse retina development, whose expression is low at birth and then generally increases throughout post-natal development. Visual processes generally begin around P8 in the mouse and are fully functional around P14 when mouse eyes open and the vision process officially begins. Although many developmental events are occurring simultaneously and caution should be taken when predicting gene functions from expression data alone, these genes have a higher likelihood of being involved in visual function. This includes genes directly involved in the transfer of light-induced visual signals, and genes whose expression is required to prepare and maintain the photoreceptors and other neural layers during the visual process. Cluster 6 genes generally have drastic increases in expression beginning between around 1 week after birth. This cluster includes genes known to be involved in the direct transfer of light-activated signals.

Normalized chip to chip and per gene
"po-adult, triplicate"

Common Name P0 P4 P8 P10 P12 P14 P21 Adult Genbank Affy ID# Keywords Product Function
Hcls1 0.09 0.085 0.128 0.123 1.36 3.123 9.648 12.137 X84797 99461_at cortactin gene; HS1 gene hematopoietic specific protein 1
Cdr2 0.195 0.206 0.196 0.268 1.138 1.842 3.256 3.594 U88588 93094_at cerebellar degeneration-related 2
Sh2d1a 0.086 0.08 0.073 0.099 3.82 3.321 12.154 11.544 AF097632 103279_at SLAM-associated protein 1
Wisp1 0.224 0.261 0.374 0.496 1.271 1.86 4.195 2.68 AF100777 102044_at connective tissue growth factor related protein WISP-1
2700053F16Rik 0.489 0.389 0.645 0.665 1.495 1.954 3.66 2.919 AA755004 96831_at EST
Aqp4 0.16 0.089 0.124 0.385 2.142 2.609 4.082 6.459 U88623 102704_at aquaporin-4
Slc6a6 0.443 0.527 0.742 0.929 2.666 2.302 3.578 4.811 AI042802 94405_at EST
C80501 0.311 0.38 0.438 0.661 1.902 1.895 2.502 3.156 AI848623 97383_at EST
Usp2 0.467 0.326 0.568 0.66 1.567 1.771 3.359 4.902 AI846522 92820_at EST
Gabrr2 0.337 0.056 0.271 0.157 1.967 2.862 4.786 7.976 AF024621 99839_at gamma-aminobutyric acid receptor rho2 subunit
Tnfaip3 0.068 0.036 0.16 0.194 6.954 13.02 37.168 1.666 U19463 99392_at zinc finger protein; apoptosis A20 protein
Drd4; D4R; Drd-4 0.128 0.122 0.132 0.243 3.022 4.014 4.584 2.997 U19880 97755_at D4 dopamine receptor
Polg2 0.321 0.292 0.347 0.653 1.723 2.404 2.345 1.816 AF006072 93699_at mitochondrial DNA polymerase accessory subunit
Chst2 0.43 0.35 0.921 2.116 2.298 2.944 3.403 4.035 AB011451 102639_at N-acetylglucosamine-6-O-sulfotransferase N-acetylglucosamine-6-O-sulfotransferase This enzyme catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate to the position 6 of non-reducing GlcNAc in de-galactosylated L1L1.
Cals1 0.148 0.086 0.46 1.31 2.548 3.766 4.501 5.393 X61397 102773_at carbonic dehydratase homologue carbonic anhydrase-related polypeptide
Pcp2 0.403 0.257 0.894 1.673 3.179 3.395 3.512 3.354 M21532 102376_r_at PCD-5 protein Purkinje cell protein 2 (L7)
Aqp4 0.064 0.017 0.228 0.497 1.581 2.627 3.579 3.699 U48398 102703_s_at mercurial-insensitive water channel 2
Pde6a 0.081 0.069 0.245 0.443 1.328 2.206 4.312 3.951 X60664 100696_at "3',5'-cyclic-GMP phosphodiesterase; cGMP phosphodiesterase; MPA gene; rod phosphodiesterase; rod phosphodiesterase alpha subunit" rod phosphodiesterase alpha subunit
Vtn 0.082 0.028 0.204 0.319 2.033 3.357 7.969 7.504 M77123 98549_at vitronectin vitronectin
Akp2 0.244 0.178 0.405 0.541 1.986 2.216 2.808 2.558 J02980 92796_at alkaline phosphatase; orthophosphoric-monoester phosphohydrolase alkaline phosphatase
Gnat1; Gnat-1; Tralpha; transducin 0.01 0.01 0.063 0.136 1.329 3.412 4.471 3.334 M25513 99860_at GTP-binding protein; transducin "guanine nucleotide binding protein, alpha transducing 1"
Dio2 0.284 0.254 0.614 0.828 2.297 2.868 2.184 2.231 AF096875 103438_at type 2 deiodinase
Og9x 0.042 0.041 0.049 0.71 1.171 5.705 6.811 4.32 U65068 93668_at SEBOX
Tm4sf9-pending 0.339 0.262 0.315 0.645 1.159 1.684 2.527 1.274 AI877157 92426_at EST
