The Friedlander Laboratory
Department of Cell Biology
The Scripps Research Institute, La Jolla, CA
Microarray Home Statistical Analyses Gene Search
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The Friedlander Laboratory Department of Cell Biology |
The Scripps Research Institute, La Jolla, CA Microarray Home Statistical Analyses Gene Search |
The gene expression profiles of thousands of genes in the developing post-natal mouse retina were analyzed by hybridization to Affymetrix Mu74 Av2 in triplicate and compared. The 2635 known gene sequences and 2794 ESTs sequences that are expressed at least 3-fold above background levels in at least one of the eight timepoints tested were clustered based on expression profiles and intensities. Overall, known genes with decreasing expression (clusters 4, 7, and 8) have higher probabilities for functions involving proliferation and neuronal differentiation, while genes with increasing expression profiles (cluster 2, 3, and 6) have higher probabilities of vision related functions. Profile clusters with varying changes in expression throughout (clusters 9 and 10) were found to contain a majority of known vascularization-related properties.
"P#" = post-natal day (mouse age in number of days after birth)
Recently a problem was brought to our attention where the cluster 4 link actually was downloading the list from cluster 5. This problem has now been resolved. We apologize for any inconvenience. (2-23-05)
Click on the graph to get a larger version, choose the table link to see the data underlying the graph.
