Source: Interfolio F180


Meng Yuan, PhD

Institute Investigator
Department of Integrative Structural and Computational Biology


 Email

Education

2012 – 2016, Ph.D. in Structural and Molecular Biology, University of Edinburgh 
2009 – 2012, Master in Nutrition and Food Safety, Tianjin University of Science and Technology  
2005 – 2009, Jiangnan University Bachelor in Food Safety

Professional Experience

2022 – 2023 Sr. Staff Scientist, The Scripps Research Institute  
2021 – 2022 Staff Scientist, The Scripps Research Institute 
2016 – 2021 Postdoctoral Research Associate, The Scripps Research Institute

Awards & Professional Activities

2021 “Research of the Year 2020”, C&EN
2021 “Best paper of Cell Reports 2020”, Cell Reports
2020 “Molecule of the Month” for June 2020, Protein Data Bank
2012 Darwin Trust Postgraduate Scholarships, UK
2012 “Outstanding Paper 2012”, Chinese Institute of Food Science and Technology

Selected Publications

Yuan, Meng; Feng, Ziqi; Lv, Huibin; So, Natalie; Shen, Ivana R.; Tan, Timothy J C; Teo, Qi W.; Ouyang, Wenha O.; Talmage, Logan; Wilson, I A.; Wu, Ni C. Widespread impact of immunoglobulin V-gene allelic polymorphisms on antibody reactivity. Cell reports 2023, 42, 113194.

Yuan, Meng; Huang, Deli; Lee, Chang-Chun D.; Wu, Ni C.; Jackson, Abigail M.; Zhu, Xueyong; Liu, Hejun; Peng, Linghang; van Gils, Marit J.; Sanders, Rogier W.; Burton, Dennis R.; Reincke, S M.; Prüss, Harald; Kreye, Jakob; Nemazee, David; Ward, Andrew B.; Wilson, I A. Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants. Science 2021, 373, 818-823.

Yuan, Meng; Liu, Hejun; Wu, Ni C.; Lee, Chang-Chun D.; Zhu, Xueyong; Zhao, Fangzhu; Huang, Deli; Yu, Wenli; Hua, Yuanzi; Tien, Henry; Rogers, Thomas F.; Landais, Elise; Sok, Devin; Jardine, Joseph G.; Burton, Dennis R.; Wilson, I A. Structural basis of a shared antibody response to SARS-CoV-2. Science 2020, 369, 1119-1123.

Yuan, Meng; Wu, Ni C.; Zhu, Xueyong; Lee, Chang-Chun D.; So, Ray T Y; Lv, Huibin; Mok, Chris K P; Wilson, I A. A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV. Science 2020, 368, 630-633.

Yuan, Meng; Cottrell, Christopher A.; Ozorowski, Gabriel; van Gils, Marit J.; Kumar, Sonu; Wu, Ni C.; Sarkar, Anita; Torres, Jonathan L.; de Val, Natalia; Copps, Jeffrey; Moore, John P.; Sanders, Rogier W.; Ward, Andrew B.; Wilson, I A. Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host & Microbe 2019, 25, 873-883.e5.

Yuan, Meng; McNae, Iain W.; Chen, Yiyuan; Blackburn, Eliz A.; Wear, M A.; Michels, Paul A M; Fothergill-Gilmore, Lind A.; Hupp, Ted; Walkinshaw, Malcolm D. An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor. The Biochemical Journal 2018, 475, 1821-1837.