Slc17a1 0.241 0.062 0.114 0.927 1.397 2.214 6.236 6.435 X77241 96077_at NPT1 gene; sodium-dependent phosphate cotransporter sodium-phosphate transport system 1
Slc16a1 0.351 0.121 0.179 0.656 1.073 2.107 3.655 2.797 AF058055 101588_at monocarboxylate transporter 1
EST 0.543 0.371 0.567 0.925 1.321 1.727 2.256 2.101 AW122860 93130_at EST
Rasgrf1 0.042 0.214 0.369 1.223 1.394 3.066 7.195 7.219 L20899 96313_at CDC25 gene; cell division; cell division cycle CDC25 homolog
EST 0.032 0.114 0.495 0.774 2.116 2.509 3.617 3.282 AA755260 96134_at EST
Abca4 0.087 0.264 0.583 0.802 1.831 2.162 3.018 2.847 AF000149 97730_at ATP-binding cassette transporter
Calb1; CB; Calb-1; Brain-2 0.143 0.41 0.808 1.034 1.474 2.452 3.216 2.676 D26352 98133_at Ca2+-binding protein; calbindin-D28k; spot35 spot35/calbindin-D28k
Guca1a 0.071 0.275 0.452 0.499 1.549 2.868 5.411 5.656 L36860 103038_at calcium-binding protein; guanylate cyclase activating protein; membrane-associated protein guanylate cyclase activating protein calcium-binding protein
Sh3d2a 0.346 0.713 1.053 1.058 1.418 2.422 2.715 2.726 U58886 92673_at endophilin I
Gnb5 0.256 0.574 0.718 1.063 2.264 3.02 3.598 3.191 L34290 100122_at guanine nucleotide regulatory protein beta subunit guanine nucleotide regulatory protein
Tac2 0.061 0.127 0.221 0.569 2.246 2.9 3.88 4.067 D14423 103548_at neurokinin B; neuromedin K; preprotachykinin B; tachykinin preprotachykinin B
Pla2g1br 0.13 0.227 0.53 0.664 1.8 2.451 3.034 2.96 D30779 98853_at phospholipase A2 receptor phospholipase A2 receptor
Opn1mw 0.053 0.175 0.225 0.314 1.705 4.486 5.712 4.574 AI462500 101679_at EST
Tnfsf12 0.163 0.24 0.538 0.786 1.852 1.906 2.786 3.582 AF030100 93917_at TWEAK
Dnm 0.388 0.537 0.995 1.127 1.859 1.835 2.721 3.11 L31397 103030_at GTPase; dynamin; endocytosis dynamin
Sncb 0.531 0.675 1.153 1.2 2.364 2.071 2.954 4.237 AI839708 100510_at EST
Dnm 0.433 0.699 0.922 1.11 2.07 1.677 2.54 3.246 L31397 103031_g_at GTPase; dynamin; endocytosis dynamin
Eef1a2 0.452 0.852 0.869 1.189 2.471 2.113 3.106 3.421 L26479 94429_at elongation factor-1 alpha elongation factor-1 alpha
Scyd1 0.372 0.651 0.722 0.972 1.773 1.598 2.436 2.649 U92565 98008_at fractalkine
D6Wsu176e 0.447 0.638 0.777 1.154 1.807 1.868 2.967 3.286 AA733372 97770_s_at EST
1500005G05Rik 0.391 0.44 0.848 0.993 1.316 1.738 3.349 3.447 AI839690 103922_f_at EST
D6Wsu176e 0.267 0.377 0.602 0.764 1.157 1.756 3.346 2.638 AW125506 95541_at EST
Gas7 0.256 0.373 0.588 0.545 1.268 1.713 2.882 3.146 U19860 104678_at growth arrest specific 7
Clu 0.235 0.339 0.531 0.706 1.337 1.82 3.428 4.016 D14077 95286_at secretory protein; sulfated glycoprotein-2 sulfated glycoprotein-2
Hsp70-3 0.25 0.376 0.435 0.488 0.961 1.419 2.516 3.258 M12571 93875_at 68 kDa heat shock protein
EST 0.246 0.187 0.43 0.56 0.652 1.755 1.308 2.561 AA419684 95183_i_at EST
Aqp1 0.115 0.081 0.137 0.14 0.857 30.904 98.692 66.535 L02914 93330_at aquaporin-1 growth factor-induced delayed early response protein
Zap70 0.16 0.198 0.397 0.092 0.393 1.655 5.091 5.691 AI386093 93662_s_at EST
EST 0.214 0.461 0.437 0.401 0.835 1.615 4.535 4.766 X05862 93833_s_at DNA-binding protein; histone; histone H2A; histone H2B
Sgk 0.248 0.3 0.27 0.415 0.638 1.104 4.653 7.741 AW046181 97890_at EST
Fgf1 0.418 0.074 0.44 0.641 1.284 1.765 3.033 1.473 M30641 100494_at acidic fibroblast growth factor fibroblast growth factor 1
Osmr 1.196 0.137 0.69 1.117 2.055 1.831 3.584 4.984 AB015978 102255_at oncostatin M receptor beta; Osmr oncostatin M receptor beta
Sema3f 0.608 0.754 0.208 1.503 2.033 1.312 2.742 2.222 AF080090 102623_at semaphorin IV isoform b
Prp 0.297 0.168 0.054 0.297 1.265 2.283 5.433 6.496 M23236 93650_i_at LIM repetitive element; proline-rich protein proline-rich protein
Gstt1 0.432 0.51 0.087 0.567 2.435 2.159 2.363 3.387 X98055 95019_at glutathione S-transferase theta; GSTT1 gene glutathione S-transferase theta phase II conjugation enzyme
