Source: Interfolio F180
Megan Ken, MD, PhD
Scripps Research Joint Appointments
Education
M.D., Duke University School of Medicine, 2023Ph.D. (Biochemistry), Duke University School of Medicine, 2022
B.A. (Biology & Chemistry) Washington University in St. Louis, 2013
Awards & Professional Activities
2024 NIH Director's Early Independence Award
2024 Ellen Browning Scripps Foundation Award
2022 Chancellor’s Award for Research Excellence, Duke University
2019 Ruth L. Kirschstein Individual Predoctoral NRSA for MD/PhD Fellowship (F30), NIH/NIAID
2019 Michelle Winn Inclusive Excellence Award, Duke University School of Medicine
Selected Publications
Ken, Megan L.; Roy, Rohit; Geng, Ainan; Ganser, Lau R.; Manghrani, Akanksha; Cullen, B R.; Schulze-Gahmen, Ursula; Herschlag, Daniel; Al-Hashimi, Hashi M. RNA conformational propensities determine cellular activity. 2023, 617, 835-841.
Kelly, Megan L.; Chu, Chia-Chieh C.; Shi, Honglue; Ganser, Lau R.; Bogerd, Hal P.; Huynh, Kelly; Hou, Yuze; Cullen, B R.; Al-Hashimi, Hashi M. Understanding the characteristics of nonspecific binding of drug-like compounds to canonical stem-loop RNAs and their implications for functional cellular assays. 2021, 27, 12-26.
Ganser, Lau R.; Kelly, Megan L.; Patwardhan, Neeraj N N.; Hargrove, Amanda E.; Al-Hashimi, Hashi M. Demonstration that Small Molecules can Bind and Stabilize Low-abundance Short-lived RNA Excited Conformational States. 2020, 432, 1297-1304.
Ganser, Lau R.; Kelly, Megan L.; Herschlag, Daniel; Al-Hashimi, Hashi M. The roles of structural dynamics in the cellular functions of RNAs. 2019, 20, 474-489.
Ganser, Lau R.; Lee, Janghyun; Rangadurai, Atul; Merriman, Dawn K.; Kelly, Megan L.; Kansal, Aman D.; Sathyamoorthy, Bharathwaj; Al-Hashimi, Hashi M. High-performance virtual screening by targeting a high-resolution RNA dynamic ensemble. 2018, 25, 425-434.
Kelly, Megan; Su, Chih- Y.; Schaber, Chad; Crowley, Jan R.; Hsu, Fong-Fu F.; Carlson, John R.; Odom, Aud R. Malaria parasites produce volatile mosquito attractants. 2015, 6.