Selenbp1 0.075 0.673 0.902 0.992 1.586 2.379 2.488 1.464 M32032 100596_at Selenium-binding protein selenium binding protein 1
EST 0.121 1.173 1.015 1.579 1.664 2.402 2.818 2.034 AI846673 103478_at EST
C76628 0.146 2.053 1.511 1.46 3.593 2.742 4.187 4.035 C76628 101220_at EST
EST 0.068 1.259 1.05 0.915 1.757 2.612 3.109 2.096 AI596540 96536_at EST
Scn1a 0.088 0.877 0.76 0.954 1.808 2.145 2.55 2.93 L42339 94201_at sodium channel 3 sodium channel 3
Il5; Il-5 0.195 1.257 1.28 1.526 2.496 3.257 2.599 3.54 X06271 98374_at B-cell growth factor II; colony stimulating factor; eosinophil differentiation factor; interleukin 5; lymphokine IL-5
Igh 0.152 1.305 1.05 1.159 1.465 2.505 3.465 3.16 AF042086 97577_f_at immunoglobulin heavy chain V-DSP2.7-JH2 region
Prph2 0.044 0.837 1.878 1.968 2.822 2.938 4.017 4.554 X14770 101169_at photoreceptor; rds gene peripherin 2
EST 0.2 1.116 2.085 2.353 3.278 2.657 2.826 3.518 AI854450 103331_at EST
Lhx3 0.115 0.639 1.665 2.261 2.413 2.703 2.6 3.574 L38248 102902_at homeodomain protein
Slc7a8 0.024 0.329 0.979 1.65 2.074 2.312 1.985 2.163 AW122706 104214_at EST
Rom1 0.073 0.459 1.286 1.641 2.208 2.374 2.599 2.604 M96760 93453_at disk morphogenesis; disk rim; peripherin-related protein; rod photoreceptor; transmembrane protein rod outer segment membrane protein 1
Sag 0.057 0.488 1.353 1.601 2.387 2.515 2.46 2.704 M24086 94150_at S-antigen; Sag gene S-antigen
Pde6b 0.01 0.287 1.162 1.458 2.105 2.417 2.708 2.83 X55968 94701_at "3',5'-cyclic-nucleotide phosphodiesterase; membrane protein; transducin" "phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide"
junB 0.059 0.81 2.276 2.575 2.173 3.394 3.329 6.06 U20735 102362_i_at transcription factor junB
Slc12a4 0.109 1.059 1.914 1.447 1.716 2.7 2.551 3.452 AF047339 92450_at erythroid K:Cl cotransporter
AW112037 0.089 0.335 0.842 0.817 1.724 2.065 2.313 1.496 AW122808 104282_at EST
EST 0.079 0.24 1.036 1.203 1.545 2.193 3.207 2.055 AA690218 98569_at EST
Rcvrn 0.015 0.11 0.626 1.104 2.724 2.659 2.979 2.578 X66196 101151_at 23 kDa protein; photoreceptor specific 23 kDa photoreceptor cell-specific protein
opsin 0.01 0.06 0.425 0.944 2.849 3.007 3.395 3.022 M36699 96567_at opsin opsin
Pde6g 0.039 0.21 0.986 1.296 2.068 2.389 2.537 2.659 Y00746 97732_at "3',5'-cyclic-nucleotide phosphodiesterase; cyclic GMP phosphodiesterase gamma" "phosphodiesterase 6G, cGMP-specific, rod, gamma"
Mod1 0.308 0.868 1.223 1.419 1.739 1.842 2.581 2.427 J02652 101082_at malate NADP oxidoreductase; malic enzyme malate oxidoreductase
Ache 0.104 0.654 0.93 1.545 2.33 1.881 2.52 3.188 X56518 104650_at acetylcholinesterase acetylcholinesterase
C030048H19Rik 0.095 0.642 0.914 1.323 2.657 2.354 3.625 4.925 AW122114 92526_f_at EST
Npn1 0.277 1.18 1.305 1.54 2.294 1.974 3.184 4.31 Z31360 101168_at P/L01 gene
Ptgds 0.021 0.335 0.515 0.723 1.092 1.568 2.698 5.878 AB006361 92546_r_at prostaglandin D synthetase prostaglandin D synthetase
Usp2 0.093 0.626 0.569 0.638 1.446 1.584 3.551 4.893 AF079565 92821_at ubiquitin-specific protease UBP41
Ptgds 0.166 0.508 0.846 0.952 1.525 1.916 3.259 7.143 AB006361 92545_f_at prostaglandin D synthetase prostaglandin D synthetase
Rgr 0.205 0.671 0.768 1.098 1.442 2.04 2.847 4.814 AF076930 95331_at RGR opsin
Ak4 0.182 0.863 1.892 1.357 1.447 1.765 4.587 4.925 AB020239 99521_at mAK3b; adenylate kinase 3 adenylate kinase 3
Krt1-18; K18 0.283 0.922 1.172 1.028 1.184 1.951 3.558 2.765 M22832 94270_at cytokeratin cytokeratin
Mef2c 0.116 2.05 0.976 2.111 3.925 1.83 17.315 26.732 L13171 104590_at DNA-binding protein; myocyte-specific enhancer factor 2; tissue specific expression; transcription factor myocyte enhancer factor 2C
Cav 0.251 0.842 0.373 1.592 1.47 3.156 2.945 2.944 U07645 97849_at "caveolin, caveolae, adipocytes, endothelial cells" caveolin-1
Bhlhb2 0.084 0.64 0.075 1.108 2.196 2.684 6.892 9.586 Y07836 104701_at basic-helix-loop-helix protein basic-helix-loop-helix protein
Hk2; HKII; AI642394 0.151 1.257 0.151 1.186 1.42 2.017 8.732 17.697 Y11666 94375_at hexokinase II hexokinase II
Pcsk6 0.095 0.875 0.188 1.829 0.223 2.346 2.75 3.313 D50060 101196_at PACE4A PACE4A
Crybb2 0.08 0.063 0.476 1.769 1.402 3.879 4.991 2.256 M60559 100688_at beta-B2 crystallin beta-B2 crystallin structural protein
Cacnb2 0.207 0.207 0.802 0.815 1.027 2.003 2.892 1.699 L20343 100757_at L-type calcium channel beta subunit isoform
Gnb1 0.24 0.271 0.768 0.995 1.503 2.309 2.881 1.885 U29055 94853_at G protein beta 36 subunit
Pla2g5 0.215 0.163 1 1.032 1.34 2.344 2.567 1.347 U66873 101328_at phospholipase A2 group 5
Rs1h 0.042 0.031 0.585 0.913 0.507 3.756 5.791 3.544 AJ011381 101702_at X-linked juvenile retinoschisis protein; Xlrs1 gene X-linked juvenile retinoschisis protein
EST 0.306 0.087 1.326 1.63 1.922 2.442 2.169 2.051 Y12650 104014_at
4930406E12Rik 0.597 0.115 1.885 1.643 2.627 2.179 3.236 2.809 AW125311 98445_at EST
Bcl6 0.225 0.084 1.158 1.055 1.975 2.403 5.358 5.882 U41465 103015_at BCL-6
Gsg1 0.361 0.16 0.946 1.312 1.901 2.035 2.74 2.424 D87325 96620_at GSG1 GSG1
Cacna2d3 0.574 0.119 1.071 1.577 1.701 2.485 3.793 3.604 AJ010949 98300_at calcium channel alpha-2-delta-C subunit calcium channel alpha-2-delta-C subunit
R74640 0.135 0.085 1.109 1.013 3.06 1.388 2.892 4.12 AW122995 93159_at EST
Hzf-pending 0.499 0.401 1.067 1.143 1.875 1.592 2.573 3.235 AI848518 102691_at EST
Pacsin1 0.396 0.394 0.93 0.893 1.633 1.722 2.612 3.499 X85124 92949_at pacsin gene PACSIN
Sdccagg28 0.529 0.492 1.189 1.036 1.791 1.601 2.922 3.271 AW049732 96735_at EST
Rdh5 0.031 0.068 0.428 0.746 1.559 1.44 2.743 4.198 AF033195 101431_at 9-cis-retinol dehydrogenase
C030048H19Rik 0.088 0.144 0.889 1.391 2.051 2.028 3.21 5.517 AW122114 92525_i_at EST
beta 1 0.076 0.102 0.659 0.931 2.122 1.977 2.486 3.445 L48687 102808_at Na+ channel; beta-1 subunit; beta-subunit; sodium channel; voltage-dependent Na+ channel voltage-dependent Na+ channel beta-1 subunit
Slc29a2 0.077 0.119 0.622 1.447 2.288 2.171 3.072 2.702 X86682 92950_at HNP36 gene HNP36 protein
Gabrr1 0.077 0.084 0.66 1.975 2.571 3.065 2.873 3.391 AF024620 100675_at gamma-aminobutyric acid receptor rho1 subunit
EST 0.06 0.104 0.367 1.37 2.874 1.664 2.635 3.449 AI853899 95641_at EST
Agt; Aogen; AI265500 0.144 0.152 2.019 2.862 5.506 4.986 3.569 5.539 AF045887 101887_at angiotensinogen precursor
Slc25a17 0.138 0.159 1.351 1.916 3.002 2.111 2.639 3.754 AW124470 97473_at EST
Hcn2 0.152 0.202 1.371 2.328 2.645 1.899 1.939 5.12 AJ225122 94194_s_at cation channel; HAC1 "hyperpolarization-activated cation channel, HAC1"
Cpx2-pending 0.052 0.116 0.874 0.979 1.126 1.762 1.901 1.292 AF017639 102226_at carboxypeptidase X2
Cncg 0.01 0.033 0.671 1.269 2.638 4.139 4.819 2.427 M84742 95389_at cGMP-gated cation channel protein cGMP-gated cation channel protein
Gzmm 0.046 0.095 1.003 1.527 2.007 2.293 2.741 2.686 AB015728 95363_at granzyme M granzyme M
D2Bwg0891e 0.068 0.113 1.403 1.617 1.811 2.144 2.451 2.104 AW121364 99641_at EST
Ryr2 0.062 0.206 2.097 1.788 1.925 2.731 2.497 2.699 X78667 102653_at ryanodine receptor; RYR2 gene "ryanodine receptor 2, cardiac"
D6Wsu176e 0.093 0.304 1.757 1.956 3.007 2.739 2.503 3.693 AA733372 97771_r_at EST
Ctgf 0.034 0.146 1.301 1.262 2.441 2.688 2.818 4.906 M70642 93294_at cysteine-rich protein; growth factor-inducible gene FISP-12 protein
Grid1 0.183 0.215 1.12 1.427 1.356 2.482 1.931 2.77 D10171 94619_at delta 1 subunit; glutamate receptor channel glutamate receptor channel subunit delta-1
Vcam1 0.066 0.109 1.334 4.048 6.175 5.42 2.339 2.653 M84487 92558_at vascular cell adhesion molecule-1 vascular cell adhesion molecule-1
Kcnb1 0.088 0.178 0.642 1.258 1.362 2.103 5.15 0.397 M64228 101308_at ion channel; potassium channel protein potassium channel protein
Gabra1 0.114 0.049 0.541 1.128 1.13 2.205 3.141 0.316 X61430 92938_at GABA-A receptor alpha-1 subunit; ligand-gated channel; membrane protein GABA A receptor alpha 1 subunit
F3 0.079 0.135 1.355 1.462 2.157 0.241 5.745 7.004 M26071 97689_at membrane-bound glycoprotein; tissue factor coagulation factor III
Mup4 0.237 0.153 0.842 0.388 1.767 0.199 2.251 9.182 M16358 101682_f_at major urinary protein major urinary protein IV
Prrx2 0.214 0.176 3.331 0.146 2.255 4.78 2.02 8.294 X52875 103327_at homeobox gene; homeodomain region; Prx2 homeobox gene "surface antigen, homeo box of paired rule"
AI266885 0.227 1.106 0.124 0.166 0.307 0.222 4.114 2.46 AI266885 104213_at EST

Common Name	P0	P4	P8	P10	P12	P14	P21	Adult	Genbank	Affy ID#	Keywords	Product	Function
Hcls1	0.09	0.085	0.128	0.123	1.36	3.123	9.648	12.137	X84797	99461_at	cortactin gene; HS1 gene	hematopoietic specific protein 1
Cdr2	0.195	0.206	0.196	0.268	1.138	1.842	3.256	3.594	U88588	93094_at		cerebellar degeneration-related 2
Sh2d1a	0.086	0.08	0.073	0.099	3.82	3.321	12.154	11.544	AF097632	103279_at		SLAM-associated protein 1
Wisp1	0.224	0.261	0.374	0.496	1.271	1.86	4.195	2.68	AF100777	102044_at		connective tissue growth factor related protein WISP-1
2700053F16Rik	0.489	0.389	0.645	0.665	1.495	1.954	3.66	2.919	AA755004	96831_at	EST
Aqp4	0.16	0.089	0.124	0.385	2.142	2.609	4.082	6.459	U88623	102704_at		aquaporin-4
Slc6a6	0.443	0.527	0.742	0.929	2.666	2.302	3.578	4.811	AI042802	94405_at	EST
C80501	0.311	0.38	0.438	0.661	1.902	1.895	2.502	3.156	AI848623	97383_at	EST
Usp2	0.467	0.326	0.568	0.66	1.567	1.771	3.359	4.902	AI846522	92820_at	EST
Gabrr2	0.337	0.056	0.271	0.157	1.967	2.862	4.786	7.976	AF024621	99839_at		gamma-aminobutyric acid receptor rho2 subunit
Tnfaip3	0.068	0.036	0.16	0.194	6.954	13.02	37.168	1.666	U19463	99392_at	zinc finger protein; apoptosis	A20 protein
Drd4; D4R; Drd-4	0.128	0.122	0.132	0.243	3.022	4.014	4.584	2.997	U19880	97755_at		D4 dopamine receptor
Polg2	0.321	0.292	0.347	0.653	1.723	2.404	2.345	1.816	AF006072	93699_at		mitochondrial DNA polymerase accessory subunit
Chst2	0.43	0.35	0.921	2.116	2.298	2.944	3.403	4.035	AB011451	102639_at	N-acetylglucosamine-6-O-sulfotransferase	N-acetylglucosamine-6-O-sulfotransferase	This enzyme catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate to the position 6 of non-reducing GlcNAc in de-galactosylated L1L1.
Cals1	0.148	0.086	0.46	1.31	2.548	3.766	4.501	5.393	X61397	102773_at	carbonic dehydratase homologue	carbonic anhydrase-related polypeptide
Pcp2	0.403	0.257	0.894	1.673	3.179	3.395	3.512	3.354	M21532	102376_r_at	PCD-5 protein	Purkinje cell protein 2 (L7)
Aqp4	0.064	0.017	0.228	0.497	1.581	2.627	3.579	3.699	U48398	102703_s_at		mercurial-insensitive water channel 2
Pde6a	0.081	0.069	0.245	0.443	1.328	2.206	4.312	3.951	X60664	100696_at	"3',5'-cyclic-GMP phosphodiesterase; cGMP phosphodiesterase; MPA gene; rod phosphodiesterase; rod phosphodiesterase alpha subunit"	rod phosphodiesterase alpha subunit
Vtn	0.082	0.028	0.204	0.319	2.033	3.357	7.969	7.504	M77123	98549_at	vitronectin	vitronectin
Akp2	0.244	0.178	0.405	0.541	1.986	2.216	2.808	2.558	J02980	92796_at	alkaline phosphatase; orthophosphoric-monoester phosphohydrolase	alkaline phosphatase
Gnat1; Gnat-1; Tralpha; transducin	0.01	0.01	0.063	0.136	1.329	3.412	4.471	3.334	M25513	99860_at	GTP-binding protein; transducin	"guanine nucleotide binding protein, alpha transducing 1"
Dio2	0.284	0.254	0.614	0.828	2.297	2.868	2.184	2.231	AF096875	103438_at		type 2 deiodinase
Og9x	0.042	0.041	0.049	0.71	1.171	5.705	6.811	4.32	U65068	93668_at		SEBOX
Tm4sf9-pending	0.339	0.262	0.315	0.645	1.159	1.684	2.527	1.274	AI877157	92426_at	EST
Slc17a1	0.241	0.062	0.114	0.927	1.397	2.214	6.236	6.435	X77241	96077_at	NPT1 gene; sodium-dependent phosphate cotransporter	sodium-phosphate transport system 1
Slc16a1	0.351	0.121	0.179	0.656	1.073	2.107	3.655	2.797	AF058055	101588_at		monocarboxylate transporter 1
EST	0.543	0.371	0.567	0.925	1.321	1.727	2.256	2.101	AW122860	93130_at	EST
Rasgrf1	0.042	0.214	0.369	1.223	1.394	3.066	7.195	7.219	L20899	96313_at	CDC25 gene; cell division; cell division cycle	CDC25 homolog
EST	0.032	0.114	0.495	0.774	2.116	2.509	3.617	3.282	AA755260	96134_at	EST
Abca4	0.087	0.264	0.583	0.802	1.831	2.162	3.018	2.847	AF000149	97730_at		ATP-binding cassette transporter
Calb1; CB; Calb-1; Brain-2	0.143	0.41	0.808	1.034	1.474	2.452	3.216	2.676	D26352	98133_at	Ca2+-binding protein; calbindin-D28k; spot35	spot35/calbindin-D28k
Guca1a	0.071	0.275	0.452	0.499	1.549	2.868	5.411	5.656	L36860	103038_at	calcium-binding protein; guanylate cyclase activating protein; membrane-associated protein	guanylate cyclase activating protein	calcium-binding protein
Sh3d2a	0.346	0.713	1.053	1.058	1.418	2.422	2.715	2.726	U58886	92673_at		endophilin I
Gnb5	0.256	0.574	0.718	1.063	2.264	3.02	3.598	3.191	L34290	100122_at	guanine nucleotide regulatory protein beta subunit	guanine nucleotide regulatory protein
Tac2	0.061	0.127	0.221	0.569	2.246	2.9	3.88	4.067	D14423	103548_at	neurokinin B; neuromedin K; preprotachykinin B; tachykinin	preprotachykinin B
Pla2g1br	0.13	0.227	0.53	0.664	1.8	2.451	3.034	2.96	D30779	98853_at	phospholipase A2 receptor	phospholipase A2 receptor
Opn1mw	0.053	0.175	0.225	0.314	1.705	4.486	5.712	4.574	AI462500	101679_at	EST
Tnfsf12	0.163	0.24	0.538	0.786	1.852	1.906	2.786	3.582	AF030100	93917_at		TWEAK
Dnm	0.388	0.537	0.995	1.127	1.859	1.835	2.721	3.11	L31397	103030_at	GTPase; dynamin; endocytosis	dynamin
Sncb	0.531	0.675	1.153	1.2	2.364	2.071	2.954	4.237	AI839708	100510_at	EST
Dnm	0.433	0.699	0.922	1.11	2.07	1.677	2.54	3.246	L31397	103031_g_at	GTPase; dynamin; endocytosis	dynamin
Eef1a2	0.452	0.852	0.869	1.189	2.471	2.113	3.106	3.421	L26479	94429_at	elongation factor-1 alpha	elongation factor-1 alpha
Scyd1	0.372	0.651	0.722	0.972	1.773	1.598	2.436	2.649	U92565	98008_at		fractalkine
D6Wsu176e	0.447	0.638	0.777	1.154	1.807	1.868	2.967	3.286	AA733372	97770_s_at	EST
1500005G05Rik	0.391	0.44	0.848	0.993	1.316	1.738	3.349	3.447	AI839690	103922_f_at	EST
D6Wsu176e	0.267	0.377	0.602	0.764	1.157	1.756	3.346	2.638	AW125506	95541_at	EST
Gas7	0.256	0.373	0.588	0.545	1.268	1.713	2.882	3.146	U19860	104678_at		growth arrest specific 7
Clu	0.235	0.339	0.531	0.706	1.337	1.82	3.428	4.016	D14077	95286_at	secretory protein; sulfated glycoprotein-2	sulfated glycoprotein-2
Hsp70-3	0.25	0.376	0.435	0.488	0.961	1.419	2.516	3.258	M12571	93875_at		68 kDa heat shock protein
EST	0.246	0.187	0.43	0.56	0.652	1.755	1.308	2.561	AA419684	95183_i_at	EST
Aqp1	0.115	0.081	0.137	0.14	0.857	30.904	98.692	66.535	L02914	93330_at		aquaporin-1	growth factor-induced delayed early response protein
Zap70	0.16	0.198	0.397	0.092	0.393	1.655	5.091	5.691	AI386093	93662_s_at	EST
EST	0.214	0.461	0.437	0.401	0.835	1.615	4.535	4.766	X05862	93833_s_at	DNA-binding protein; histone; histone H2A; histone H2B
Sgk	0.248	0.3	0.27	0.415	0.638	1.104	4.653	7.741	AW046181	97890_at	EST
Fgf1	0.418	0.074	0.44	0.641	1.284	1.765	3.033	1.473	M30641	100494_at	acidic fibroblast growth factor	fibroblast growth factor 1
Osmr	1.196	0.137	0.69	1.117	2.055	1.831	3.584	4.984	AB015978	102255_at	oncostatin M receptor beta; Osmr	oncostatin M receptor beta
Sema3f	0.608	0.754	0.208	1.503	2.033	1.312	2.742	2.222	AF080090	102623_at		semaphorin IV isoform b
Prp	0.297	0.168	0.054	0.297	1.265	2.283	5.433	6.496	M23236	93650_i_at	LIM repetitive element; proline-rich protein	proline-rich protein
Gstt1	0.432	0.51	0.087	0.567	2.435	2.159	2.363	3.387	X98055	95019_at	glutathione S-transferase theta; GSTT1 gene	glutathione S-transferase theta	phase II conjugation enzyme
Selenbp1	0.075	0.673	0.902	0.992	1.586	2.379	2.488	1.464	M32032	100596_at	Selenium-binding protein	selenium binding protein 1
EST	0.121	1.173	1.015	1.579	1.664	2.402	2.818	2.034	AI846673	103478_at	EST
C76628	0.146	2.053	1.511	1.46	3.593	2.742	4.187	4.035	C76628	101220_at	EST
EST	0.068	1.259	1.05	0.915	1.757	2.612	3.109	2.096	AI596540	96536_at	EST
Scn1a	0.088	0.877	0.76	0.954	1.808	2.145	2.55	2.93	L42339	94201_at	sodium channel 3	sodium channel 3
Il5; Il-5	0.195	1.257	1.28	1.526	2.496	3.257	2.599	3.54	X06271	98374_at	B-cell growth factor II; colony stimulating factor; eosinophil differentiation factor; interleukin 5; lymphokine	IL-5
Igh	0.152	1.305	1.05	1.159	1.465	2.505	3.465	3.16	AF042086	97577_f_at		immunoglobulin heavy chain V-DSP2.7-JH2 region
Prph2	0.044	0.837	1.878	1.968	2.822	2.938	4.017	4.554	X14770	101169_at	photoreceptor; rds gene	peripherin 2
EST	0.2	1.116	2.085	2.353	3.278	2.657	2.826	3.518	AI854450	103331_at	EST
Lhx3	0.115	0.639	1.665	2.261	2.413	2.703	2.6	3.574	L38248	102902_at		homeodomain protein
Slc7a8	0.024	0.329	0.979	1.65	2.074	2.312	1.985	2.163	AW122706	104214_at	EST
Rom1	0.073	0.459	1.286	1.641	2.208	2.374	2.599	2.604	M96760	93453_at	disk morphogenesis; disk rim; peripherin-related protein; rod photoreceptor; transmembrane protein	rod outer segment membrane protein 1
Sag	0.057	0.488	1.353	1.601	2.387	2.515	2.46	2.704	M24086	94150_at	S-antigen; Sag gene	S-antigen
Pde6b	0.01	0.287	1.162	1.458	2.105	2.417	2.708	2.83	X55968	94701_at	"3',5'-cyclic-nucleotide phosphodiesterase; membrane protein; transducin"	"phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide"
junB	0.059	0.81	2.276	2.575	2.173	3.394	3.329	6.06	U20735	102362_i_at		transcription factor junB
Slc12a4	0.109	1.059	1.914	1.447	1.716	2.7	2.551	3.452	AF047339	92450_at		erythroid K:Cl cotransporter
AW112037	0.089	0.335	0.842	0.817	1.724	2.065	2.313	1.496	AW122808	104282_at	EST
EST	0.079	0.24	1.036	1.203	1.545	2.193	3.207	2.055	AA690218	98569_at	EST
Rcvrn	0.015	0.11	0.626	1.104	2.724	2.659	2.979	2.578	X66196	101151_at	23 kDa protein; photoreceptor specific	23 kDa photoreceptor cell-specific protein
opsin	0.01	0.06	0.425	0.944	2.849	3.007	3.395	3.022	M36699	96567_at	opsin	opsin
Pde6g	0.039	0.21	0.986	1.296	2.068	2.389	2.537	2.659	Y00746	97732_at	"3',5'-cyclic-nucleotide phosphodiesterase; cyclic GMP phosphodiesterase gamma"	"phosphodiesterase 6G, cGMP-specific, rod, gamma"
Mod1	0.308	0.868	1.223	1.419	1.739	1.842	2.581	2.427	J02652	101082_at	malate NADP oxidoreductase; malic enzyme	malate oxidoreductase
Ache	0.104	0.654	0.93	1.545	2.33	1.881	2.52	3.188	X56518	104650_at	acetylcholinesterase	acetylcholinesterase
C030048H19Rik	0.095	0.642	0.914	1.323	2.657	2.354	3.625	4.925	AW122114	92526_f_at	EST
Npn1	0.277	1.18	1.305	1.54	2.294	1.974	3.184	4.31	Z31360	101168_at	P/L01 gene
Ptgds	0.021	0.335	0.515	0.723	1.092	1.568	2.698	5.878	AB006361	92546_r_at	prostaglandin D synthetase	prostaglandin D synthetase
Usp2	0.093	0.626	0.569	0.638	1.446	1.584	3.551	4.893	AF079565	92821_at		ubiquitin-specific protease UBP41
Ptgds	0.166	0.508	0.846	0.952	1.525	1.916	3.259	7.143	AB006361	92545_f_at	prostaglandin D synthetase	prostaglandin D synthetase
Rgr	0.205	0.671	0.768	1.098	1.442	2.04	2.847	4.814	AF076930	95331_at		RGR opsin
Ak4	0.182	0.863	1.892	1.357	1.447	1.765	4.587	4.925	AB020239	99521_at	mAK3b; adenylate kinase 3	adenylate kinase 3
Krt1-18; K18	0.283	0.922	1.172	1.028	1.184	1.951	3.558	2.765	M22832	94270_at	cytokeratin	cytokeratin
Mef2c	0.116	2.05	0.976	2.111	3.925	1.83	17.315	26.732	L13171	104590_at	DNA-binding protein; myocyte-specific enhancer factor 2; tissue specific expression; transcription factor	myocyte enhancer factor 2C
Cav	0.251	0.842	0.373	1.592	1.47	3.156	2.945	2.944	U07645	97849_at	"caveolin, caveolae, adipocytes, endothelial cells"	caveolin-1
Bhlhb2	0.084	0.64	0.075	1.108	2.196	2.684	6.892	9.586	Y07836	104701_at	basic-helix-loop-helix protein	basic-helix-loop-helix protein
Hk2; HKII; AI642394	0.151	1.257	0.151	1.186	1.42	2.017	8.732	17.697	Y11666	94375_at	hexokinase II	hexokinase II
Pcsk6	0.095	0.875	0.188	1.829	0.223	2.346	2.75	3.313	D50060	101196_at	PACE4A	PACE4A
Crybb2	0.08	0.063	0.476	1.769	1.402	3.879	4.991	2.256	M60559	100688_at	beta-B2 crystallin	beta-B2 crystallin	structural protein
Cacnb2	0.207	0.207	0.802	0.815	1.027	2.003	2.892	1.699	L20343	100757_at	L-type calcium channel beta subunit isoform
Gnb1	0.24	0.271	0.768	0.995	1.503	2.309	2.881	1.885	U29055	94853_at		G protein beta 36 subunit
Pla2g5	0.215	0.163	1	1.032	1.34	2.344	2.567	1.347	U66873	101328_at		phospholipase A2 group 5
Rs1h	0.042	0.031	0.585	0.913	0.507	3.756	5.791	3.544	AJ011381	101702_at	X-linked juvenile retinoschisis protein; Xlrs1 gene	X-linked juvenile retinoschisis protein
EST	0.306	0.087	1.326	1.63	1.922	2.442	2.169	2.051	Y12650	104014_at
4930406E12Rik	0.597	0.115	1.885	1.643	2.627	2.179	3.236	2.809	AW125311	98445_at	EST
Bcl6	0.225	0.084	1.158	1.055	1.975	2.403	5.358	5.882	U41465	103015_at		BCL-6
Gsg1	0.361	0.16	0.946	1.312	1.901	2.035	2.74	2.424	D87325	96620_at	GSG1	GSG1
Cacna2d3	0.574	0.119	1.071	1.577	1.701	2.485	3.793	3.604	AJ010949	98300_at	calcium channel alpha-2-delta-C subunit	calcium channel alpha-2-delta-C subunit
R74640	0.135	0.085	1.109	1.013	3.06	1.388	2.892	4.12	AW122995	93159_at	EST
Hzf-pending	0.499	0.401	1.067	1.143	1.875	1.592	2.573	3.235	AI848518	102691_at	EST
Pacsin1	0.396	0.394	0.93	0.893	1.633	1.722	2.612	3.499	X85124	92949_at	pacsin gene	PACSIN
Sdccagg28	0.529	0.492	1.189	1.036	1.791	1.601	2.922	3.271	AW049732	96735_at	EST
Rdh5	0.031	0.068	0.428	0.746	1.559	1.44	2.743	4.198	AF033195	101431_at		9-cis-retinol dehydrogenase
C030048H19Rik	0.088	0.144	0.889	1.391	2.051	2.028	3.21	5.517	AW122114	92525_i_at	EST
beta 1	0.076	0.102	0.659	0.931	2.122	1.977	2.486	3.445	L48687	102808_at	Na+ channel; beta-1 subunit; beta-subunit; sodium channel; voltage-dependent Na+ channel	voltage-dependent Na+ channel beta-1 subunit
Slc29a2	0.077	0.119	0.622	1.447	2.288	2.171	3.072	2.702	X86682	92950_at	HNP36 gene	HNP36 protein
Gabrr1	0.077	0.084	0.66	1.975	2.571	3.065	2.873	3.391	AF024620	100675_at		gamma-aminobutyric acid receptor rho1 subunit
EST	0.06	0.104	0.367	1.37	2.874	1.664	2.635	3.449	AI853899	95641_at	EST
Agt; Aogen; AI265500	0.144	0.152	2.019	2.862	5.506	4.986	3.569	5.539	AF045887	101887_at		angiotensinogen precursor
Slc25a17	0.138	0.159	1.351	1.916	3.002	2.111	2.639	3.754	AW124470	97473_at	EST
Hcn2	0.152	0.202	1.371	2.328	2.645	1.899	1.939	5.12	AJ225122	94194_s_at	cation channel; HAC1	"hyperpolarization-activated cation channel, HAC1"
Cpx2-pending	0.052	0.116	0.874	0.979	1.126	1.762	1.901	1.292	AF017639	102226_at		carboxypeptidase X2
Cncg	0.01	0.033	0.671	1.269	2.638	4.139	4.819	2.427	M84742	95389_at	cGMP-gated cation channel protein	cGMP-gated cation channel protein
Gzmm	0.046	0.095	1.003	1.527	2.007	2.293	2.741	2.686	AB015728	95363_at	granzyme M	granzyme M
D2Bwg0891e	0.068	0.113	1.403	1.617	1.811	2.144	2.451	2.104	AW121364	99641_at	EST
Ryr2	0.062	0.206	2.097	1.788	1.925	2.731	2.497	2.699	X78667	102653_at	ryanodine receptor; RYR2 gene	"ryanodine receptor 2, cardiac"
D6Wsu176e	0.093	0.304	1.757	1.956	3.007	2.739	2.503	3.693	AA733372	97771_r_at	EST
Ctgf	0.034	0.146	1.301	1.262	2.441	2.688	2.818	4.906	M70642	93294_at	cysteine-rich protein; growth factor-inducible gene	FISP-12 protein
Grid1	0.183	0.215	1.12	1.427	1.356	2.482	1.931	2.77	D10171	94619_at	delta 1 subunit; glutamate receptor channel	glutamate receptor channel subunit delta-1
Vcam1	0.066	0.109	1.334	4.048	6.175	5.42	2.339	2.653	M84487	92558_at	vascular cell adhesion molecule-1	vascular cell adhesion molecule-1
Kcnb1	0.088	0.178	0.642	1.258	1.362	2.103	5.15	0.397	M64228	101308_at	ion channel; potassium channel protein	potassium channel protein
Gabra1	0.114	0.049	0.541	1.128	1.13	2.205	3.141	0.316	X61430	92938_at	GABA-A receptor alpha-1 subunit; ligand-gated channel; membrane protein	GABA A receptor alpha 1 subunit
F3	0.079	0.135	1.355	1.462	2.157	0.241	5.745	7.004	M26071	97689_at	membrane-bound glycoprotein; tissue factor	coagulation factor III
Mup4	0.237	0.153	0.842	0.388	1.767	0.199	2.251	9.182	M16358	101682_f_at	major urinary protein	major urinary protein IV
Prrx2	0.214	0.176	3.331	0.146	2.255	4.78	2.02	8.294	X52875	103327_at	homeobox gene; homeodomain region; Prx2 homeobox gene	"surface antigen, homeo box of paired rule"
AI266885	0.227	1.106	0.124	0.166	0.307	0.222	4.114	2.46	AI266885	104213_at	EST